Fatal Myelotoxicity Following Palliative Chemotherapy With Cisplatin and Gemcitabine in a Patient With Stage IV Cholangiocarcinoma Linked to Post Mortem Diagnosis of Fanconi Anemia

by Nils W. Engel, Simon Schliffke, Ulrich Schüller, Ulrich Schüller, Ulrich Schüller, Christian Frenzel, Carsten Bokemeyer, Christian Kubisch, Davor Lessel
Published 2019-05-01

DIMEimmune: Robust estimation of infiltrating lymphocytes in CNS tumors from DNA methylation profiles

by Sepehr Safaei, Malte Mohme, Judith Niesen, Ulrich Schüller, Michael Bockmayr
Published 2021-01-01

hGFAP-mediated GLI2 overexpression leads to early death and severe cerebellar malformations with rare tumor formation

by Judith Niesen, Irm Hermans-Borgmeyer, Christina Krüger, Melanie Schoof, Franziska Modemann, Ulrich Schüller
Published 2023-09-01

Subgroup-specific immune and stromal microenvironment in medulloblastoma

by Michael Bockmayr, Malte Mohme, Frederick Klauschen, Beate Winkler, Jan Budczies, Stefan Rutkowski, Ulrich Schüller
Published 2018-09-01

MYC overexpression and SMARCA4 loss cooperate to drive medulloblastoma formation in mice

by Carolin Göbel, Shweta Godbole, Melanie Schoof, Dörthe Holdhof, Catena Kresbach, Carolin Loose, Julia Neumann, Ulrich Schüller
Published 2023-11-01

Canonical Wnt Signaling Drives Tumor-Like Lesions from Sox2-Positive Precursors of the Murine Olfactory Epithelium.

by Nils W Engel, Julia E Neumann, Julia Ahlfeld, Annika K Wefers, Daniel J Merk, Jasmin Ohli, Ulrich Schüller
Published 2016-01-01

Neurogenesis from Sox2 expressing cells in the adult cerebellar cortex

by Julia Ahlfeld, Severin Filser, Felix Schmidt, Annika K. Wefers, Daniel J. Merk, Rainer Glaß, Jochen Herms, Ulrich Schüller
Published 2017-07-01

Unclassifiable CNS tumors in DNA methylation-based classification: clinical challenges and prognostic impact

by Richard Drexler, Florian Brembach, Jennifer Sauvigny, Franz L. Ricklefs, Alicia Eckhardt, Helena Bode, Jens Gempt, Katrin Lamszus, Manfred Westphal, Ulrich Schüller, Malte Mohme
Published 2024-01-01

Gliosarcoma Is Driven by Alterations in PI3K/Akt, RAS/MAPK Pathways and Characterized by Collagen Gene Expression Signature

by Bartosz Wojtas, Bartlomiej Gielniewski, Kamil Wojnicki, Marta Maleszewska, Shamba S. Mondal, Pawel Nauman, Wieslawa Grajkowska, Rainer Glass, Ulrich Schüller, Christel Herold-Mende, Bozena Kaminska
Published 2019-02-01

The tumor suppressor CREBBP and the oncogene MYCN cooperate to induce malignant brain tumors in mice

by Melanie Schoof, Gefion Dorothea Epplen, Carolin Walter, Annika Ballast, Dörthe Holdhof, Carolin Göbel, Sina Neyazi, Julian Varghese, Thomas Karl Albert, Kornelius Kerl, Ulrich Schüller
Published 2023-07-01

Molecular profiling of an osseous metastasis in glioblastoma during checkpoint inhibition: potential mechanisms of immune escape

by Malte Mohme, Cecile L. Maire, Simon Schliffke, Simon A. Joosse, Malik Alawi, Jakob Matschke, Ulrich Schüller, Judith Dierlamm, Tobias Martens, Klaus Pantel, Sabine Riethdorf, Katrin Lamszus, Manfred Westphal
Published 2020-03-01

Co-activation of Sonic hedgehog and Wnt signaling in murine retinal precursor cells drives ocular lesions with features of intraocular medulloepithelioma

by Matthias Dottermusch, Piotr Sumisławski, Julia Krevet, Maximilian Middelkamp, Hannah Voß, Bente Siebels, Harald Bartsch, Karl Sotlar, Peter Meyer, Stephan Frank, Andrey Korshunov, Markus Glatzel, Ulrich Schüller, Julia E. Neumann
Published 2021-11-01

G2 checkpoint targeting via Wee1 inhibition radiosensitizes EGFRvIII-positive glioblastoma cells

by Meryem H. Cetin, Thorsten Rieckmann, Konstantin Hoffer, Britta Riepen, Sabrina Christiansen, Fruzsina Gatzemeier, Simon Feyerabend, Melanie Schoof, Ulrich Schüller, Cordula Petersen, Martin Mynarek, Kai Rothkamm, Malte Kriegs, Nina Struve
Published 2023-01-01

Preclinical patient‐derived modeling of castration‐resistant prostate cancer facilitates individualized assessment of homologous recombination repair deficient disease

by Mohamed E. Elsesy, Su Jung Oh‐Hohenhorst, Christoph Oing, Alicia Eckhardt, Susanne Burdak‐Rothkamm, Malik Alawi, Christian Müller, Ulrich Schüller, Tobias Maurer, Gunhild vonAmsberg, Cordula Petersen, Kai Rothkamm, Wael Y. Mansour
Published 2023-06-01

Translation of atherosclerotic plaque phase-contrast CT imaging from synchrotron radiation to a conventional lab-based X-ray source.

by Tobias Saam, Julia Herzen, Holger Hetterich, Sandra Fill, Marian Willner, Marco Stockmar, Klaus Achterhold, Irene Zanette, Timm Weitkamp, Ulrich Schüller, Sigrid Auweter, Silvia Adam-Neumair, Konstantin Nikolaou, Maximilian F Reiser, Franz Pfeiffer, Fabian Bamberg
Published 2013-01-01

The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration

by Melanie Schoof, Michael Launspach, Dörthe Holdhof, Lynhda Nguyen, Verena Engel, Severin Filser, Finn Peters, Jana Immenschuh, Malte Hellwig, Judith Niesen, Volker Mall, Birgit Ertl-Wagner, Christian Hagel, Michael Spohn, Beat Lutz, Jan Sedlacik, Daniela Indenbirken, Daniel J. Merk, Ulrich Schüller
Published 2019-12-01

Mitochondrial DNA mutations in Medulloblastoma

by Viktoria L. E. Funke, Sarah Sandmann, Viktoria Melcher, Jochen Seggewiss, Judit Horvath, Natalie Jäger, Marcel Kool, David T. W. Jones, Stefan M. Pfister, Till Milde, Stefan Rutkowski, Martin Mynarek, Julian Varghese, Ronald Sträter, Stephan Rust, Anja Seelhöfer, Janine Reunert, Barbara Fiedler, Ulrich Schüller, Thorsten Marquardt, Kornelius Kerl
Published 2023-07-01

Group-specific cellular metabolism in Medulloblastoma

by Viktoria L. E. Funke, Carolin Walter, Viktoria Melcher, Lanying Wei, Sarah Sandmann, Marc Hotfilder, Julian Varghese, Natalie Jäger, Marcel Kool, David T. W. Jones, Stefan M. Pfister, Till Milde, Martin Mynarek, Stefan Rutkowski, Jochen Seggewiss, Daniela Jeising, Flavia W. de Faria, Thorsten Marquardt, Thomas K. Albert, Ulrich Schüller, Kornelius Kerl
Published 2023-06-01

Twinning to reduce research and innovation inequalities in paediatric solid tumours across Europe

by Jelena Rascon, Renata Blackute, Alma Cerkauskiene, Sabine Taschner-Mandl, Nuno Andrade, Adriana Planinic, Stefan Rutkowski, Ulrich Schuller, Karsten Nysom, Ruta Tuckuviene, Jesper Brok, Kjeld Schmiegelow, Marry M. van den Heuvel-Eibrink, M.E. Madeleine van der Perk, Riccardo Haupt, Monica Muraca, Davide Saraceno, Birgit Geoerger, Giorgia Manuzi, Ruth Ladenstein
Published 2024-06-01

Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors

by Monika Graf, Marta Interlandi, Natalia Moreno, Dörthe Holdhof, Carolin Göbel, Viktoria Melcher, Julius Mertins, Thomas K. Albert, Dennis Kastrati, Amelie Alfert, Till Holsten, Flavia de Faria, Michael Meisterernst, Claudia Rossig, Monika Warmuth-Metz, Johannes Nowak, Gerd Meyer zu Hörste, Chloe Mayère, Serge Nef, Pascal Johann, Michael C. Frühwald, Martin Dugas, Ulrich Schüller, Kornelius Kerl
Published 2022-03-01