Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis.

by James Yarmolinsky, Virginia Díez-Obrero, Tom G Richardson, Marie Pigeyre, Jennifer Sjaarda, Guillaume Paré, Venexia M Walker, Emma E Vincent, Vanessa Y Tan, Mireia Obón-Santacana, Demetrius Albanes, Jochen Hampe, Andrea Gsur, Heather Hampel, Rish K Pai, Mark Jenkins, Steven Gallinger, Graham Casey, Wei Zheng, Christopher I Amos, International Lung Cancer Consortium, PRACTICAL consortium, MEGASTROKE consortium, George Davey Smith, Richard M Martin, Victor Moreno
Published 2022-02-01

Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases

by Adrien Georges, Min-Lee Yang, Takiy-Eddine Berrandou, Mark K. Bakker, Ozan Dikilitas, Soto Romuald Kiando, Lijiang Ma, Benjamin A. Satterfield, Sebanti Sengupta, Mengyao Yu, Jean-François Deleuze, Delia Dupré, Kristina L. Hunker, Sergiy Kyryachenko, Lu Liu, Ines Sayoud-Sadeg, Laurence Amar, Chad M. Brummett, Dawn M. Coleman, Valentina d’Escamard, Peter de Leeuw, Natalia Fendrikova-Mahlay, Daniella Kadian-Dodov, Jun Z. Li, Aurélien Lorthioir, Marco Pappaccogli, Aleksander Prejbisz, Witold Smigielski, James C. Stanley, Matthew Zawistowski, Xiang Zhou, Sebastian Zöllner, FEIRI investigators, International Stroke Genetics Consortium (ISGC) Intracranial Aneurysm Working Group, MEGASTROKE, Philippe Amouyel, Marc L. De Buyzere, Stéphanie Debette, Piotr Dobrowolski, Wojciech Drygas, Heather L. Gornik, Jeffrey W. Olin, Jerzy Piwonski, Ernst R. Rietzschel, Ynte M. Ruigrok, Miikka Vikkula, Ewa Warchol Celinska, Andrzej Januszewicz, Iftikhar J. Kullo, Michel Azizi, Xavier Jeunemaitre, Alexandre Persu, Jason C. Kovacic, Santhi K. Ganesh, Nabila Bouatia-Naji
Published 2021-10-01

Author Correction: Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases

by Adrien Georges, Min-Lee Yang, Takiy-Eddine Berrandou, Mark K. Bakker, Ozan Dikilitas, Soto Romuald Kiando, Lijiang Ma, Benjamin A. Satterfield, Sebanti Sengupta, Mengyao Yu, Jean-François Deleuze, Delia Dupré, Kristina L. Hunker, Sergiy Kyryachenko, Lu Liu, Ines Sayoud-Sadeg, Laurence Amar, Chad M. Brummett, Dawn M. Coleman, Valentina d’Escamard, Peter de Leeuw, Natalia Fendrikova-Mahlay, Daniella Kadian-Dodov, Jun Z. Li, Aurélien Lorthioir, Marco Pappaccogli, Aleksander Prejbisz, Witold Smigielski, James C. Stanley, Matthew Zawistowski, Xiang Zhou, Sebastian Zöllner, FEIRI investigators, International Stroke Genetics Consortium (ISGC) Intracranial Aneurysm Working Group, MEGASTROKE, Philippe Amouyel, Marc L. De Buyzere, Stéphanie Debette, Piotr Dobrowolski, Wojciech Drygas, Heather L. Gornik, Jeffrey W. Olin, Jerzy Piwonski, Ernst R. Rietzschel, Ynte M. Ruigrok, Miikka Vikkula, Ewa Warchol Celinska, Andrzej Januszewicz, Iftikhar J. Kullo, Michel Azizi, ARCADIA Investigators, Xavier Jeunemaitre, Alexandre Persu, Jason C. Kovacic, Santhi K. Ganesh, Nabila Bouatia-Naji
Published 2022-04-01

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

by Nora Franceschini, Claudia Giambartolomei, Paul S. de Vries, Chris Finan, Joshua C. Bis, Rachael P. Huntley, Ruth C. Lovering, Salman M. Tajuddin, Thomas W. Winkler, Misa Graff, Maryam Kavousi, Caroline Dale, Albert V. Smith, Edith Hofer, Elisabeth M. van Leeuwen, Ilja M. Nolte, Lingyi Lu, Markus Scholz, Muralidharan Sargurupremraj, Niina Pitkänen, Oscar Franzén, Peter K. Joshi, Raymond Noordam, Riccardo E. Marioni, Shih-Jen Hwang, Solomon K. Musani, Ulf Schminke, Walter Palmas, Aaron Isaacs, Adolfo Correa, Alan B. Zonderman, Albert Hofman, Alexander Teumer, Amanda J. Cox, André G. Uitterlinden, Andrew Wong, Andries J. Smit, Anne B. Newman, Annie Britton, Arno Ruusalepp, Bengt Sennblad, Bo Hedblad, Bogdan Pasaniuc, Brenda W. Penninx, Carl D. Langefeld, Christina L. Wassel, Christophe Tzourio, Cristiano Fava, Damiano Baldassarre, Daniel H. O’Leary, Daniel Teupser, Diana Kuh, Elena Tremoli, Elmo Mannarino, Enzo Grossi, Eric Boerwinkle, Eric E. Schadt, Erik Ingelsson, Fabrizio Veglia, Fernando Rivadeneira, Frank Beutner, Ganesh Chauhan, Gerardo Heiss, Harold Snieder, Harry Campbell, Henry Völzke, Hugh S. Markus, Ian J. Deary, J. Wouter Jukema, Jacqueline de Graaf, Jacqueline Price, Janne Pott, Jemma C. Hopewell, Jingjing Liang, Joachim Thiery, Jorgen Engmann, Karl Gertow, Kenneth Rice, Kent D. Taylor, Klodian Dhana, Lambertus A. L. M. Kiemeney, Lars Lind, Laura M. Raffield, Lenore J. Launer, Lesca M. Holdt, Marcus Dörr, Martin Dichgans, Matthew Traylor, Matthias Sitzer, Meena Kumari, Mika Kivimaki, Mike A. Nalls, Olle Melander, Olli Raitakari, Oscar H. Franco, Oscar L. Rueda-Ochoa, Panos Roussos, Peter H. Whincup, Philippe Amouyel, Philippe Giral, Pramod Anugu, Quenna Wong, Rainer Malik, Rainer Rauramaa, Ralph Burkhardt, Rebecca Hardy, Reinhold Schmidt, Renée de Mutsert, Richard W. Morris, Rona J. Strawbridge, S. Goya Wannamethee, Sara Hägg, Sonia Shah, Stela McLachlan, Stella Trompet, Sudha Seshadri, Sudhir Kurl, Susan R. Heckbert, Susan Ring, Tamara B. Harris, Terho Lehtimäki, Tessel E. Galesloot, Tina Shah, Ulf de Faire, Vincent Plagnol, Wayne D. Rosamond, Wendy Post, Xiaofeng Zhu, Xiaoling Zhang, Xiuqing Guo, Yasaman Saba, MEGASTROKE Consortium, Abbas Dehghan, Adrie Seldenrijk, Alanna C. Morrison, Anders Hamsten, Bruce M. Psaty, Cornelia M. van Duijn, Deborah A. Lawlor, Dennis O. Mook-Kanamori, Donald W. Bowden, Helena Schmidt, James F. Wilson, James G. Wilson, Jerome I. Rotter, Joanna M. Wardlaw, John Deanfield, Julian Halcox, Leo-Pekka Lyytikäinen, Markus Loeffler, Michele K. Evans, Stéphanie Debette, Steve E. Humphries, Uwe Völker, Vilmundur Gudnason, Aroon D. Hingorani, Johan L. M. Björkegren, Juan P. Casas, Christopher J. O’Donnell
Published 2018-12-01

Genome-wide meta-analysis identifies 3 novel loci associated with stroke.

by Malik, Rainer, Rannikmäe, Kristiina, Traylor, Matthew, Georgakis, Marios K, Sargurupremraj, Muralidharan, Markus, Hugh S, Hopewell, Jemma C, Debette, Stephanie, Sudlow, Cathie LM, Dichgans, Martin, MEGASTROKE consortium and the International Stroke Genetics Consortium
Published 2018

Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study.

by Larsson, Susanna C, Traylor, Matthew, Burgess, Stephen, Boncoraglio, Giorgio B, Jern, Christina, Michaëlsson, Karl, Markus, Hugh S, MEGASTROKE project of the International Stroke Genetics Consortium
Published 2019

Genome‐wide meta‐analysis identifies 3 novel loci associated with stroke

by Malik, R, Rannikmäe, K, Traylor, M, Georgakis, M, Sargurupremraj, M, Markus, H, Hopewell, J, Debette, S, Sudlow, C, Dichgans, M
Published 2019

The role of haematological traits in risk of ischaemic stroke and its subtypes

by Harshfield, Eric L, Sims, Matthew C, Traylor, Matthew, Ouwehand, Willem H, Markus, Hugh S
Published 2019

Genetic associations of adult height with risk of cardioembolic and other subtypes of ischemic stroke: a mendelian randomization study in multiple ancestries

by Linden, AB, Clarke, R, Hammami, I, Hopewell, JC, Guo, Y, Whiteley, WN, Lin, K, Turnbull, I, Chen, Y, Yu, C, Lv, J, Offer, A, Bennett, D, Walters, RG, Li, L, Chen, Z, Parish, S
Published 2022

Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: cohort study of 306 473 UK Biobank participants.

by Rutten-Jacobs, Loes Ca, Larsson, Susanna C, Malik, Rainer, Rannikmäe, Kristiina, MEGASTROKE consortium, International Stroke Genetics Consortium, Sudlow, Cathie L, Dichgans, Martin, Markus, Hugh S, Traylor, Matthew
Published 2018

Serum 25-Hydroxyvitamin D Concentrations and Ischemic Stroke and Its Subtypes.

by Larsson, Susanna C, Traylor, Matthew, Mishra, Aniket, Howson, Joanna MM, Michaëlsson, Karl, Markus, Hugh S, MEGASTROKE Project of the International Stroke Genetics Consortium
Published 2018

Serum 25-Hydroxyvitamin D Concentrations and Ischemic Stroke and Its Subtypes A Mendelian Randomization Study

by Larsson, Susanna C, Traylor, Matthew, Mishra, Aniket, Howson, Joanna MM, Michaelsson, Karl, Markus, Hugh S
Published 2018

A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology

by Vries, P.S. de, Sabater-Lleal, M., Huffman, J.E., Marten, J., Song, C., Pankratz, N., Bartz, T.M., Haan, H.G. de, Delgado, G.E., Eicher, J.D., Martinez-Perez, A., Ward-Caviness, C.K., Brody, J.A., Chen, M.H., Maat, M.P.M. de, Franberg, M., Gill, D., Kleber, M.E., Rivadeneira, F., Soria, J.M., Tang, W.H., Tofler, G.H., Uitterlinden, A.G., Vlieg, A.V., Seshadri, S., Boerwinkle, E., Davies, N.M., Giese, A.K., Ikram, M.K., Kittner, S.J., McKnight, B., Psaty, B.M., Reiner, A.P., Sargurupremraj, M., Taylor, K.D., Fornage, M., Hamsten, A., Marz, W., Rosendaal, F.R., Souto, J.C., Dehghan, A., Johnson, A.D., Morrison, A.C., O'Donnell, C.J., Smith, N.L., INVENT Consortium, MEGASTROKE Consortium Intl
Published 2019

Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study

by Larsson, S, Traylor, M, Burgess, S, Boncoraglio, G, Jern, C, Michaëlsson, K, Markus, H, Megastroke Project Of The International Stroke Genetics Consortium
Published 2019

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.

by Franceschini, Nora, Giambartolomei, Claudia, de Vries, Paul S, Finan, Chris, Bis, Joshua C, Huntley, Rachael P, Lovering, Ruth C, Tajuddin, Salman M, Winkler, Thomas W, Graff, Misa, Kavousi, Maryam, Dale, Caroline, Smith, Albert V, Hofer, Edith, van Leeuwen, Elisabeth M, Nolte, Ilja M, Lu, Lingyi, Scholz, Markus, Sargurupremraj, Muralidharan, Pitkänen, Niina, Franzén, Oscar, Joshi, Peter K, Noordam, Raymond, Marioni, Riccardo E, Hwang, Shih-Jen, Musani, Solomon K, Schminke, Ulf, Palmas, Walter, Isaacs, Aaron, Correa, Adolfo, Zonderman, Alan B, Hofman, Albert, Teumer, Alexander, Cox, Amanda J, Uitterlinden, André G, Wong, Andrew, Smit, Andries J, Newman, Anne B, Britton, Annie, Ruusalepp, Arno, Sennblad, Bengt, Hedblad, Bo, Pasaniuc, Bogdan, Penninx, Brenda W, Langefeld, Carl D, Wassel, Christina L, Tzourio, Christophe, Fava, Cristiano, Baldassarre, Damiano, O'Leary, Daniel H, Teupser, Daniel, Kuh, Diana, Tremoli, Elena, Mannarino, Elmo, Grossi, Enzo, Boerwinkle, Eric, Schadt, Eric E, Ingelsson, Erik, Veglia, Fabrizio, Rivadeneira, Fernando, Beutner, Frank, Chauhan, Ganesh, Heiss, Gerardo, Snieder, Harold, Campbell, Harry, Völzke, Henry, Markus, Hugh S, Deary, Ian J, Jukema, J Wouter, de Graaf, Jacqueline, Price, Jacqueline, Pott, Janne, Hopewell, Jemma C, Liang, Jingjing, Thiery, Joachim, Engmann, Jorgen, Gertow, Karl, Rice, Kenneth, Taylor, Kent D, Dhana, Klodian, Kiemeney, Lambertus ALM, Lind, Lars, Raffield, Laura M, Launer, Lenore J, Holdt, Lesca M, Dörr, Marcus, Dichgans, Martin, Traylor, Matthew, Sitzer, Matthias, Kumari, Meena, Kivimaki, Mika, Nalls, Mike A, Melander, Olle, Raitakari, Olli, Franco, Oscar H, Rueda-Ochoa, Oscar L, Roussos, Panos, Whincup, Peter H, Amouyel, Philippe, Giral, Philippe, Anugu, Pramod, Wong, Quenna, Malik, Rainer, Rauramaa, Rainer, Burkhardt, Ralph, Hardy, Rebecca, Schmidt, Reinhold, de Mutsert, Renée, Morris, Richard W, Strawbridge, Rona J, Wannamethee, S Goya, Hägg, Sara, Shah, Sonia, McLachlan, Stela, Trompet, Stella, Seshadri, Sudha, Kurl, Sudhir, Heckbert, Susan R, Ring, Susan, Harris, Tamara B, Lehtimäki, Terho, Galesloot, Tessel E, Shah, Tina, de Faire, Ulf, Plagnol, Vincent, Rosamond, Wayne D, Post, Wendy, Zhu, Xiaofeng, Zhang, Xiaoling, Guo, Xiuqing, Saba, Yasaman, MEGASTROKE Consortium, Dehghan, Abbas, Seldenrijk, Adrie, Morrison, Alanna C, Hamsten, Anders, Psaty, Bruce M, van Duijn, Cornelia M, Lawlor, Deborah A, Mook-Kanamori, Dennis O, Bowden, Donald W, Schmidt, Helena, Wilson, James F, Wilson, James G, Rotter, Jerome I, Wardlaw, Joanna M, Deanfield, John, Halcox, Julian, Lyytikäinen, Leo-Pekka, Loeffler, Markus, Evans, Michele K, Debette, Stéphanie, Humphries, Steve E, Völker, Uwe, Gudnason, Vilmundur, Hingorani, Aroon D, Björkegren, Johan LM, Casas, Juan P, O'Donnell, Christopher J
Published 2018

Plasma Phospholipid Fatty Acids, FADS1 and Risk of 15 Cardiovascular Diseases: A Mendelian Randomisation Study

by Yuan, Shuai, Bäck, Magnus, Bruzelius, Maria, Mason, Amy M., Burgess, Stephen, Larsson, Susanna
Published 2019

Circulating Vitamin K₁ Levels in Relation to Ischemic Stroke and Its Subtypes: A Mendelian Randomization Study.

by Larsson, Susanna C, Traylor, Matthew, Markus, Hugh S
Published 2018

Genetically Proxied Inhibition of Coagulation Factors and Risk of Cardiovascular Disease: A Mendelian Randomization Study.

by Yuan, Shuai, Burgess, Stephen, Laffan, Mike, Mason, Amy M, Dichgans, Martin, Gill, Dipender, Larsson, Susanna C
Published 2021

Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels

by Sabater-Lleal, M., Huffman, J.E., Vries, P.S. de, Marten, J., Mastrangelo, M.A., Song, C., Pankratz, N., Ward-Caviness, C.K., Yanek, L.R., Trompet, S., Delgado, G.E., Guo, X., Bartz, T.M., Martinez-Perez, A., Germain, M., Haan, H.G. de, Ozel, A.B., Polasek, O., Smith, A.V., Eicher, J.D., Reiner, A.P., Tang, W., Davies, N.M., Stott, D.J., Rotter, J.I., Tofler, G.H., Boerwinkle, E., Maat, M.P.M. de, Kleber, M.E., Welsh, P., Brody, J.A., Chen, M.H., Vaidya, D., Soria, J.M., Suchon, P., Hylckama Vlieg, A. van, Desch, K.C., Kolcic, I., Joshi, P.K., Launer, L.J., Harris, T.B., Campbell, H., Rudan, I., Becker, D.M., Li, J.Z., Rivadeneira, F., Uitterlinden, A.G., Hofman, A., Franco, O.H., Cushman, M., Psaty, B.M., Morange, P.E., McKnight, B., Chong, M.R., Fernandez-Cadenas, I., Rosand, J., Lindgren, A., Gudnason, V., Wilson, J.F., Hayward, C., Ginsburg, D., Fornage, M., Rosendaal, F.R., Souto, J.C., Becker, L.C., Jenny, N.S., Marz, W., Jukema, J.W., Dehghan, A., Tregouet, D.A., Morrison, A.C., Johnson, A.D., O'Donnell, C.J., Strachan, D.P., Lowenstein, C.J., Smith, N.L., INVENT Consortium MEGASTROKE Cons
Published 2019

Homocysteine and small vessel stroke: A mendelian randomization analysis.

by Larsson, Susanna C, Traylor, Matthew, Markus, Hugh S
Published 2019