Translating Human Cancer Sequences Into Personalized Porcine Cancer Models

by Chunlong Xu, Sen Wu, Lawrence B. Schook, Lawrence B. Schook, Lawrence B. Schook, Kyle M. Schachtschneider, Kyle M. Schachtschneider, Kyle M. Schachtschneider
Published 2019-02-01

The Melding of Drug Screening Platforms for Melanoma

by Gabriela Klein Couto, Natália Vieira Segatto, Thaís Larré Oliveira, Fabiana Kömmling Seixas, Kyle M. Schachtschneider, Kyle M. Schachtschneider, Kyle M. Schachtschneider, Tiago Collares
Published 2019-06-01

Transcriptional Profiling of Porcine HCC Xenografts Provides Insights Into Tumor Cell Microenvironment Signaling

by Shovik S. Patel, Amitha Sandur, Mohammed El-Kebir, Ron C. Gaba, Lawrence B. Schook, Lawrence B. Schook, Lawrence B. Schook, Kyle M. Schachtschneider, Kyle M. Schachtschneider, Kyle M. Schachtschneider
Published 2021-04-01

Effect of CRISPR Knockout of AXIN1 or ARID1A on Proliferation and Migration of Porcine Hepatocellular Carcinoma

by Lobna Elkhadragy, Kimia Dasteh Goli, William M. Totura, Maximillian J. Carlino, Maureen R. Regan, Grace Guzman, Lawrence B. Schook, Lawrence B. Schook, Lawrence B. Schook, Ron C. Gaba, Ron C. Gaba, Kyle M. Schachtschneider, Kyle M. Schachtschneider, Kyle M. Schachtschneider
Published 2022-05-01

Editorial: “Humanized” Large Animal Cancer Models: Accelerating Time and Effectiveness of Clinical Trials

by Kyle M. Schachtschneider, Gregers Jungersen, Lawrence B. Schook, Lawrence B. Schook, Dhanansayan Shanmuganayagam
Published 2019-08-01

The Oncopig as an Emerging Model to Investigate Copper Regulation in Cancer

by Alyssa L. Carlson, Jaime Carrazco-Carrillo, Aaron Loder, Lobna Elkhadragy, Kyle M. Schachtschneider, Teresita Padilla-Benavides
Published 2022-11-01

Modulation of systemic immune responses through commensal gastrointestinal microbiota.

by Kyle M Schachtschneider, Carl J Yeoman, Richard E Isaacson, Bryan A White, Lawrence B Schook, Maria Pieters
Published 2013-01-01

Oncopig Soft-Tissue Sarcomas Recapitulate Key Transcriptional Features of Human Sarcomas

by Kyle M. Schachtschneider, Yingkai Liu, Suvi Mäkeläinen, Ole Madsen, Laurie A. Rund, Martien A. M. Groenen, Lawrence B. Schook
Published 2017-06-01

The Oncopig Cancer Model as a Complementary Tool for Phenotypic Drug Discovery

by Natalia V. Segatto, Mariana H. Remião, Kyle M. Schachtschneider, Fabiana K. Seixas, Lawrence B. Schook, Lawrence B. Schook, Tiago Collares
Published 2017-12-01

Correction: Analysis of Anasplatyrhynchos genome resequencing data reveals genetic signatures of artificial selection.

by Tieshan Xu, Lihong Gu, Haopeng Yu, Xuefei Jiang, Yunsheng Zhang, Xiaohui Zhang, Guang Rong, Zhengkui Zhou, Kyle M Schachtschneider, Shuisheng Hou
Published 2019-01-01

Analysis of Anasplatyrhynchos genome resequencing data reveals genetic signatures of artificial selection.

by Tieshan Xu, Lihong Gu, Haopeng Yu, Xuefei Jiang, Yunsheng Zhang, Xiaohui Zhang, Guang Rong, Zhengkui Zhou, Kyle M Schachtschneider, Shuisheng Hou
Published 2019-01-01

TM4SF18 is aberrantly expressed in pancreatic cancer and regulates cell growth.

by Megha Singhal, Mahsa Khatibeghdami, Daniel R Principe, Georgina E Mancinelli, Kyle M Schachtschneider, Lawrence B Schook, Paul J Grippo, Sam R Grimaldo
Published 2019-01-01

Molecularly targeted photothermal ablation improves tumor specificity and immune modulation in a rat model of hepatocellular carcinoma

by Nina M. Muñoz, Crystal Dupuis, Malea Williams, Katherine Dixon, Amanda McWatters, Rony Avritscher, Richard Bouchard, Ahmed Kaseb, Kyle M. Schachtschneider, Arvind Rao, Rahul A. Sheth
Published 2020-12-01

Generation of genetically tailored porcine liver cancer cells by CRISPR/Cas9 editing

by Lobna Elkhadragy, Maureen R Regan, William M Totura, Kimia Dasteh Goli, Shovik Patel, Kelly Garcia, Matthew Stewart, Lawrence B Schook, Ron C Gaba, Kyle M Schachtschneider
Published 2021-01-01

Altered Hippocampal Epigenetic Regulation Underlying Reduced Cognitive Development in Response to Early Life Environmental Insults

by Kyle M. Schachtschneider, Michael E. Welge, Loretta S. Auvil, Sulalita Chaki, Laurie A. Rund, Ole Madsen, Monica R.P. Elmore, Rodney W. Johnson, Martien A.M. Groenen, Lawrence B. Schook
Published 2020-02-01

Genetically Induced Tumors in the Oncopig Model Invoke an Antitumor Immune Response Dominated by Cytotoxic CD8β+ T Cells and Differentiated γδ T Cells Alongside a Regulatory Respon...

by Nana H. Overgaard, Nana H. Overgaard, Daniel R. Principe, Kyle M. Schachtschneider, Jeanne Toft Jakobsen, Laurie A. Rund, Paul J. Grippo, Lawrence B. Schook, Lawrence B. Schook, Gregers Jungersen
Published 2018-06-01

A Genetic Porcine Model of Cancer.

by Lawrence B Schook, Tiago V Collares, Wenping Hu, Ying Liang, Fernanda M Rodrigues, Laurie A Rund, Kyle M Schachtschneider, Fabiana K Seixas, Kuldeep Singh, Kevin D Wells, Eric M Walters, Randall S Prather, Christopher M Counter
Published 2015-01-01

The Oncopig Cancer Model: An Innovative Large Animal Translational Oncology Platform

by Kyle M. Schachtschneider, Regina M. Schwind, Jordan Newson, Nickolas Kinachtchouk, Mark Rizko, Nasya Mendoza-Elias, Paul Grippo, Daniel R. Principe, Alex Park, Nana H. Overgaard, Gregers Jungersen, Kelly D. Garcia, Ajay V. Maker, Laurie A. Rund, Howard Ozer, Ron C. Gaba, Lawrence B. Schook, Lawrence B. Schook
Published 2017-08-01

Evolutionary signals of selection on cognition from the great tit genome and methylome

by Veronika N. Laine, Toni I. Gossmann, Kyle M. Schachtschneider, Colin J. Garroway, Ole Madsen, Koen J. F. Verhoeven, Victor de Jager, Hendrik-Jan Megens, Wesley C. Warren, Patrick Minx, Richard P. M. A. Crooijmans, Pádraic Corcoran, The Great Tit HapMap Consortium, Ben C. Sheldon, Jon Slate, Kai Zeng, Kees van Oers, Marcel E. Visser, Martien A. M. Groenen
Published 2016-01-01

Oncopig bladder cancer cells recapitulate human bladder cancer treatment responses in vitro

by Natália V. Segatto, Lucas D. Simões, Camila B. Bender, Fernanda S. Sousa, Thais L. Oliveira, Júlia D. F. Paschoal, Bruna S. Pacheco, Isadora Lopes, Fabiana K. Seixas, Aisha Qazi, Faith M. Thomas, Sulalita Chaki, Noah Robertson, Jordan Newsom, Shovik Patel, Laurie A. Rund, Luke R. Jordan, Luke R. Jordan, Courtni Bolt, Courtni Bolt, Kyle M. Schachtschneider, Lawrence B. Schook, Lawrence B. Schook, Tiago V. Collares
Published 2024-02-01