Targeting And‐1 to overcome radiation resistance in colorectal cancer

by Daniel R. Principe
Published 2022-06-01

Patients deriving long-term benefit from immune checkpoint inhibitors demonstrate conserved patterns of site-specific mutations

by Daniel R. Principe
Published 2022-07-01

Precision Medicine for <em>BRCA</em>/<em>PALB2</em>-Mutated Pancreatic Cancer and Emerging Strategies to Improve Therapeutic Responses to PARP Inhibition

by Daniel R. Principe
Published 2022-02-01

Case report: Rapid onset, ischemic-type gastritis after initiating oral iron supplementation

by Regina M. Koch, Stefan Tchernodrinski, Daniel R. Principe
Published 2022-11-01

The difficulty in translating the preclinical success of combined TGFβ and immune checkpoint inhibition to clinical trial

by Anastasia E. Metropulos, Hidayatullah G. Munshi, Daniel R. Principe
Published 2022-12-01

Chromium (VI) promotes lung cancer initiation by activating EGF/ALDH1A1 signalling

by Anastasia E. Metropulos, Jeffrey H. Becker, Daniel R. Principe
Published 2022-12-01

The Current Treatment Paradigm for Pancreatic Ductal Adenocarcinoma and Barriers to Therapeutic Efficacy

by Daniel R. Principe, Daniel R. Principe, Patrick W. Underwood, Murray Korc, Jose G. Trevino, Hidayatullah G. Munshi, Hidayatullah G. Munshi, Ajay Rana, Ajay Rana
Published 2021-07-01

Progress for Immunotherapy in Inflammatory Breast Cancer and Emerging Barriers to Therapeutic Efficacy

by Regina M. Koch, Daniel R. Principe, Jose L. Cataneo, Ajay Rana
Published 2021-05-01

Regulatory T-Cells as an Emerging Barrier to Immune Checkpoint Inhibition in Lung Cancer

by Daniel R. Principe, Daniel R. Principe, Lauren Chiec, Nisha A. Mohindra, Nisha A. Mohindra, Nisha A. Mohindra, Hidayatullah G. Munshi, Hidayatullah G. Munshi, Hidayatullah G. Munshi
Published 2021-06-01

Loss of SMAD4 Is Associated With Poor Tumor Immunogenicity and Reduced PD-L1 Expression in Pancreatic Cancer

by Daniel R. Principe, Daniel R. Principe, Patrick W. Underwood, Sandeep Kumar, Kaytlin E. Timbers, Regina M. Koch, Jose G. Trevino, Hidayatullah G. Munshi, Hidayatullah G. Munshi, Ajay Rana, Ajay Rana
Published 2022-01-01

TGFβ Signaling in the Pancreatic Tumor Microenvironment

by Daniel R. Principe, Kaytlin E. Timbers, Luke G. Atia, Regina M. Koch, Ajay Rana
Published 2021-10-01

Mitogen-Activated Protein Kinase Inhibitors and T-Cell-Dependent Immunotherapy in Cancer

by Sandeep Kumar, Daniel R. Principe, Sunil Kumar Singh, Navin Viswakarma, Gautam Sondarva, Basabi Rana, Ajay Rana
Published 2020-01-01

Leukocyte subtyping predicts for treatment failure and poor survival in anal squamous cell carcinoma

by Daniel R. Principe, Jose L. Cataneo, Kaytlin E. Timbers, Regina M. Koch, Klara Valyi-Nagy, Anders Mellgren, Ajay Rana, Gerald Gantt
Published 2022-06-01

TM4SF18 is aberrantly expressed in pancreatic cancer and regulates cell growth.

by Megha Singhal, Mahsa Khatibeghdami, Daniel R Principe, Georgina E Mancinelli, Kyle M Schachtschneider, Lawrence B Schook, Paul J Grippo, Sam R Grimaldo
Published 2019-01-01

Ets1 mediates sorafenib resistance by regulating mitochondrial ROS pathway in hepatocellular carcinoma

by Kanchan Vishnoi, Rong Ke, Navin Viswakarma, Piush Srivastava, Sandeep Kumar, Subhasis Das, Sunil Kumar Singh, Daniel R. Principe, Ajay Rana, Basabi Rana
Published 2022-07-01

HAI-1 is an independent predictor of lung cancer mortality and is required for M1 macrophage polarization.

by Stanley Borowicz, Daniel R Principe, Matthew J Dorman, Austin J McHenry, Gautam Sondarva, Sandeep Kumar, Vijayalakshmi Ananthanarayanan, Patricia E Simms, Ashley Hess, Ajay Rana
Published 2021-01-01

Preclinical Models of Pancreatic Ductal Adenocarcinoma and Their Utility in Immunotherapy Studies

by Thao N. D. Pham, Mario A. Shields, Christina Spaulding, Daniel R. Principe, Bo Li, Patrick W. Underwood, Jose G. Trevino, David J. Bentrem, Hidayatullah G. Munshi
Published 2021-01-01

Inhibition of MNKs promotes macrophage immunosuppressive phenotype to limit CD8+ T cell antitumor immunity

by Thao N.D. Pham, Christina Spaulding, Mario A. Shields, Anastasia E. Metropulos, Dhavan N. Shah, Mahmoud G. Khalafalla, Daniel R. Principe, David J. Bentrem, Hidayatullah G. Munshi
Published 2022-05-01

Genetically Induced Tumors in the Oncopig Model Invoke an Antitumor Immune Response Dominated by Cytotoxic CD8β+ T Cells and Differentiated γδ T Cells Alongside a Regulatory Respon...

by Nana H. Overgaard, Nana H. Overgaard, Daniel R. Principe, Kyle M. Schachtschneider, Jeanne Toft Jakobsen, Laurie A. Rund, Paul J. Grippo, Lawrence B. Schook, Lawrence B. Schook, Gregers Jungersen
Published 2018-06-01

The Oncopig Cancer Model: An Innovative Large Animal Translational Oncology Platform

by Kyle M. Schachtschneider, Regina M. Schwind, Jordan Newson, Nickolas Kinachtchouk, Mark Rizko, Nasya Mendoza-Elias, Paul Grippo, Daniel R. Principe, Alex Park, Nana H. Overgaard, Gregers Jungersen, Kelly D. Garcia, Ajay V. Maker, Laurie A. Rund, Howard Ozer, Ron C. Gaba, Lawrence B. Schook, Lawrence B. Schook
Published 2017-08-01