Tissue Chips in Space—Challenges and Opportunities

by Catherine K. Yeung, Paul Koenig, Stefanie Countryman, Kenneth E. Thummel, Jonathan Himmelfarb, Edward J. Kelly
Published 2020-01-01

Adapting regulatory drug‐drug interaction guidance to design clinical pharmacokinetic natural product‐drug interaction studies: A NaPDI Center recommended approach

by Emily J. Cox, Allan E. Rettie, Jashvant D. Unadkat, Kenneth E. Thummel, Jeannine S. McCune, Mary F. Paine
Published 2022-02-01

P450 Pharmacogenetics in Indigenous North American Populations

by Lindsay M. Henderson, Katrina G. Claw, Erica L. Woodahl, Renee F. Robinson, Bert B. Boyer, Wylie Burke, Kenneth E. Thummel
Published 2018-02-01

A Novel LC‐MS/MS Assay for Quantification of Des‐carboxy Prothrombin and Characterization of Warfarin‐Induced Changes

by Abdul Basit, Bhagwat Prasad, Joanne K. Estergreen, Daniel E. Sabath, Nathan Alade, David L. Veenstra, Allan E. Rettie, Kenneth E. Thummel
Published 2020-07-01

Developing a Prototype System for Integrating Pharmacogenomics Findings into Clinical Practice

by Casey Lynnette Overby, Peter Tarczy-Hornoch, Ira J. Kalet, Kenneth E. Thummel, Joe W. Smith, Guilherme Del Fiol, David Fenstermacher, Emily Beth Devine
Published 2012-11-01

Experimental pharmacology in precision medicine

by Alicja Urbaniak, Kenneth E. Thummel, Ayoade N. Alade, Allan E. Rettie, Bhagwat Prasad, Amedeo De Nicolò, Jennifer H. Martin, David N. Sheppard, Michael F. Jarvis
Published 2023-12-01

Bi-cultural dynamics for risk and protective factors for cardiometabolic health in an Alaska Native (Yup'ik) population.

by Jacques Philip, Tove K Ryman, Scarlett E Hopkins, Diane M O'Brien, Andrea Bersamin, Jeremy Pomeroy, Kenneth E Thummel, Melissa A Austin, Bert B Boyer, Kirk Dombrowski
Published 2017-01-01

Nicotine metabolism and its association with CYP2A6 genotype among Indigenous people in Alaska who smoke

by Krista R. Schaefer, Jaedon P. Avey, Michael R. Todd, Julie A. Beans, Denise A. Dillard, Laura M. Shireman, Timothy A. Thornton, Rachel F. Tyndale, Kenneth E. Thummel, Renee F. Robinson, Katrina G. Claw
Published 2021-11-01

Dietary and genetic influences on hemostasis in a Yup'ik Alaska Native population.

by Nicholas T Au, Morayma Reyes, Bert B Boyer, Scarlett E Hopkins, Jynene Black, Diane O'Brien, Alison E Fohner, Joe Yracheta, Timothy Thornton, Melissa A Austin, Wylie Burke, Kenneth E Thummel, Allan E Rettie
Published 2017-01-01

Clinical Pharmacokinetic Assessment of Kratom (<i>Mitragyna speciosa</i>), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants

by Rakshit S. Tanna, James T. Nguyen, Deena L. Hadi, Preston K. Manwill, Laura Flores-Bocanegra, Matthew E. Layton, John R. White, Nadja B. Cech, Nicholas H. Oberlies, Allan E. Rettie, Kenneth E. Thummel, Mary F. Paine
Published 2022-03-01

Functional characterization of novel rare CYP2A6 variants and potential implications for clinical outcomes

by Ahmed El‐Boraie, Julie‐Anne Tanner, Andy Z.X. Zhu, Katrina G. Claw, Bhagwat Prasad, Erin G. Schuetz, Kenneth E. Thummel, Koya Fukunaga, Taisei Mushiroda, Michiaki Kubo, Neal L. Benowitz, Caryn Lerman, Rachel F. Tyndale
Published 2022-01-01

VKORC1 and Novel CYP2C9 Variation Predict Warfarin Response in Alaska Native and American Indian People

by Lindsay M. Henderson, Renee F. Robinson, Lily Ray, Burhan A. Khan, Tianran Li, Denise A. Dillard, Brian D. Schilling, Mike Mosley, Patricia L. Janssen, Alison E. Fohner, Allan E. Rettie, Kenneth E. Thummel, Timothy A. Thornton, David L. Veenstra
Published 2019-05-01

Co‐consuming green tea with raloxifene decreases raloxifene systemic exposure in healthy adult participants

by John D. Clarke, Sabrina M. Judson, Dan‐Dan Tian, Trevor O. Kirby, Rakshit S. Tanna, Adrienn Matula‐Péntek, Miklós Horváth, Matthew E. Layton, John R. White, Nadja B. Cech, Kenneth E. Thummel, Jeannine S. McCune, Danny D. Shen, Mary F. Paine
Published 2023-10-01

Impact of a Prenatal Vitamin D Supplementation Program on Vitamin D Deficiency, Rickets and Early Childhood Caries in an Alaska Native Population

by Rosalyn J. Singleton, Gretchen M. Day, Timothy K. Thomas, Joseph A. Klejka, Christine A. Desnoyers, Melanie N. P. McIntyre, David M. Compton, Kenneth E. Thummel, Robert J. Schroth, Leanne M. Ward, Dane C. Lenaker, Rachel K. Lescher, Joseph B. McLaughlin
Published 2022-09-01

Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A4*1G allele function

by Alison E. Fohner, Rachel Dalton, Kasse Skagen, Konner Jackson, Katrina G. Claw, Scarlett E. Hopkins, Renee Robinson, Burhan A. Khan, Bhagwat Prasad, Erin G. Schuetz, Deborah A. Nickerson, Timothy A. Thornton, Denise A. Dillard, Bert B. Boyer, Kenneth E. Thummel, Erica L. Woodahl
Published 2021-07-01

Interrogation of CYP2D6 Structural Variant Alleles Improves the Correlation Between CYP2D6 Genotype and CYP2D6‐Mediated Metabolic Activity

by Rachel Dalton, Seung‐been Lee, Katrina G. Claw, Bhagwat Prasad, Brian R. Phillips, Danny D. Shen, Lai Hong Wong, Mitch Fade, Matthew G. McDonald, Maitreya J. Dunham, Douglas M. Fowler, Allan E. Rettie, Erin Schuetz, Timothy A. Thornton, Deborah A. Nickerson, Andrea Gaedigk, Kenneth E. Thummel, Erica L. Woodahl
Published 2020-01-01