Impaired CpG Demethylation in Common Variable Immunodeficiency Associates With B Cell Phenotype and Proliferation Rate

by Lucía del Pino-Molina, Javier Rodríguez-Ubreva, Juan Torres Canizales, María Coronel-Díaz, Marta Kulis, José I. Martín-Subero, José I. Martín-Subero, José I. Martín-Subero, Mirjam van der Burg, Esteban Ballestar, Eduardo López-Granados
Published 2019-04-01

DNA methylation fingerprint of neuroblastoma reveals new biological and clinical insights

by Soledad Gómez, Giancarlo Castellano, Gemma Mayol, Ana Queiros, José I. Martín-Subero, Cinzia Lavarino
Published 2015-09-01

A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions

by Elena Grossi, Ivan Raimondi, Enrique Goñi, Jovanna González, Francesco P. Marchese, Vicente Chapaprieta, José I. Martín-Subero, Shuling Guo, Maite Huarte
Published 2020-02-01

Robust CRISPR-Cas9 Genetic Editing of Primary Chronic Lymphocytic Leukemia and Mantle Cell Lymphoma Cells

by Judith Mateos-Jaimez, Maurizio Mangolini, Anna Vidal, Marta Kulis, Dolors Colomer, Elias Campo, Ingo Ringshausen, Jose I. Martin-Subero, Alba Maiques-Diaz
Published 2023-06-01

Chronic lymphocytic leukemias with trisomy 12 show a distinct DNA methylation profile linked to altered chromatin activation

by Maria Tsagiopoulou, Vicente Chapaprieta, Martí Duran-Ferrer, Theodoros Moysiadis, Fotis Psomopoulos, Panagoula Kollia, Nikos Papakonstantinou, Elias Campo, Kostas Stamatopoulos, Jose I. Martin-Subero
Published 2020-02-01

Identification of two unannotated miRNAs in classic Hodgkin lymphoma cell lines.

by Adam Ustaszewski, Julia Paczkowska, Joanna Janiszewska, Stephan H Bernhart, Julia Bein, Núria Russiñol, Martin-Leo Hansmann, Vicente Chapaprieta, José I Martín-Subero, Reiner Siebert, Sylvia Hartmann, Maciej Giefing
Published 2023-01-01

Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response

by Xabier Agirre, Cem Meydan, Yanwen Jiang, Leire Garate, Ashley S. Doane, Zhuoning Li, Akanksha Verma, Bruno Paiva, José I. Martín-Subero, Olivier Elemento, Christopher E. Mason, Felipe Prosper, Ari Melnick
Published 2019-02-01

The pattern of genomic gains in salivary gland MALT lymphomas

by Yuanping Zhou, Hongtao Ye, Jose I. Martin-Subero, Stefan Gesk, Rifat Hamoudi, Yong-Jie Lu, Rubin Wang, Janet Shipley, Reiner Siebert, Peter G. Isaacson, Ahmet Dogan, Ming-Qing Du
Published 2007-07-01

DNA hypomethylation affects cancer-related biological functions and genes relevant in neuroblastoma pathogenesis.

by Gemma Mayol, José I Martín-Subero, José Ríos, Ana Queiros, Marta Kulis, Mariona Suñol, Manel Esteller, Soledad Gómez, Idoia Garcia, Carmen de Torres, Eva Rodríguez, Patricia Galván, Jaume Mora, Cinzia Lavarino
Published 2012-01-01

Recurrent loss of the Y chromosome and homozygous deletions within the pseudoautosomal region 1: association with male predominance in mantle cell lymphoma

by Inga Nieländer, José I. Martín-Subero, Florian Wagner, Michael Baudis, Stefan Gesk, Lana Harder, Dirk Hasenclever, Wolfram Klapper, Markus Kreuz, Christiane Pott, José A. Martinez-Climent, Martin Dreyling, Norbert Arnold, Reiner Siebert
Published 2008-06-01

The hydroxymethylome of multiple myeloma identifies FAM72D as a 1q21 marker linked to proliferation

by Fabrice Chatonnet, Amandine Pignarre, Aurélien A. Sérandour, Gersende Caron, Stéphane Avner, Nicolas Robert, Alboukadel Kassambara, Audrey Laurent, Maud Bizot, Xabier Agirre, Felipe Prosper, José I. Martin-Subero, Jérôme Moreaux, Thierry Fest, Gilles Salbert
Published 2020-03-01

Detection of genomic imbalances in microdissected Hodgkin and Reed-Sternberg cells of classical Hodgkin’s lymphoma by array-based comparative genomic hybridization

by Sylvia Hartmann, José I. Martin-Subero, Stefan Gesk, Julia Hüsken, Maciej Giefing, Inga Nagel, Jennifer Riemke, Andreas Chott, Wolfram Klapper, Marie Parrens, Jean-Philippe Merlio, Ralf Küppers, Andreas Bräuninger, Reiner Siebert, Martin-Leo Hansmann
Published 2008-09-01

Cell-Cycle-Dependent Reconfiguration of the DNA Methylome during Terminal Differentiation of Human B Cells into Plasma Cells

by Gersende Caron, Mourad Hussein, Marta Kulis, Céline Delaloy, Fabrice Chatonnet, Amandine Pignarre, Stéphane Avner, Maud Lemarié, Elise A. Mahé, Núria Verdaguer-Dot, Ana C. Queirós, Karin Tarte, José I. Martín-Subero, Gilles Salbert, Thierry Fest
Published 2015-11-01

PanCancer analysis of somatic mutations in repetitive regions reveals recurrent mutations in snRNA U2

by Pablo Bousquets-Muñoz, Ander Díaz-Navarro, Ferran Nadeu, Ana Sánchez-Pitiot, Sara López-Tamargo, Shimin Shuai, Milagros Balbín, Jose M. C. Tubio, Sílvia Beà, Jose I. Martin-Subero, Ana Gutiérrez-Fernández, Lincoln D. Stein, Elías Campo, Xose S. Puente
Published 2022-03-01

Epigenomic profiling of myelofibrosis reveals widespread DNA methylation changes in enhancer elements and ZFP36L1 as a potential tumor suppressor gene that is epigenetically regula...

by Nicolás Martínez-Calle, Marien Pascual, Raquel Ordoñez, Edurne San José Enériz, Marta Kulis, Estíbaliz Miranda, Elisabeth Guruceaga, Víctor Segura, María José Larráyoz, Beatriz Bellosillo, María José Calasanz, Carles Besses, José Rifón, José I. Martín-Subero, Xabier Agirre, Felipe Prosper
Published 2019-08-01

Publisher Correction: Epigenome-wide analysis of T-cell large granular lymphocytic leukemia identifies BCL11B as a potential biomarker

by Patricia Johansson, Teresa Laguna, Julio Ossowski, Vera Pancaldi, Martina Brauser, Ulrich Dührsen, Lara Keuneke, Ana Queiros, Julia Richter, José I. Martín-Subero, Reiner Siebert, Brigitte Schlegelberger, Ralf Küppers, Jan Dürig, Eva M. Murga Penas, Enrique Carrillo-de Santa Pau, Anke K. Bergmann
Published 2023-01-01

Genetic Predisposition to Chronic Lymphocytic Leukemia Is Mediated by a BMF Super-Enhancer Polymorphism

by Radhika Kandaswamy, Georgina P. Sava, Helen E. Speedy, Sílvia Beà, José I. Martín-Subero, James B. Studd, Gabriele Migliorini, Philip J. Law, Xose S. Puente, David Martín-García, Itziar Salaverria, Jesús Gutiérrez-Abril, Carlos López-Otín, Daniel Catovsky, James M. Allan, Elías Campo, Richard S. Houlston
Published 2016-08-01

Insight into genetic predisposition to chronic lymphocytic leukemia from integrative epigenomics

by Helen E. Speedy, Renée Beekman, Vicente Chapaprieta, Giulia Orlando, Philip J. Law, David Martín-García, Jesús Gutiérrez-Abril, Daniel Catovsky, Sílvia Beà, Guillem Clot, Montserrat Puiggròs, David Torrents, Xose S. Puente, James M. Allan, Carlos López-Otín, Elias Campo, Richard S. Houlston, José I. Martín-Subero
Published 2019-08-01

DNA methylation profiling of hepatosplenic T-cell lymphoma

by Anke K. Bergmann, Virginie Fataccioli, Giancarlo Castellano, Nadine Martin-Garcia, Laura Pelletier, Ole Ammerpohl, Juri Bergmann, Jaydeep Bhat, Enrique Carrillo-de Santa Pau, José I. Martín-Subero, Andrea B. Moffitt, Alfonso Valencia, Hans-Heinrich Oberg, Daniela Wesch, Sandrine Jayne, Martin J.S. Dyer, Dieter Kabelitz, Philippe Gaulard, Reiner Siebert
Published 2019-03-01

Viral transduction of primary human lymphoma B cells reveals mechanisms of NOTCH-mediated immune escape

by Maurizio Mangolini, Alba Maiques-Diaz, Stella Charalampopoulou, Elena Gerhard-Hartmann, Johannes Bloehdorn, Andrew Moore, Giorgia Giachetti, Junyan Lu, Valar Nila Roamio Franklin, Chandra Sekkar Reddy Chilamakuri, Ilias Moutsopoulos, Andreas Rosenwald, Stephan Stilgenbauer, Thorsten Zenz, Irina Mohorianu, Clive D’Santos, Silvia Deaglio, Daniel J. Hodson, Jose I. Martin-Subero, Ingo Ringshausen
Published 2022-10-01