<i>CALR</i> but Not <i>JAK2</i> Mutations Are Associated with an Overexpression of Retinoid X Receptor Alpha in Essential Thrombocythemia

by Ana Guijarro-Hernández, Cristina Hurtado, María José Larráyoz, María José Calasanz, José Luis Vizmanos
Published 2024-04-01

NPM1 gene deletions in myelodysplastic syndromes with 5q- and complex karyotype

by Emanuele Ammatuna, Paola Panetta, Xabier Agirre, Tiziana Ottone, Serena Lavorgna, Maria José Calasanz, Francesco Lo-Coco
Published 2011-05-01

The potential effect of gender in combination with common genetic polymorphisms of drug-metabolizing enzymes on the risk of developing acute leukemia

by Pascual Bolufer, Maria Collado, Eva Barragán, José Cervera, María-José Calasanz, Dolors Colomer, José Roman-Gómez, Miguel A. Sanz
Published 2007-03-01

Bcr/Abl interferes with the Fanconi anemia/BRCA pathway: implications in the chromosomal instability of chronic myeloid leukemia cells.

by Antonio Valeri, Maria Eugenia Alonso-Ferrero, Paula Río, María Roser Pujol, José A Casado, Laura Pérez, Ariana Jacome, Xabier Agirre, Maria José Calasanz, Helmut Hanenberg, Jordi Surrallés, Felipe Prosper, Beatriz Albella, Juan A Bueren
Published 2010-12-01

The transcriptomic landscape of elderly acute myeloid leukemia identifies B7H3 and BANP as a favorable signature in high-risk patients

by Sara Villar, Sara Villar, Beñat Ariceta, Beñat Ariceta, Beñat Ariceta, Xabier Agirre, Xabier Agirre, Aura Daniela Urribarri, Rosa Ayala, David Martínez-Cuadrón, Juan Miguel Bergua, Susana Vives, Lorenzo Algarra, Mar Tormo, Pilar Martínez, Josefina Serrano, Catia Simoes, Pilar Herrera, Maria José Calasanz, Maria José Calasanz, Ana Alfonso-Piérola, Ana Alfonso-Piérola, Bruno Paiva, Bruno Paiva, Bruno Paiva, Joaquín Martínez-López, Jesús F. San Miguel, Jesús F. San Miguel, Felipe Prósper, Felipe Prósper, Pau Montesinos
Published 2022-11-01

Aberrant DNA methylation profile of chronic and transformed classic Philadelphia-negative myeloproliferative neoplasms

by Cristina Pérez, Marien Pascual, José Ignacio Martín-Subero, Beatriz Bellosillo, Victor Segura, Eric Delabesse, Sara Álvarez, María José Larrayoz, José Rifón, Juan Cruz Cigudosa, Carles Besses, María José Calasanz, Nicholas C.P. Cross, Felipe Prósper, Xabier Agirre
Published 2013-09-01

Mutation patterns of 16 genes in primary and secondary acute myeloid leukemia (AML) with normal cytogenetics.

by Marta Fernandez-Mercado, Bon Ham Yip, Andrea Pellagatti, Carwyn Davies, María José Larrayoz, Toshinori Kondo, Cristina Pérez, Sally Killick, Emma-Jane McDonald, María Dolores Odero, Xabier Agirre, Felipe Prósper, María José Calasanz, James S Wainscoat, Jacqueline Boultwood
Published 2012-01-01

Epigenomic profiling of myelofibrosis reveals widespread DNA methylation changes in enhancer elements and ZFP36L1 as a potential tumor suppressor gene that is epigenetically regula...

by Nicolás Martínez-Calle, Marien Pascual, Raquel Ordoñez, Edurne San José Enériz, Marta Kulis, Estíbaliz Miranda, Elisabeth Guruceaga, Víctor Segura, María José Larráyoz, Beatriz Bellosillo, María José Calasanz, Carles Besses, José Rifón, José I. Martín-Subero, Xabier Agirre, Felipe Prosper
Published 2019-08-01

Assessment of the clinical utility of four NGS panels in myeloid malignancies. Suggestions for NGS panel choice or design.

by Almudena Aguilera-Diaz, Iria Vazquez, Beñat Ariceta, Amagoia Mañú, Zuriñe Blasco-Iturri, Sara Palomino-Echeverría, María José Larrayoz, Ramón García-Sanz, María Isabel Prieto-Conde, María Del Carmen Chillón, Ana Alfonso-Pierola, Felipe Prosper, Marta Fernandez-Mercado, María José Calasanz
Published 2020-01-01

Frequent and simultaneous epigenetic inactivation of TP53 pathway genes in acute lymphoblastic leukemia.

by Amaia Vilas-Zornoza, Xabier Agirre, Vanesa Martín-Palanco, José Ignacio Martín-Subero, Edurne San José-Eneriz, Leire Garate, Sara Álvarez, Estíbaliz Miranda, Paula Rodríguez-Otero, José Rifón, Antonio Torres, María José Calasanz, Juan Cruz Cigudosa, José Román-Gómez, Felipe Prósper
Published 2011-02-01

TET2 mutations are associated with specific 5-methylcytosine and 5-hydroxymethylcytosine profiles in patients with chronic myelomonocytic leukemia.

by Cristina Pérez, Nicolas Martínez-Calle, José Ignacio Martín-Subero, Victor Segura, Eric Delabesse, Marta Fernandez-Mercado, Leire Garate, Sara Alvarez, José Rifon, Sara Varea, Jacqueline Boultwood, James S Wainscoat, Juan Cruz Cigudosa, María José Calasanz, Nicholas C P Cross, Felipe Prósper, Xabier Agirre
Published 2012-01-01

Assessment of Minimal Residual Disease by Next Generation Sequencing in Peripheral Blood as a Complementary Tool for Personalized Transplant Monitoring in Myeloid Neoplasms

by Paula Aguirre-Ruiz, Beñat Ariceta, María Cruz Viguria, María Teresa Zudaire, Zuriñe Blasco-Iturri, Patricia Arnedo, Almudena Aguilera-Diaz, Axier Jauregui, Amagoia Mañú, Felipe Prosper, María Carmen Mateos, Marta Fernández-Mercado, María José Larráyoz, Margarita Redondo, María José Calasanz, Iria Vázquez, Eva Bandrés
Published 2020-11-01

Quantification of cyclin D1 and D2 proteins in multiple myeloma identifies different expression patterns from those revealed by gene expression profiling

by Ignacio J. Cardona-Benavides, Irena Misiewicz-Krzeminska, Elizabeta A. Rojas, Cristina De Ramón, Antonio Sanz-Solas, Isabel Isidro, Dalia Quwaider, Aida M. López-Guerrero, Myriam Cuadrado, María-José Calasanz, Laura Rosiñol, Joaquín Martínez-López, Jesús F. San Miguel, María-Victoria Mateos, Luis A. Corchete, Norma C. Gutiérrez
Published 2023-08-01

DNA methylation profiles and their relationship with cytogenetic status in adult acute myeloid leukemia.

by Sara Alvarez, Javier Suela, Ana Valencia, Agustín Fernández, Mark Wunderlich, Xabier Agirre, Felipe Prósper, José Ignacio Martín-Subero, Alba Maiques, Francesco Acquadro, Sandra Rodriguez Perales, María José Calasanz, Jose Roman-Gómez, Reiner Siebert, James C Mulloy, José Cervera, Miguel Angel Sanz, Manel Esteller, Juan C Cigudosa
Published 2010-08-01

P848: EXPRESSION PROFILE OF BCL-2 FAMILY PROTEINS IN MULTIPLE MYELOMA.

by Cristina De Ramón Sánchez, Elizabeta A Rojas, Irena Misiewicz-Krzeminska, Ignacio J Cardona-Benavides, Myriam Cuadrado, Isabel Isidro, Maria Jose Calasanz, Ramón García-Sanz, Laura Rosiñol Dachs, Joaquín Martinez-Lopez, Joan Baldé, Juan J Lahuerta, Jesus F San Miguel, Maria-Victoria Mateos, Luis A Corchete, Norma Carmen Gutierrez Gutierrez
Published 2023-08-01

Epigenetic activation of SOX11 in lymphoid neoplasms by histone modifications.

by Maria Carmela Vegliante, Cristina Royo, Jara Palomero, Itziar Salaverria, Balazs Balint, Idoia Martín-Guerrero, Xabier Agirre, Amaia Lujambio, Julia Richter, Silvia Xargay-Torrent, Silvia Bea, Luis Hernandez, Anna Enjuanes, María José Calasanz, Andreas Rosenwald, German Ott, José Roman-Gomez, Felipe Prosper, Manel Esteller, Pedro Jares, Reiner Siebert, Elias Campo, José I Martín-Subero, Virginia Amador
Published 2011-01-01

Chromosome banding analysis and genomic microarrays are both useful but not equivalent methods for genomic complexity risk stratification in chronic lymphocytic leukemia patients

by Silvia Ramos-Campoy, Anna Puiggros, Sílvia Beà, Sandrine Bougeon, María José Larráyoz, Dolors Costa, Helen Parker, Gian Matteo Rigolin, Margarita Ortega, María Laura Blanco, Rosa Collado, Rocío Salgado, Tycho Baumann, Eva Gimeno, Carolina Moreno, Francesc Bosch, Xavier Calvo, María José Calasanz, Antonio Cuneo, Jonathan C. Strefford, Florence Nguyen-Khac, David Oscier, Claudia Haferlach, Jacqueline Schoumans, Blanca Espinet
Published 2021-03-01

<i>TP53</i> Abnormalities Are Underlying the Poor Outcome Associated with Chromothripsis in Chronic Lymphocytic Leukemia Patients with Complex Karyotype

by Silvia Ramos-Campoy, Anna Puiggros, Joanna Kamaso, Sílvia Beà, Sandrine Bougeon, María José Larráyoz, Dolors Costa, Helen Parker, Gian Matteo Rigolin, María Laura Blanco, Rosa Collado, Idoya Ancín, Rocío Salgado, Marco A. Moro-García, Tycho Baumann, Eva Gimeno, Carol Moreno, Marta Salido, Xavier Calvo, María José Calasanz, Antonio Cuneo, Florence Nguyen-Khac, David Oscier, Claudia Haferlach, Jonathan C. Strefford, Jacqueline Schoumans, Blanca Espinet
Published 2022-07-01

Unsupervised machine learning improves risk stratification in newly diagnosed multiple myeloma: an analysis of the Spanish Myeloma Group

by Adrian Mosquera Orgueira, Marta Sonia González Pérez, Jose Diaz Arias, Laura Rosiñol, Albert Oriol, Ana Isabel Teruel, Joaquin Martinez Lopez, Luis Palomera, Miguel Granell, Maria Jesus Blanchard, Javier de la Rubia, Ana López de la Guia, Rafael Rios, Anna Sureda, Miguel Teodoro Hernandez, Enrique Bengoechea, María José Calasanz, Norma Gutierrez, Maria Luis Martin, Joan Blade, Juan-Jose Lahuerta, Jesús San Miguel, Maria Victoria Mateos, the PETHEMA/GEM Cooperative Group
Published 2022-04-01

NGS-Based Molecular Karyotyping of Multiple Myeloma: Results from the GEM12 Clinical Trial

by Juan Manuel Rosa-Rosa, Isabel Cuenca, Alejandro Medina, Iria Vázquez, Andrea Sánchez-delaCruz, Natalia Buenache, Ricardo Sánchez, Cristina Jiménez, Laura Rosiñol, Norma C. Gutiérrez, Yanira Ruiz-Heredia, Santiago Barrio, Albert Oriol, Maria-Luisa Martin-Ramos, María-Jesús Blanchard, Rosa Ayala, Rafael Ríos-Tamayo, Anna Sureda, Miguel-Teodoro Hernández, Javier de la Rubia, Gorka Alkorta-Aranburu, Xabier Agirre, Joan Bladé, María-Victoria Mateos, Juan-José Lahuerta, Jesús F. San-Miguel, María-José Calasanz, Ramón Garcia-Sanz, Joaquín Martínez-Lopez
Published 2022-10-01