Yeast silent mating type loci form heterochromatic clusters through silencer protein-dependent long-range interactions.

by Adriana Miele, Kerstin Bystricky, Job Dekker
Published 2009-05-01

Linker histone H1.8 inhibits chromatin binding of condensins and DNA topoisomerase II to tune chromosome length and individualization

by Pavan Choppakatla, Bastiaan Dekker, Erin E Cutts, Alessandro Vannini, Job Dekker, Hironori Funabiki
Published 2021-08-01

Mitotic chromosomes scale to nuclear-cytoplasmic ratio and cell size in Xenopus

by Coral Y Zhou, Bastiaan Dekker, Ziyuan Liu, Hilda Cabrera, Joel Ryan, Job Dekker, Rebecca Heald
Published 2023-04-01

Loops, topologically associating domains, compartments, and territories are elastic and robust to dramatic nuclear volume swelling

by Jacob T. Sanders, Rosela Golloshi, Priyojit Das, Yang Xu, Peyton H. Terry, Darrian G. Nash, Job Dekker, Rachel Patton McCord
Published 2022-03-01

Large domains of heterochromatin direct the formation of short mitotic chromosome loops

by Maximilian H Fitz-James, Pin Tong, Alison L Pidoux, Hakan Ozadam, Liyan Yang, Sharon A White, Job Dekker, Robin C Allshire
Published 2020-09-01

Nutritional control regulates symbiont proliferation and life history in coral-dinoflagellate symbiosis

by Guoxin Cui, Yi Jin Liew, Migle K. Konciute, Ye Zhan, Shiou-Han Hung, Jana Thistle, Lucia Gastoldi, Sebastian Schmidt-Roach, Job Dekker, Manuel Aranda
Published 2022-05-01

The Conformation of Yeast Chromosome III Is Mating Type Dependent and Controlled by the Recombination Enhancer

by Jon-Matthew Belton, Bryan R. Lajoie, Sylvain Audibert, Sylvain Cantaloube, Imen Lassadi, Isabelle Goiffon, Davide Baù, Marc A. Marti-Renom, Kerstin Bystricky, Job Dekker
Published 2015-12-01

Inner nuclear protein Matrin-3 coordinates cell differentiation by stabilizing chromatin architecture

by Hye Ji Cha, Özgün Uyan, Yan Kai, Tianxin Liu, Qian Zhu, Zuzana Tothova, Giovanni A. Botten, Jian Xu, Guo-Cheng Yuan, Job Dekker, Stuart H. Orkin
Published 2021-10-01

Extremely Long-Range Chromatin Loops Link Topological Domains to Facilitate a Diverse Antibody Repertoire

by Lindsey Montefiori, Robert Wuerffel, Damian Roqueiro, Bryan Lajoie, Changying Guo, Tatiana Gerasimova, Supriyo De, William Wood, Kevin G. Becker, Job Dekker, Jie Liang, Ranjan Sen, Amy L. Kenter
Published 2016-02-01

Highly structured homolog pairing reflects functional organization of the Drosophila genome

by Jumana AlHaj Abed, Jelena Erceg, Anton Goloborodko, Son C. Nguyen, Ruth B. McCole, Wren Saylor, Geoffrey Fudenberg, Bryan R. Lajoie, Job Dekker, Leonid A. Mirny, C.-ting Wu
Published 2019-10-01

<i>rad21</i> Is Involved in Corneal Stroma Development by Regulating Neural Crest Migration

by Bi Ning Zhang, Yu Liu, Qichen Yang, Pui Ying Leung, Chengdong Wang, Thomas Chi Bun Wong, Clement C. Tham, Sun On Chan, Chi Pui Pang, Li Jia Chen, Job Dekker, Hui Zhao, Wai Kit Chu
Published 2020-10-01

The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome

by Michal R. Gdula, Tatyana B. Nesterova, Greta Pintacuda, Jonathan Godwin, Ye Zhan, Hakan Ozadam, Michael McClellan, Daniella Moralli, Felix Krueger, Catherine M. Green, Wolf Reik, Skirmantas Kriaucionis, Edith Heard, Job Dekker, Neil Brockdorff
Published 2019-01-01

Measuring the reproducibility and quality of Hi-C data

by Galip Gürkan Yardımcı, Hakan Ozadam, Michael E. G. Sauria, Oana Ursu, Koon-Kiu Yan, Tao Yang, Abhijit Chakraborty, Arya Kaul, Bryan R. Lajoie, Fan Song, Ye Zhan, Ferhat Ay, Mark Gerstein, Anshul Kundaje, Qunhua Li, James Taylor, Feng Yue, Job Dekker, William S. Noble
Published 2019-03-01

The genome-wide multi-layered architecture of chromosome pairing in early Drosophila embryos

by Jelena Erceg, Jumana AlHaj Abed, Anton Goloborodko, Bryan R. Lajoie, Geoffrey Fudenberg, Nezar Abdennur, Maxim Imakaev, Ruth B. McCole, Son C. Nguyen, Wren Saylor, Eric F. Joyce, T. Niroshini Senaratne, Mohammed A. Hannan, Guy Nir, Job Dekker, Leonid A. Mirny, C.-ting Wu
Published 2019-10-01

Disease-causing 7.4 kb cis-regulatory deletion disrupting conserved non-coding sequences and their interaction with the FOXL2 promotor: implications for mutation screening.

by Barbara D'haene, Catia Attanasio, Diane Beysen, Josée Dostie, Edmond Lemire, Philippe Bouchard, Michael Field, Kristie Jones, Birgit Lorenz, Björn Menten, Karen Buysse, Filip Pattyn, Marc Friedli, Catherine Ucla, Colette Rossier, Carine Wyss, Frank Speleman, Anne De Paepe, Job Dekker, Stylianos E Antonarakis, Elfride De Baere
Published 2009-06-01

Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment

by Vishnu Dileep, Korey A. Wilson, Claire Marchal, Xiaowen Lyu, Peiyao A. Zhao, Ben Li, Axel Poulet, Daniel A. Bartlett, Juan Carlos Rivera-Mulia, Zhaohui S. Qin, Allan J. Robins, Thomas C. Schulz, Michael J. Kulik, Rachel Patton McCord, Job Dekker, Stephen Dalton, Victor G. Corces, David M. Gilbert
Published 2019-07-01

Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML

by Zuzana Tothova, Anne-Laure Valton, Rebecca A. Gorelov, Mounica Vallurupalli, John M. Krill-Burger, Amie Holmes, Catherine C. Landers, J. Erika Haydu, Edyta Malolepsza, Christina Hartigan, Melanie Donahue, Katerina D. Popova, Sebastian Koochaki, Sergey V. Venev, Jeanne Rivera, Edwin Chen, Kasper Lage, Monica Schenone, Alan D. D’Andrea, Steven A. Carr, Elizabeth A. Morgan, Job Dekker, Benjamin L. Ebert
Published 2021-02-01

Evidence for transcript networks composed of chimeric RNAs in human cells.

by Sarah Djebali, Julien Lagarde, Philipp Kapranov, Vincent Lacroix, Christelle Borel, Jonathan M Mudge, Cédric Howald, Sylvain Foissac, Catherine Ucla, Jacqueline Chrast, Paolo Ribeca, David Martin, Ryan R Murray, Xinping Yang, Lila Ghamsari, Chenwei Lin, Ian Bell, Erica Dumais, Jorg Drenkow, Michael L Tress, Josep Lluís Gelpí, Modesto Orozco, Alfonso Valencia, Nynke L van Berkum, Bryan R Lajoie, Marc Vidal, John Stamatoyannopoulos, Philippe Batut, Alex Dobin, Jennifer Harrow, Tim Hubbard, Job Dekker, Adam Frankish, Kourosh Salehi-Ashtiani, Alexandre Reymond, Stylianos E Antonarakis, Roderic Guigó, Thomas R Gingeras
Published 2012-01-01

Multi-omics comparison of malignant and normal uveal melanocytes reveals molecular features of uveal melanoma

by David Gentien, Elnaz Saberi-Ansari, Nicolas Servant, Ariane Jolly, Pierre de la Grange, Fariba Némati, Géraldine Liot, Simon Saule, Aurélie Teissandier, Deborah Bourc’his, Elodie Girard, Jennifer Wong, Julien Masliah-Planchon, Erkan Narmanli, Yuanlong Liu, Emma Torun, Rebecca Goulancourt, Manuel Rodrigues, Laure Villoing Gaudé, Cécile Reyes, Matéo Bazire, Thomas Chenegros, Emilie Henry, Audrey Rapinat, Mylene Bohec, Sylvain Baulande, Radhia M’kacher, Eric Jeandidier, André Nicolas, Giovanni Ciriello, Raphael Margueron, Didier Decaudin, Nathalie Cassoux, Sophie Piperno-Neumann, Marc-Henri Stern, Johan Harmen Gibcus, Job Dekker, Edith Heard, Sergio Roman-Roman, Joshua J. Waterfall
Published 2023-09-01

Polymer Models of Yeast S. cerevisiae Genome Organization

by Fudenberg, Geoffrey, Belton, Jon-Matthew, Goloborodko, Anton, Imakaev, Maxim, Dekker, Job, Mirny, Leonid Alex
Published 2014