Functional characterization of human cancer-derived TRKB mutations.

by Thomas R Geiger, Ji-Ying Song, Aranzazu Rosado, Daniel S Peeper
Published 2011-02-01

Absence of integrin α3β1 promotes the progression of HER2-driven breast cancer in vivo

by Veronika Ramovs, Pablo Secades, Ji-Ying Song, Bram Thijssen, Maaike Kreft, Arnoud Sonnenberg
Published 2019-05-01

Dermal Delivery of Constructs Encoding Cre Recombinase to Induce Skin Tumors in PtenLoxP/LoxP;BrafCA/+ Mice

by Marcel A. Deken, Ji-Ying Song, Jules Gadiot, Adriaan D. Bins, Paula Kroon, Inge Verbrugge, Christian U. Blank
Published 2016-12-01

Gene expression regulation by the Chromodomain helicase DNA-binding protein 9 (CHD9) chromatin remodeler is dispensable for murine development.

by Andrej Alendar, Jan-Paul Lambooij, Rajith Bhaskaran, Cesare Lancini, Ji-Ying Song, Huub van Vugt, Margriet Snoek, Anton Berns
Published 2020-01-01

A C57BL/6J Fancg-KO Mouse Model Generated by CRISPR/Cas9 Partially Captures the Human Phenotype

by Ronak Shah, Paul C. M. van den Berk, Colin E. J. Pritchard, Ji-Ying Song, Maaike Kreft, Bas Pilzecker, Heinz Jacobs
Published 2023-07-01

Evaluation of acute esophageal radiation-induced damage using magnetic resonance imaging: a feasibility study in mice

by Pouya Jelvehgaran, Jeffrey D. Steinberg, Artem Khmelinskii, Gerben Borst, Ji-Ying Song, Niels de Wit, Daniel M. de Bruin, Marcel van Herk
Published 2019-10-01

FGFR1 Oncogenic Activation Reveals an Alternative Cell of Origin of SCLC in Rb1/p53 Mice

by Giustina Ferone, Ji-Ying Song, Oscar Krijgsman, Jan van der Vliet, Miranda Cozijnsen, Ekaterina A. Semenova, David J. Adams, Daniel Peeper, Anton Berns
Published 2020-03-01

Towards an understanding of C9orf82 protein/CAAP1 function.

by Muhammad Assad Aslam, Mir Farshid Alemdehy, Colin E J Pritchard, Ji-Ying Song, Fitriari Izzatunnisa Muhaimin, Ruud H Wijdeven, Ivo J Huijbers, Jacques Neefjes, Heinz Jacobs
Published 2019-01-01

A natural WNT signaling variant potently synergizes with Cdkn2ab loss in skin carcinogenesis

by Paul Krimpenfort, Margriet Snoek, Jan-Paul Lambooij, Ji-Ying Song, Robin van der Weide, Rajith Bhaskaran, Hans Teunissen, David J. Adams, Elzo de Wit, Anton Berns
Published 2019-03-01

No relation between docetaxel administration route and high‐grade diarrhea incidence

by Jeroen J. M. A. Hendrikx, Frederik E. Stuurman, Ji‐Ying Song, Vincent A. deWeger, Jurjen S. Lagas, Hilde Rosing, Jos H. Beijnen, Alfred H. Schinkel, Jan H. M. Schellens, Serena Marchetti
Published 2020-08-01

Tumor Heterogeneity Underlies Differential Cisplatin Sensitivity in Mouse Models of Small-Cell Lung Cancer

by Franziska Böttger, Ekaterina A. Semenova, Ji-Ying Song, Giustina Ferone, Jan van der Vliet, Miranda Cozijnsen, Rajith Bhaskaran, Lorenzo Bombardelli, Sander R. Piersma, Thang V. Pham, Connie R. Jimenez, Anton Berns
Published 2019-06-01

Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma

by Sarah A. Best, Sheryl Ding, Ariena Kersbergen, Xueyi Dong, Ji-Ying Song, Yi Xie, Boris Reljic, Kaiming Li, James E. Vince, Vivek Rathi, Gavin M. Wright, Matthew E. Ritchie, Kate D. Sutherland
Published 2019-09-01

GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors.

by Bart A Westerman, Marleen Blom, Ellen Tanger, Martin van der Valk, Ji-Ying Song, Marije van Santen, Jules Gadiot, Paulien Cornelissen-Steijger, John Zevenhoven, Haydn M Prosser, Anthony Uren, Eleonora Aronica, Maarten van Lohuizen
Published 2012-01-01

Interplay of OATP1A/1B/2B1 uptake transporters and ABCB1 and ABCG2 efflux transporters in the handling of bilirubin and drugs

by Wenlong Li, Rolf W. Sparidans, Yaogeng Wang, Margarida L.F. Martins, Dirk R. de Waart, Olaf van Tellingen, Ji-Ying Song, Maria C. Lebre, Stéphanie van Hoppe, Els Wagenaar, Jos H. Beijnen, Alfred H. Schinkel
Published 2024-06-01

Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients

by Xiaohang Qiao, Sabina Y. van der Zanden, Xiaoyang Li, Minkang Tan, Yunxiang Zhang, Ji-Ying Song, Merle A. van Gelder, Feija L. Hamoen, Lennert Janssen, Charlotte L. Zuur, Baoxu Pang, Olaf van Tellingen, Junmin Li, Jacques Neefjes
Published 2024-06-01

Natural deletion of mouse carboxylesterases Ces1c/d/e impacts drug metabolism and metabolic syndrome development

by Changpei Gan, Jing Wang, Yaogeng Wang, Alejandra Martínez-Chávez, Michel Hillebrand, Niels de Vries, Joke Beukers, Maria C. Lebre, Els Wagenaar, Hilde Rosing, Sjoerd Klarenbeek, Onno B. Bleijerveld, Ji-Ying Song, Maarten Altelaar, Jos H. Beijnen, Alfred H. Schinkel
Published 2023-08-01

Parallel In Vivo and In Vitro Melanoma RNAi Dropout Screens Reveal Synthetic Lethality between Hypoxia and DNA Damage Response Inhibition

by Patricia A. Possik, Judith Müller, Carmen Gerlach, Juliana C.N. Kenski, Xinyao Huang, Aida Shahrabi, Oscar Krijgsman, Ji-Ying Song, Marjon A. Smit, Bram Gerritsen, Cor Lieftink, Kristel Kemper, Magali Michaut, Roderick L. Beijersbergen, Lodewyk Wessels, Ton N. Schumacher, Daniel S. Peeper
Published 2014-11-01

Rational combination of SHP2 and mTOR inhibition for the treatment of hepatocellular carcinoma

by Antonio Mulero‐Sánchez, Christel F. A. Ramirez, Aimée duChatinier, Hui Wang, Sofie J. I. Koomen, Ji‐Ying Song, Marnix H. P. deGroot, Cor Lieftink, Astrid Bosma, Artur Burylo, Olaf vanTellingen, Roderick L. Beijersbergen, Cun Wang, Leila Akkari, René Bernards, Sara Mainardi
Published 2023-06-01

XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data

by Roelof J. C. Kluin, Kristel Kemper, Thomas Kuilman, Julian R. de Ruiter, Vivek Iyer, Josep V. Forment, Paulien Cornelissen-Steijger, Iris de Rink, Petra ter Brugge, Ji-Ying Song, Sjoerd Klarenbeek, Ultan McDermott, Jos Jonkers, Arno Velds, David J. Adams, Daniel S. Peeper, Oscar Krijgsman
Published 2018-10-01

Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity.

by Ziva Pogacar, Jackie L Johnson, Lenno Krenning, Giulia De Conti, Fleur Jochems, Cor Lieftink, Arno Velds, Leyma Wardak, Kelvin Groot, Arnout Schepers, Liqin Wang, Ji-Ying Song, Marieke van de Ven, Olaf van Tellingen, Rene H Medema, Roderick L Beijersbergen, Rene Bernards, Rodrigo Leite de Oliveira
Published 2022-01-01