1201 SGLT2 inhibitors modulate inflammation and germinal centers in lupus

by Javier Rangel-Moreno, Mary O’Connell, Jennifer H Anolik, Maria de la Luz Garcia-Hernandez, Daria Krenitsky, Maria Fernanda Ossa-Echeverri, Mark Lusco, John Looney
Published 2024-05-01

Failure of B Cell Tolerance in CVID

by Christopher T. Richardson, Christopher T. Richardson, Maria A. Slack, Maria A. Slack, Gitika Dhillon, Carolina Z. Marcus, Jennifer Barnard, Arumugam Palanichamy, Ignacio Sanz, Richard John Looney, Jennifer H. Anolik
Published 2019-12-01

B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation

by Wen Sun, Nida Meednu, Alexander Rosenberg, Javier Rangel-Moreno, Victor Wang, Jason Glanzman, Teresa Owen, Xichao Zhou, Hengwei Zhang, Brendan F. Boyce, Jennifer H. Anolik, Lianping Xing
Published 2018-12-01

Expansion of Activated Peripheral Blood Memory B Cells in Rheumatoid Arthritis, Impact of B Cell Depletion Therapy, and Biomarkers of Response.

by Diana G Adlowitz, Jennifer Barnard, Jamie N Biear, Christopher Cistrone, Teresa Owen, Wensheng Wang, Arumugam Palanichamy, Ezinma Ezealah, Debbie Campbell, Chungwen Wei, R John Looney, Inaki Sanz, Jennifer H Anolik
Published 2015-01-01

Multi-omics analysis identifies IgG2b class-switching with ALCAM-CD6 co-stimulation in joint-draining lymph nodes during advanced inflammatory-erosive arthritis

by H. Mark Kenney, H. Mark Kenney, Javier Rangel-Moreno, Yue Peng, Yue Peng, Kiana L. Chen, Kiana L. Chen, Jennifer Bruno, Jennifer Bruno, Abdul Embong, Elizabeth Pritchett, Jeffrey I. Fox, Enrique Becerril-Villanueva, Armando Gamboa-Domínguez, Sally Quataert, Sally Quataert, Gowrishankar Muthukrishnan, Gowrishankar Muthukrishnan, Gowrishankar Muthukrishnan, Ronald W. Wood, Ronald W. Wood, Ronald W. Wood, Ronald W. Wood, Benjamin D. Korman, Benjamin D. Korman, Jennifer H. Anolik, Jennifer H. Anolik, Jennifer H. Anolik, Lianping Xing, Lianping Xing, Christopher T. Ritchlin, Christopher T. Ritchlin, Edward M. Schwarz, Edward M. Schwarz, Edward M. Schwarz, Edward M. Schwarz, Edward M. Schwarz, Edward M. Schwarz, Chia-Lung Wu, Chia-Lung Wu
Published 2023-08-01

Dynamic spectrum of ectopic lymphoid B cell activation and hypermutation in the RA synovium characterized by NR4A nuclear receptor expression

by Nida Meednu, Javier Rangel-Moreno, Fan Zhang, Katherine Escalera-Rivera, Elisa Corsiero, Edoardo Prediletto, Edward DiCarlo, Susan Goodman, Laura T. Donlin, Soumya Raychauduri, Michele Bombardieri, Costantino Pitzalis, Dana E. Orange, Andrew McDavid, Jennifer H. Anolik
Published 2022-05-01

The chromatin landscape of pathogenic transcriptional cell states in rheumatoid arthritis

by Kathryn Weinand, Saori Sakaue, Aparna Nathan, Anna Helena Jonsson, Fan Zhang, Gerald F. M. Watts, Majd Al Suqri, Zhu Zhu, Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network, Deepak A. Rao, Jennifer H. Anolik, Michael B. Brenner, Laura T. Donlin, Kevin Wei, Soumya Raychaudhuri
Published 2024-05-01

Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium

by Garrett Dunlap, Aaron Wagner, Nida Meednu, Ruoqiao Wang, Fan Zhang, Jabea Cyril Ekabe, Anna Helena Jonsson, Kevin Wei, Saori Sakaue, Aparna Nathan, Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network, Vivian P. Bykerk, Laura T. Donlin, Susan M. Goodman, Gary S. Firestein, David L. Boyle, V. Michael Holers, Larry W. Moreland, Darren Tabechian, Costantino Pitzalis, Andrew Filer, Soumya Raychaudhuri, Michael B. Brenner, Juilee Thakar, Andrew McDavid, Deepak A. Rao, Jennifer H. Anolik
Published 2024-06-01

1009 In-depth analysis of myeloid cell subsets in lupus nephritis kidneys provides insights into disease mechanisms: lessons from the accelerating medicines partnership (AMP) in RA...

by Richard Furie, Joel M Guthridge, Judith A James, Maria Dall’Era, Michelle A Petri, Chaim Putterman, Jill P Buyon, Diane L Kamen, Betty Diamond, David Wofsy, Soumya Raychaudhuri, Thomas Tuschl, Jennifer Grossman, Peter M Izmirly, Qian Xiao, Nir Hacohen, Kenneth C Kalunian, Michael B Brenner, Mariko Ishimori, H Michael Belmont, Robert Clancy, ANNE DAVIDSON, Matthias Kretzler, Michael Weisman, Celine C Berthier, Andrea Fava, Jennifer L Barnas, Jennifer H Anolik, Paul J Hoover, Deepak A Rao, Arnon Arazi, William Apruzzese, Fernanda Payan-Schober, Joseph Mears, Saori Sakaue, James Lederer, Michael Peters, Tony Jones, Thomas M Eisenhaure, Siddarth Gurajala, Derek Fine, David A Hildeman, Steve Woodle, Maureen A McMahon, Jeffery Hodgin
Published 2024-05-01

1107 Immune cell heterogeneity in lupus nephritis kidneys and its relation to histopathological features: lessons from the accelerating medicines partnership (AMP) in SLE Consortiu...

by Richard Furie, Joel M Guthridge, Judith A James, Maria Dall’Era, Michelle A Petri, Chaim Putterman, Jill P Buyon, Diane L Kamen, Betty Diamond, David Wofsy, Soumya Raychaudhuri, Thomas Tuschl, Jennifer Grossman, Peter M Izmirly, Qian Xiao, Nir Hacohen, Kenneth C Kalunian, Michael B Brenner, Mariko Ishimori, H Michael Belmont, Robert Clancy, ANNE DAVIDSON, Matthias Kretzler, Michael Weisman, Celine C Berthier, Andrea Fava, Jennifer L Barnas, Jennifer H Anolik, Paul J Hoover, Deepak A Rao, Arnon Arazi, William Apruzzese, Fernanda Payan-Schober, Saori Sakaue, James Lederer, Michael Peters, Tony Jones, Jospeh Mears, Thomas M Eisenhaure, Siddarth Gurajala, Derek Fine, David A Hildeman, Steve Woodle, Maureen A McMahon, Jeffery Hodgin
Published 2022-12-01

Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue

by Laura T. Donlin, Deepak A. Rao, Kevin Wei, Kamil Slowikowski, Mandy J. McGeachy, Jason D. Turner, Nida Meednu, Fumitaka Mizoguchi, Maria Gutierrez-Arcelus, David J. Lieb, Joshua Keegan, Kaylin Muskat, Joshua Hillman, Cristina Rozo, Edd Ricker, Thomas M. Eisenhaure, Shuqiang Li, Edward P. Browne, Adam Chicoine, Danielle Sutherby, Akiko Noma, Accelerating Medicines Partnership RA/SLE Network, Chad Nusbaum, Stephen Kelly, Alessandra B. Pernis, Lionel B. Ivashkiv, Susan M. Goodman, William H. Robinson, Paul J. Utz, James A. Lederer, Ellen M. Gravallese, Brendan F. Boyce, Nir Hacohen, Costantino Pitzalis, Peter K. Gregersen, Gary S. Firestein, Soumya Raychaudhuri, Larry W. Moreland, V. Michael Holers, Vivian P. Bykerk, Andrew Filer, David L. Boyle, Michael B. Brenner, Jennifer H. Anolik
Published 2018-07-01

1012 Deep peripheral blood immunophenotyping identifies a subgroup of lupus nephritis patients characterized by high type 1 interferon signaling, persistent activated immune cells...

by Richard Furie, Judith A James, Maria Dall’Era, Michelle A Petri, Chaim Putterman, Peter Izmirly, Jill P Buyon, Diane L Kamen, Betty Diamond, David Wofsy, Soumya Raychaudhuri, Jennifer Grossman, Fan Zhang, Jun Inamo, Nir Hacohen, Alice Horisberger, Kenneth C Kalunian, Michael B Brenner, Mariko Ishimori, David Hildeman, Robert Clancy, ANNE DAVIDSON, Matthias Kretzler, Michael Weisman, Celine C Berthier, Andrea Fava, Takanori Sasaki, Jennifer L Barnas, Jennifer H Anolik, Paul J Hoover, Deepak A Rao, Joshua Keegan, James A Lederer, Joel Guthridge, Michael Belmont, Arnon Arazi, William Apruzzese, Fernanda Payan-Schober, Jeffrey Hodgin, Thomas M Eisenhaure, Steve Woodle, Maureen A McMahon, Ekaterina Murzin, Katie Preisinger, Alec Griffith, Kaitlyn Howard, Tusharkanti Ghosh, Rebecca Beuschel, John Pulford, Brandon Hancock, Maria Gutierrez-Arcelus
Published 2024-05-01