Distinct DNA Methylation Patterns of Rheumatoid Arthritis Peripheral Blood and Synovial Tissue T Cells

by Rizi Ai, David L. Boyle, Wei Wang, Gary S. Firestein
Published 2021-03-01

Improving Transcriptome Fidelity Following Synovial Tissue Disaggregation

by David L. Boyle, Edward B. Prideaux, Joshua Hillman, Wei Wang, Gary S. Firestein
Published 2022-08-01

Joint Location–Specific JAK‐STAT Signaling in Rheumatoid Arthritis Fibroblast‐like Synoviocytes

by Deepa Hammaker, Gyrid Nygaard, Amanda Kuhs, Rizi Ai, David L. Boyle, Wei Wang, Gary S. Firestein
Published 2019-12-01

Correction: Integrative Omics Analysis of Rheumatoid Arthritis Identifies Non-Obvious Therapeutic Targets.

by John W Whitaker, David L Boyle, Beatrix Bartok, Scott T Ball, Steffen Gay, Wei Wang, Gary S Firestein
Published 2015-01-01

Integrative omics analysis of rheumatoid arthritis identifies non-obvious therapeutic targets.

by John W Whitaker, David L Boyle, Beatrix Bartok, Scott T Ball, Steffen Gay, Wei Wang, Gary S Firestein
Published 2015-01-01

Lipopolysaccharide Exposure Differentially Alters Plasma and Brain Inflammatory Markers in Adult Male and Female Rats

by Hannah A. Nonoguchi, Timothy Wee Shang Kouo, Sandhya Kortagere, Joshua Hillman, David L. Boyle, Chitra D. Mandyam
Published 2022-07-01

Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processes

by Rizi Ai, Deepa Hammaker, David L. Boyle, Rachel Morgan, Alice M. Walsh, Shicai Fan, Gary S. Firestein, Wei Wang
Published 2016-06-01

Correction: Differential Roles of MAPK Kinases MKK3 and MKK6 in Osteoclastogenesis and Bone Loss.

by David L. Boyle, Deepa Hammaker, Meghan Edgar, Mario M. Zaiss, Stefan Teufel, Jean Pierre David, Georg Schett, Gary S. Firestein
Published 2014-01-01

Regulation of peripheral inflammation by spinal p38 MAP kinase in rats.

by David L Boyle, Toni L Jones, Deepa Hammaker, Camille I Svensson, Sanna Rosengren, Salvatore Albani, Linda Sorkin, Gary S Firestein
Published 2006-09-01

Differential roles of MAPK kinases MKK3 and MKK6 in osteoclastogenesis and bone loss.

by David L Boyle, Deepa Hammaker, Meghan Edgar, Mario M Zaiss, Stefan Teufel, Jean Pierre David, Georg Schett, Gary S Firestein
Published 2014-01-01

Joint-specific regulation of homeobox D10 expression in rheumatoid arthritis fibroblast-like synoviocytes

by Hyeonjeong Lee, Camilla R. L. Machado, Deepa Hammaker, Eunice Choi, Edward B. Prideaux, Wei Wang, David L. Boyle, Gary S. Firestein
Published 2024-01-01

Joint-specific regulation of homeobox D10 expression in rheumatoid arthritis fibroblast-like synoviocytes.

by Hyeonjeong Lee, Camilla R L Machado, Deepa Hammaker, Eunice Choi, Edward B Prideaux, Wei Wang, David L Boyle, Gary S Firestein
Published 2024-01-01

Crosstalk between CD4 T cells and synovial fibroblasts from human arthritic joints promotes hyaluronan-dependent leukocyte adhesion and inflammatory cytokine expression in vitro

by Inkyung Kang, Christian Hundhausen, Stephen P. Evanko, Prasanthi Malapati, Gail Workman, Christina K. Chan, Cliff Rims, Gary S. Firestein, David L. Boyle, Kevin M. MacDonald, Jane H. Buckner, Thomas N. Wight
Published 2022-06-01

Systems-biology analysis of rheumatoid arthritis fibroblast-like synoviocytes implicates cell line-specific transcription factor function

by Richard I. Ainsworth, Deepa Hammaker, Gyrid Nygaard, Cecilia Ansalone, Camilla Machado, Kai Zhang, Lina Zheng, Lucy Carrillo, Andre Wildberg, Amanda Kuhs, Mattias N. D. Svensson, David L. Boyle, Gary S. Firestein, Wei Wang
Published 2022-10-01

Caspase‐8 Variant G Regulates Rheumatoid Arthritis Fibroblast‐Like Synoviocyte Aggressive Behavior

by Cecilia Ansalone, Richard I. Ainsworth, Gyrid Nygaard, Rizi Ai, Edward B. Prideaux, Deepa Hammaker, Narayanan B. Perumal, Ken Weichert, Frances Tung, Lalitha Kodandapani, J. Michael Sauder, Elisabeth C. Mertsching, Robert J. Benschop, David L. Boyle, Wei Wang, Gary S. Firestein
Published 2022-04-01

Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes

by Rizi Ai, Teresina Laragione, Deepa Hammaker, David L. Boyle, Andre Wildberg, Keisuke Maeshima, Emanuele Palescandolo, Vinod Krishna, David Pocalyko, John W. Whitaker, Yuchen Bai, Sunil Nagpal, Kurtis E. Bachman, Richard I. Ainsworth, Mengchi Wang, Bo Ding, Percio S. Gulko, Wei Wang, Gary S. Firestein
Published 2018-05-01

Multifaceted immune dysregulation characterizes individuals at-risk for rheumatoid arthritis

by Eddie A. James, V. Michael Holers, Radhika Iyer, E. Barton Prideaux, Navin L. Rao, Cliff Rims, Virginia S. Muir, Sylvia E. Posso, Michelle S. Bloom, Amin Zia, Serra E. Elliott, Julia Z. Adamska, Rizi Ai, R. Camille Brewer, Jennifer A. Seifert, LauraKay Moss, Saman Barzideh, M. Kristen Demoruelle, Christopher C. Striebich, Yuko Okamoto, Enkhtsogt Sainbayar, Alexandra A. Crook, Ryan A. Peterson, Lauren A. Vanderlinden, Wei Wang, David L. Boyle, William H. Robinson, Jane H. Buckner, Gary S. Firestein, Kevin D. Deane
Published 2023-11-01

Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium

by Garrett Dunlap, Aaron Wagner, Nida Meednu, Ruoqiao Wang, Fan Zhang, Jabea Cyril Ekabe, Anna Helena Jonsson, Kevin Wei, Saori Sakaue, Aparna Nathan, Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network, Vivian P. Bykerk, Laura T. Donlin, Susan M. Goodman, Gary S. Firestein, David L. Boyle, V. Michael Holers, Larry W. Moreland, Darren Tabechian, Costantino Pitzalis, Andrew Filer, Soumya Raychaudhuri, Michael B. Brenner, Juilee Thakar, Andrew McDavid, Deepak A. Rao, Jennifer H. Anolik
Published 2024-06-01

Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue

by Laura T. Donlin, Deepak A. Rao, Kevin Wei, Kamil Slowikowski, Mandy J. McGeachy, Jason D. Turner, Nida Meednu, Fumitaka Mizoguchi, Maria Gutierrez-Arcelus, David J. Lieb, Joshua Keegan, Kaylin Muskat, Joshua Hillman, Cristina Rozo, Edd Ricker, Thomas M. Eisenhaure, Shuqiang Li, Edward P. Browne, Adam Chicoine, Danielle Sutherby, Akiko Noma, Accelerating Medicines Partnership RA/SLE Network, Chad Nusbaum, Stephen Kelly, Alessandra B. Pernis, Lionel B. Ivashkiv, Susan M. Goodman, William H. Robinson, Paul J. Utz, James A. Lederer, Ellen M. Gravallese, Brendan F. Boyce, Nir Hacohen, Costantino Pitzalis, Peter K. Gregersen, Gary S. Firestein, Soumya Raychaudhuri, Larry W. Moreland, V. Michael Holers, Vivian P. Bykerk, Andrew Filer, David L. Boyle, Michael B. Brenner, Jennifer H. Anolik
Published 2018-07-01