The development and function of CD11c+ atypical B cells - insights from single cell analysis

by Xin Gao, Ian A. Cockburn
Published 2022-08-01

Innate immunity to malaria: The good, the bad and the unknown

by Kai Pohl, Kai Pohl, Ian A. Cockburn
Published 2022-08-01

B7-H1 blockade increases survival of dysfunctional CD8(+) T cells and confers protection against Leishmania donovani infections.

by Trupti Joshi, Susana Rodriguez, Vladimir Perovic, Ian A Cockburn, Simona Stäger
Published 2009-05-01

CD4+ T cells modulate expansion and survival but not functional properties of effector and memory CD8+ T cells induced by malaria sporozoites.

by Michael G Overstreet, Yun-Chi Chen, Ian A Cockburn, Sze-Wah Tse, Fidel Zavala
Published 2011-01-01

Clustering of Activated CD8 T Cells Around Malaria-Infected Hepatocytes Is Rapid and Is Driven by Antigen-Specific Cells

by Reka K. Kelemen, Reka K. Kelemen, Harshana Rajakaruna, Ian A. Cockburn, Vitaly V. Ganusov, Vitaly V. Ganusov
Published 2019-09-01

Dendritic cells and hepatocytes use distinct pathways to process protective antigen from plasmodium in vivo.

by Ian A Cockburn, Sze-Wah Tse, Andrea J Radtke, Prakash Srinivasan, Yun-Chi Chen, Photini Sinnis, Fidel Zavala
Published 2011-03-01

A New Method Based on the von Mises-Fisher Distribution Shows that a Minority of Liver-Localized CD8 T Cells Display Hard-To-Detect Attraction to Plasmodium-Infected Hepatocytes

by Viktor S. Zenkov, James H. O’Connor, James H. O’Connor, Ian A. Cockburn, Vitaly V. Ganusov, Vitaly V. Ganusov
Published 2022-01-01

Prolonged antigen presentation is required for optimal CD8+ T cell responses against malaria liver stage parasites.

by Ian A Cockburn, Yun-Chi Chen, Michael G Overstreet, Jason R Lees, Nico van Rooijen, Donna L Farber, Fidel Zavala
Published 2010-05-01

Lymph-node resident CD8α+ dendritic cells capture antigens from migratory malaria sporozoites and induce CD8+ T cell responses.

by Andrea J Radtke, Wolfgang Kastenmüller, Diego A Espinosa, Michael Y Gerner, Sze-Wah Tse, Photini Sinnis, Ronald N Germain, Fidel P Zavala, Ian A Cockburn
Published 2015-02-01

Splenic Dendritic Cells and Macrophages Drive B Cells to Adopt a Plasmablast Cell Fate

by Hayley A. McNamara, Hayley A. McNamara, Mireille H. Lahoud, Yeping Cai, Jessica Durrant-Whyte, James H. O’Connor, Irina Caminschi, Ian A. Cockburn
Published 2022-04-01

Avid binding by B cells to the Plasmodium circumsporozoite protein repeat suppresses responses to protective subdominant epitopes

by Deepyan Chatterjee, Fiona J. Lewis, Henry J. Sutton, Joe A. Kaczmarski, Xin Gao, Yeping Cai, Hayley A. McNamara, Colin J. Jackson, Ian A. Cockburn
Published 2021-04-01

Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites

by Esther Rajendran, Sanduni V. Hapuarachchi, Catherine M. Miller, Stephen J. Fairweather, Yeping Cai, Nicholas C. Smith, Ian A. Cockburn, Stefan Bröer, Kiaran Kirk, Giel G. van Dooren
Published 2017-02-01

T-dependent B cell responses to Plasmodium induce antibodies that form a high-avidity multivalent complex with the circumsporozoite protein.

by Camilla R Fisher, Henry J Sutton, Joe A Kaczmarski, Hayley A McNamara, Ben Clifton, Joshua Mitchell, Yeping Cai, Johanna N Dups, Nicholas J D'Arcy, Mandeep Singh, Aaron Chuah, Thomas S Peat, Colin J Jackson, Ian A Cockburn
Published 2017-07-01

Extrafollicular Plasmablasts Present in the Acute Phase of Infections Express High Levels of PD-L1 and Are Able to Limit T Cell Response

by Melisa Gorosito Serrán, Facundo Fiocca Vernengo, Laura Almada, Cristian G. Beccaria, Yamila Gazzoni, Pablo F. Canete, Jonathan A. Roco, Jimena Tosello Boari, Maria Cecilia Ramello, Ellen Wehrens, Yeping Cai, Elina I. Zuniga, Carolina L. Montes, Ian A. Cockburn, Eva V. Acosta Rodriguez, Carola G. Vinuesa, Carola G. Vinuesa, Adriana Gruppi
Published 2022-05-01

T follicular helper 17 (Tfh17) cells are superior for immunological memory maintenance

by Xin Gao, Kaiming Luo, Diya Wang, Yunbo Wei, Yin Yao, Jun Deng, Yang Yang, Qunxiong Zeng, Xiaoru Dong, Le Xiong, Dongcheng Gong, Lin Lin, Kai Pohl, Shaoling Liu, Yu Liu, Lu Liu, Thi HO Nguyen, Lilith F Allen, Katherine Kedzierska, Yanliang Jin, Mei-Rong Du, Wanping Chen, Liangjing Lu, Nan Shen, Zheng Liu, Ian A Cockburn, Wenjing Luo, Di Yu
Published 2023-01-01

Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans

by Henry J. Sutton, Racheal Aye, Azza H. Idris, Rachel Vistein, Eunice Nduati, Oscar Kai, Jedida Mwacharo, Xi Li, Xin Gao, T. Daniel Andrews, Marios Koutsakos, Thi H.O. Nguyen, Maxim Nekrasov, Peter Milburn, Auda Eltahla, Andrea A. Berry, Natasha KC, Sumana Chakravarty, B. Kim Lee Sim, Adam K. Wheatley, Stephen J. Kent, Stephen L. Hoffman, Kirsten E. Lyke, Philip Bejon, Fabio Luciani, Katherine Kedzierska, Robert A. Seder, Francis M. Ndungu, Ian A. Cockburn
Published 2021-02-01