The Basis and Promise of Programmable RNA Editing and Modification

by Nicholas Lo, Xin Xu, Fraser Soares, Housheng Hansen He, Housheng Hansen He
Published 2022-01-01

Genome-wide studies in prostate cancer poised liquid biopsy as a molecular discovery tool

by Nicholas Lo, Housheng Hansen He, Housheng Hansen He, Sujun Chen, Sujun Chen
Published 2023-08-01

Pioneer of prostate cancer: past, present and the future of FOXA1

by Mona Teng, Stanley Zhou, Changmeng Cai, Mathieu Lupien, Housheng Hansen He
Published 2020-09-01

DNA methylation modulated genetic variant effect on gene transcriptional regulation

by Yong Zeng, Rahi Jain, Magnus Lam, Musaddeque Ahmed, Haiyang Guo, Wenjie Xu, Yuan Zhong, Gong-Hong Wei, Wei Xu, Housheng Hansen He
Published 2023-12-01

Somatic driver mutation prevalence in 1844 prostate cancers identifies ZNRF3 loss as a predictor of metastatic relapse

by Michael Fraser, Julie Livingstone, Jeffrey L. Wrana, Antonio Finelli, Housheng Hansen He, Theodorus van der Kwast, Alexandre R. Zlotta, Robert G. Bristow, Paul C. Boutros
Published 2021-10-01

Refined RIP-seq protocol for epitranscriptome analysis with low input materials.

by Yong Zeng, Shiyan Wang, Shanshan Gao, Fraser Soares, Musadeqque Ahmed, Haiyang Guo, Miranda Wang, Junjie Tony Hua, Jiansheng Guan, Michael F Moran, Ming Sound Tsao, Housheng Hansen He
Published 2018-09-01

Androgen Receptor Tumor Suppressor Function Is Mediated by Recruitment of Retinoblastoma Protein

by Shuai Gao, Yanfei Gao, Housheng Hansen He, Dong Han, Wanting Han, Amy Avery, Jill A. Macoska, Xiaming Liu, Sen Chen, Fen Ma, Shaoyong Chen, Steven P. Balk, Changmeng Cai
Published 2016-10-01

High-dimensional genomic data bias correction and data integration using MANCIE

by Chongzhi Zang, Tao Wang, Ke Deng, Bo Li, Sheng’en Hu, Qian Qin, Tengfei Xiao, Shihua Zhang, Clifford A. Meyer, Housheng Hansen He, Myles Brown, Jun S. Liu, Yang Xie, X. Shirley Liu
Published 2016-04-01

Digital quantification of gene expression in sequential breast cancer biopsies reveals activation of an immune response.

by Rinath M Jeselsohn, Lillian Werner, Meredith M Regan, Aquila Fatima, Lauren Gilmore, Laura C Collins, Andrew H Beck, Shannon T Bailey, Housheng Hansen He, Gilles Buchwalter, Myles Brown, J Dirk Iglehart, Andrea Richardson, Steven E Come
Published 2013-01-01

Lysine-Specific Demethylase 1 Has Dual Functions as a Major Regulator of Androgen Receptor Transcriptional Activity

by Changmeng Cai, Housheng Hansen He, Shuai Gao, Sen Chen, Ziyang Yu, Yanfei Gao, Shaoyong Chen, Mei Wei Chen, Jesse Zhang, Musaddeque Ahmed, Yang Wang, Eric Metzger, Roland Schüle, X. Shirley Liu, Myles Brown, Steven P. Balk
Published 2014-12-01

N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis

by Daniel A. Kuppers, Sonali Arora, Yiting Lim, Andrea R. Lim, Lucas M. Carter, Philip D. Corrin, Christopher L. Plaisier, Ryan Basom, Jeffrey J. Delrow, Shiyan Wang, Housheng Hansen He, Beverly Torok-Storb, Andrew C. Hsieh, Patrick J. Paddison
Published 2019-10-01

Androgen receptor and MYC equilibration centralizes on developmental super-enhancer

by Haiyang Guo, Yiming Wu, Mannan Nouri, Sandor Spisak, Joshua W. Russo, Adam G. Sowalsky, Mark M. Pomerantz, Zhao Wei, Keegan Korthauer, Ji-Heui Seo, Liyang Wang, Seiji Arai, Matthew L. Freedman, Housheng Hansen He, Shaoyong Chen, Steven P. Balk
Published 2021-12-01

Oral pimonidazole unveils clinicopathologic and epigenetic features of hypoxic tumour aggressiveness in localized prostate cancer

by Xinpei Ci, Sujun Chen, Rui Zhu, Mojgan Zarif, Rahi Jain, Wangyuan Guo, Matthew Ramotar, Linsey Gong, Wenjie Xu, Olivia Singh, Sheila Mansouri, Gelareh Zadeh, Gong-Hong Wei, Wei Xu, Robert Bristow, Alejandro Berlin, Marianne Koritzinsky, Theodorus van der Kwast, Housheng Hansen He
Published 2024-06-01

Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation

by Zijun Chen, Zhengyang Li, Xiaojian Hu, Feiyan Xie, Siyun Kuang, Bowen Zhan, Wenqing Gao, Xiangjun Chen, Siqi Gao, Yang Li, Yongming Wang, Feng Qian, Chen Ding, Jianhua Gan, Chaoneng Ji, Xue‐Wei Xu, Zheng Zhou, Jinqing Huang, Housheng Hansen He, Jixi Li
Published 2020-07-01

MYC reshapes CTCF-mediated chromatin architecture in prostate cancer

by Zhao Wei, Song Wang, Yaning Xu, Wenzheng Wang, Fraser Soares, Musaddeque Ahmed, Ping Su, Tingting Wang, Elias Orouji, Xin Xu, Yong Zeng, Sujun Chen, Xiaoyu Liu, Tianwei Jia, Zhaojian Liu, Lutao Du, Yunshan Wang, Shaoyong Chen, Chuanxin Wang, Housheng Hansen He, Haiyang Guo
Published 2023-03-01

FOXA2 rewires AP-1 for transcriptional reprogramming and lineage plasticity in prostate cancer

by Zifeng Wang, Scott L. Townley, Songqi Zhang, Mingyu Liu, Muqing Li, Maryam Labaf, Susan Patalano, Kavita Venkataramani, Kellee R. Siegfried, Jill A. Macoska, Dong Han, Shuai Gao, Gail P. Risbridger, Renea A. Taylor, Mitchell G. Lawrence, Housheng Hansen He, Luke A. Selth, Changmeng Cai
Published 2024-06-01

SPOP mutation induces DNA methylation via stabilizing GLP/G9a

by Jianong Zhang, Kun Gao, Hongyan Xie, Dejie Wang, Pingzhao Zhang, Ting Wei, Yuqian Yan, Yunqian Pan, Wenbin Ye, Huifen Chen, Qing Shi, Yao Li, Shi-min Zhao, Xiaonan Hou, Saravut J. Weroha, Yuzhuo Wang, Jun Zhang, R. Jeffrey Karnes, Housheng Hansen He, Liguo Wang, Chenji Wang, Haojie Huang
Published 2021-09-01

K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression

by Zhenyue Hao, Yi Sheng, Gordon S. Duncan, Wanda Y. Li, Carmen Dominguez, Jennifer Sylvester, Yu-Wen Su, Gloria H.Y. Lin, Bryan E. Snow, Dirk Brenner, Annick You-Ten, Jillian Haight, Satoshi Inoue, Andrew Wakeham, Alisha Elford, Sara Hamilton, Yi Liang, Juan C. Zúñiga-Pflücker, Housheng Hansen He, Pamela S. Ohashi, Tak W. Mak
Published 2017-01-01

Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes

by Oliver A. Kent, Manipa Saha, Etienne Coyaud, Helen E. Burston, Napoleon Law, Keith Dadson, Sujun Chen, Estelle M. Laurent, Jonathan St-Germain, Ren X. Sun, Yoshinori Matsumoto, Justin Cowen, Aaryn Montgomery-Song, Kevin R. Brown, Charles Ishak, Jose La Rose, Daniel D. De Carvalho, Housheng Hansen He, Brian Raught, Filio Billia, Peter Kannu, Robert Rottapel
Published 2020-09-01

The cell-free DNA methylome captures distinctions between localized and metastatic prostate tumors

by Sujun Chen, Jessica Petricca, Wenbin Ye, Jiansheng Guan, Yong Zeng, Nicholas Cheng, Linsey Gong, Shu Yi Shen, Junjie T. Hua, Megan Crumbaker, Michael Fraser, Stanley Liu, Scott V. Bratman, Theodorus van der Kwast, Trevor Pugh, Anthony M. Joshua, Daniel D. De Carvalho, Kim N. Chi, Philip Awadalla, Guoli Ji, Felix Feng, Alexander W. Wyatt, Housheng Hansen He
Published 2022-10-01