Future perspectives in melanoma research. <it>Meeting report from the "Melanoma Research: a bridge Naples-USA. Naples, December 6^th-7 ^th2010"</it>

by Maio Michele, Schwartzentruber Douglas J, Sznol Mario, Lehmann Frederic F, Ullmann Claudio, Kirkwood John M, Fox Bernard A, Lee Peter P, Rivoltini Licia, Cochran Alistair, Wang Ena, Ferrone Soldano, Kashani-sabet Mohamed, Hendrix Mary, Halaban Ruth, Palmieri Giuseppe, Bertuzzi Stefano, De Maio Eleonora, Ascierto Paolo A, Flaherty Keith, Galon Jerome, Ribas Antoni, Yang James, Stroncek David F, Mozzillo Nicola, Marincola Franco M
Published 2011-03-01

FUTURE PERSPECTIVES IN MELANOMA RESEARCH. Meeting report from the “Melanoma Research: a bridge from Naples to the World. Napoli, December 5^th–6 ^th2011”

by Ascierto Paolo A, Grimaldi Antonio M, Curti Brendan, Faries Mark B, Ferrone Soldano, Flaherty Keith, Fox Bernard A, Gajewski Thomas F, Gershenwald Jeffrey E, Gogas Helen, Grossmann Kenneth, Hauschild Axel, Hodi F, Kefford Richard, Kirkwood John M, Leachmann Sancy, Maio Michele, Marais Richard, Palmieri Giuseppe, Morton Donald L, Ribas Antoni, Stroncek David F, Stewart Rodney, Wang Ena, Mozzillo Nicola, Marincola Franco M
Published 2012-07-01

Interim results of an ongoing Phase I, dose escalation study of MGA271 (Fc-optimized humanized anti-B7-H3 monoclonal antibody) in patients with refractory B7-H3-expressing neoplasm...

by Powderly, John, Cote, Gregory, Flaherty, Keith, Szmulewitz, Russell Z, Ribas, Antoni, Weber, Jeffrey, Loo, Deryk, Baughman, Jan, Chen, Francine, Moore, Paul, Bonvini, Ezio, Vasselli, James, Wigginton, Jon, Cohen, Roger, Burris, Howard, Chmielowski, Bartosz
Published 2015

Future Perspectives in melanoma research: Meeting report from the "Melanoma Research: a bridge Naples-USA. Naples, December 6th-7th 2010".

by Ascierto, Paolo A, De Maio, Eleonora, Bertuzzi, Stefano, Palmieri, Giuseppe, Halaban, Ruth, Hendrix, Mary, Kashani-sabet, Mohamed, Ferrone, Soldano, Wang, Ena, Cochran, Alistair, Rivoltini, Licia, Lee, Peter P, Fox, Bernard A, Kirkwood, John M, Ullmann, Claudio, Lehmann, Frederic F, Sznol, Mario, Schwartzentruber, Douglas J, Maio, Michele, Flaherty, Keith, Galon, Jerome, Ribas, Antoni, Yang, James, Stroncek, David F, Mozzillo, Nicola, Marincola, Franco M
Published 2011

Future Perspectives in melanoma research. Meeting report from the "Melanoma Research: a bridge from Naples to the World. Napoli, December 5th-6 th2011".

by Ascierto, Paolo A, Grimaldi, Antonio M, Curti, Brendan, Faries, Mark B, Ferrone, Soldano, Flaherty, Keith, Fox, Bernard A, Gajewski, Thomas F, Gershenwald, Jeffrey E, Gogas, Helen, Grossmann, Kenneth, Hauschild, Axel, Hodi, F, Kefford, Richard, Kirkwood, John M, Leachmann, Sancy, Maio, Michele, Marais, Richard, Palmieri, Giuseppe, Morton, Donald L, Ribas, Antoni, Stroncek, David F, Stewart, Rodney, Wang, Ena, Mozzillo, Nicola, Marincola, Franco M
Published 2012

Academic Cancer Center Phase I Program Development

by Frankel, Arthur E., Flaherty, Keith T., Weiner, George J., Chen, Robert, Azad, Nilofer S., Pishvaian, Michael J., Thompson, John A., Taylor, Matthew H., Mahadevan, Daruka, Lockhart, A. Craig, Vaishampayan, Ulka N., Berlin, Jordan D., Smith, David C., Sarantopoulos, John, Riese, Matthew, Saleh, Mansoor N., Ahn, Chul, Frenkel, Eugene P.
Published 2017

Plasma-derived extracellular vesicle analysis and deconvolution enable prediction and tracking of melanoma checkpoint blockade outcome

by Shi, Alvin, Kasumova, Gyulnara G, Michaud, William A, Cintolo-Gonzalez, Jessica, Díaz-Martínez, Marta, Ohmura, Jacqueline, Mehta, Arnav, Chien, Isabel, Frederick, Dennie T, Cohen, Sonia, Plana, Deborah, Johnson, Douglas, Flaherty, Keith T, Sullivan, Ryan J, Kellis, Manolis, Boland, Genevieve M
Published 2021

Loss of cohesin complex components STAG2 or STAG3 confers resistance to BRAF inhibition in melanoma

by Shen, Che-Hung, Kim, Sun Hye, Trousil, Sebastian, Frederick, Dennie T., Piris, Adriano, Yuan, Ping, Cai, Li, Gu, Lei, Li, Man, Lee, Jung Hyun, Mitra, Devarati, Fisher, David E., Sullivan, Ryan J., Flaherty, Keith T., Zheng, Bin
Published 2017

Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5-/- mice.

by Li, Yan, Tinoco, Roberto, Elmén, Lisa, Segota, Igor, Xian, Yibo, Fujita, Yu, Sahu, Avinash, Zarecki, Raphy, Marie, Kerrie, Feng, Yongmei, Khateb, Ali, Frederick, Dennie T, Ashkenazi, Shiri K, Kim, Hyungsoo, Perez, Eva Guijarro, Day, Chi-Ping, Segura Muñoz, Rafael S, Schmaltz, Robert, Yooseph, Shibu, Tam, Miguel A, Zhang, Tongwu, Avitan-Hersh, Emily, Tzur, Lihi, Roizman, Shoshana, Boyango, Ilanit, Bar-Sela, Gil, Orian, Amir, Kaufman, Randal J, Bosenberg, Marcus, Goding, Colin R, Baaten, Bas, Levesque, Mitchell P, Dummer, Reinhard, Brown, Kevin, Merlino, Glenn, Ruppin, Eytan, Flaherty, Keith, Ramer-Tait, Amanda, Long, Tao, Peterson, Scott N, Bradley, Linda M, Ronai, Ze'ev A
Published 2019

Impact of depth of response on survival in patients treated with cobimetinib ± vemurafenib: pooled analysis of BRIM-2, BRIM-3, BRIM-7 and coBRIM.

by Lewis, Karl D, Larkin, James, Ribas, Antoni, Flaherty, Keith T, McArthur, Grant A, Ascierto, Paolo A, Dréno, Brigitte, Yan, Yibing, Wongchenko, Matthew, McKenna, Edward, Zhu, Qian, Mun, Yong, Hauschild, Axel
Published 2019

Plasma-derived extracellular vesicle analysis and deconvolution enable prediction and tracking of melanoma checkpoint blockade outcome

by Shi, Alvin, Kasumova, Gyulnara G, Michaud, William A, Cintolo-Gonzalez, Jessica, Díaz-Martínez, Marta, Ohmura, Jacqueline, Mehta, Arnav, Chien, Isabel, Frederick, Dennie T, Cohen, Sonia, Plana, Deborah, Johnson, Douglas, Flaherty, Keith T, Sullivan, Ryan J, Kellis, Manolis, Boland, Genevieve M
Published 2022

PDGFRα up-regulation mediated by sonic hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation

by Sabbatino, Francesco, Wang, Yangyang, Wang, Xinhui, Flaherty, Keith T., Yu, Ling, Pepin, David, Scognamiglio, Giosue', Pepe, Stefano, Kirkwood, John M., Cooper, Zachary A., Frederick, Dennie T., Wargo, Jennifer A., Ferrone, Soldano, Ferrone, Cristina R.
Published 2014

A melanocyte lineage program confers resistance to MAP kinase pathway inhibition

by Johannessen, Cory M., Johnson, Laura A., Piccioni, Federica, Townes, Aisha, Frederick, Dennie T., Donahue, Melanie K., Narayan, Rajiv, Flaherty, Keith T., Wargo, Jennifer A., Root, David E., Garraway, Levi A.
Published 2014

Overexpression of Mcl-1 confers resistance to BRAFV600E inhibitors alone and in combination with MEK1/2 inhibitors in melanoma

by Fofaria, Neel M., Frederick, Dennie T., Sullivan, Ryan J., Flaherty, Keith T., Srivastava, Sanjay K.
Published 2016

Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation

by Kim, Hyungsoo, Frederick, Dennie T., Levesque, Mitchell P., Cooper, Zachary A., Feng, Yongmei, Krepler, Clemens, Brill, Laurence, Samuels, Yardena, Hayward, Nicholas K., Perlina, Ally, Piris, Adriano, Zhang, Tongwu, Halaban, Ruth, Herlyn, Meenhard M., Brown, Kevin M., Wargo, Jennifer A., Dummer, Reinhard, Flaherty, Keith T., Ronai, Ze’ev A.
Published 2016

Mechanisms of resistance to immune checkpoint inhibitors

by Jenkins, Russell W, Barbie, David A, Flaherty, Keith T
Published 2018

Resistance to checkpoint blockade therapy through inactivation of antigen presentation

by Sade-Feldman, Moshe, Jiao, Yunxin J., Chen, Jonathan H., Rooney, Michael S., Barzily-Rokni, Michal, Eliane, Jean-Pierre, Bjorgaard, Stacey L., Hammond, Marc R., Vitzthum, Hans, Blackmon, Shauna M., Frederick, Dennie T., Hazar-Rethinam, Mehlika, Nadres, Brandon A., Van Seventer, Emily E., Shukla, Sachet A., Yizhak, Keren, Ray, John P., Rosebrock, Daniel, Livitz, Dimitri, Adalsteinsson, Viktor, Getz, Gad, Duncan, Lyn M., Li, Bo, Corcoran, Ryan B., Lawrence, Donald P., Stemmer-Rachamimov, Anat, Boland, Genevieve M., Landau, Dan A., Flaherty, Keith T., Sullivan, Ryan J., Hacohen, Nir
Published 2017

Tumor Neoantigens and a Novel Hapten Vaccine Promote Immune Targeting of Wild-Type Tumor Lineage Antigens and Improve Response to Immune Checkpoint Blockade

by Su, Mack
Published 2019

BRAF inhibition is associated with increased clonality in tumor-infiltrating lymphocytes

by Cooper, Zachary A, Frederick, Dennie T, Juneja, Vikram R, Sullivan, Ryan J, Lawrence, Donald P, Piris, Adriano, Sharpe, Arlene H, Fisher, David E, Flaherty, Keith T, Wargo, Jennifer A
Published 2014

Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine

by Geller, Leore T., Barzily-Rokni, Michal, Danino, Tal, Jonas, Oliver H., Shental, Noam, Nejman, Deborah, Gavert, Nancy, Zwang, Yaara, Cooper, Zachary A., Shee, Kevin, Thaiss, Christoph A., Reuben, Alexandre, Livny, Jonathan, Avraham, Roi, Frederick, Dennie T., Ligorio, Matteo, Chatman, Kelly, Johnston, Stephen E., Mosher, Carrie M., Brandis, Alexander, Fuks, Garold, Gurbatri, Candice, Gopalakrishnan, Vancheswaran, Kim, Michael, Hurd, Mark W., Katz, Matthew, Fleming, Jason, Maitra, Anirban, Smith, David A., Skalak, Matthew T., Bu, Jeffrey, Michaud, Monia, Trauger, Sunia A., Barshack, Iris, Golan, Talia, Sandbank, Judith, Flaherty, Keith T., Mandinova, Anna, Garrett, Wendy S., Thayer, Sarah P., Ferrone, Cristina R., Huttenhower, Curtis, Bhatia, Sangeeta N., Gevers, Dirk, Wargo, Jennifer A., Golub, Todd R., Straussman, Ravid
Published 2020