Comparison of RNA extraction methods for the detection of SARS-CoV-2 by RT-PCR

by Eichhoff, Ossia M., Bellini, Elisa, Lienhard, Reto, Stark, Wendelin J., Bechtold, Philippe, Grass, Robert N., Bosshard, Philipp P., Levesque, Mitchell P.
Published 2020

The multifaceted roles of Nrf2 in immunity, wound healing, and epidermal barrier function

by Muzumdar, Sukalp
Published 2019

Collection and preprocessing of fine needle aspirate patient samples for single cell profiling and data analysis

by Tastanova, Aizhan, Ramelyte, Egle, Balázs, Zsolt, Menzel, Ulrike, Beisel, Christian, Krauthammer, Michael, Dummer, Reinhard, Levesque, Mitchell P.
Published 2021

Live slow-frozen human tumor tissues viable for 2D, 3D, ex vivo cultures and single-cell RNAseq

by Restivo, Gaetana, Tastanova, Aizhan, Balázs, Zsolt, Panebianco, Federica, Diepenbruck, Maren, Ercan, Caner, Preca, Bodgan-T., Hafner, Jürg, Weber, Walter P., Kurzeder, Christian, Vetter, Marcus, Soysal, Simone Münst, Beisel, Christian, Bentires-Alj, Mohamed, Piscuoglio, Salvatore, Krauthammer, Michael, Levesque, Mitchell P.
Published 2022

NGS-pipe: A flexible, easily extendable and highly configurable framework for NGS analysis

by Singer, Jochen, Ruscheweyh, Hans-Joachim; id_orcid0000-0001-7473-6086, Hofmann, Ariane L., Thurnherr, Thomas, Singer, Franziska, Toussaint, Nora C., Ng, Charlotte K.Y., Piscuoglio, Salvatore, Beisel, Christian, Christofori, Gerhard, Dummer, Reinhard, Hall, Michael N., Krek, Wilhelm, Levesque, Mitchell P., Manz, Markus G., Moch, Holger, Papassotiropoulos, Andreas, Stekhoven, Daniel J., Wild, Peter, Wüst, Thomas, Rinn, Bernd, Beerenwinkel, Niko; id_orcid0000-0002-0573-6119
Published 2018

Unexpected contribution of lymphatic vessels to promotion of distant metastatic tumor spread

by Ma, Qiaoli, Dieterich, Lothar C., Ikenberg, Kristian, Bachmann, Samia B., Mangana, Johanna, Proulx, Steven T., Amann, Valerie C., Levesque, Mitchell P., Dummer, Reinhard, Baluk, Peter, McDonald, Donald M., Detmar, Michael
Published 2018

NRASQ61K melanoma tumor formation is reduced by p38-MAPK14 activation in zebrafish models and NRAS-mutated human melanoma cells.

by Banik, Ishani, Cheng, Phil F, Dooley, Christopher M, Travnickova, Jana, Merteroglu, Munise, Dummer, Reinhard, Patton, Elizabeth E, Busch-Nentwich, Elisabeth M, Levesque, Mitchell P
Published 2020

A DNA replication-independent function of pre-replication complex genes during cell invasion in C. elegans

by Lattmann, Evelyn, Deng, Ting, Walser, Michael, Widmer, Patrizia, Rexha-Lambert, Charlotte, Prasad, Vibhu, Eichhoff, Ossia, Daube, Michael, Dummer, Reinhard, Levesque, Mitchell P., Hajnal, Alex
Published 2022

Bioinformatics for Precision Oncology

by Singer, Jochen, Irmisch, Anja, Ruscheweyh, Hans-Joachim; id_orcid0000-0001-7473-6086, Singer, Franziska, Toussaint, Nora C., Levesque, Mitchell P., Stekhoven, Daniel J., Beerenwinkel, Niko; id_orcid0000-0002-0573-6119
Published 2019

Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation

by Kim, Hyungsoo, Frederick, Dennie T., Levesque, Mitchell P., Cooper, Zachary A., Feng, Yongmei, Krepler, Clemens, Brill, Laurence, Samuels, Yardena, Hayward, Nicholas K., Perlina, Ally, Piris, Adriano, Zhang, Tongwu, Halaban, Ruth, Herlyn, Meenhard M., Brown, Kevin M., Wargo, Jennifer A., Dummer, Reinhard, Flaherty, Keith T., Ronai, Ze’ev A.
Published 2016

Novel Blood Vascular Endothelial Subtype-Specific Markers in Human Skin Unearthed by Single-Cell Transcriptomic Profiling

by He, Yuliang, Tacconi, Carlotta, Dieterich, Lothar C., Kim, Jihye, Restivo, Gaetana, Gousopoulos, Epameinondas, Lindenblatt, Nicole, Levesque, Mitchell P., Claassen, Manfred, Detmar, Michael
Published 2022

Quantifying SARS-CoV-2 spread in Switzerland based on genomic sequencing data

by Nadeau, Sarah Ann; id_orcid0000-0003-1008-8918, Beckmann, Christiane, Topolsky, Ivan; id_orcid0000-0002-7561-0810, Vaughan, Timothy, Hodcroft, Emma, Schär, Tobias, Nissen, Ina, Santacroce, Natascha, Burcklen, Elodie, Ferreira, Pedro, Jablonski, Kim Philipp; id_orcid0000-0002-4166-4343, Posada Cespedes, Susana; id_orcid0000-0002-7459-8186, Capece, Vincenzo, Seidel, Sophie, Santamaria de Souza, Noemi; id_orcid0000-0001-7134-7480, Martinez-Gomez, Julia M., Cheng, Phil, Bosshard, Philipp P., Levesque, Mitchell P., Kufner, Verena, Schmutz, Stefan, Zaheri, Maryam, Huber, Michael, Trkola, Alexandra, Cordey, Samuel, Laubscher, Florian, Gonçalves, Ana Rita, Leuzinger, Karoline, Stange, Madlen, Mari, Alfredo, Roloff, Tim, Seth-Smith, Helena, Hirsch, Hans H., Egli, Adrian, Redondo, Maurice, Kobel, Oliver, Noppen, Christoph, Beerenwinkel, Niko; id_orcid0000-0002-0573-6119, Neher, Richard A., Beisel, Christian, Stadler, Tanja; id_orcid0000-0001-6431-535X
Published 2020

Temporal activation of WNT/beta-catenin signaling is sufficient to inhibit SOX10 expression and block melanoma growth

by Uka, Rexhep, Britschgi, Christian, Krättli, Anja, Matter, Claudia, Mihic, Daniela, Okoniewski, Michal J., Gualandi, Marco, Stupp, Roger, Cinelli, Paolo, Dummer, Reinhard, Levesque, Mitchell P., Shakhova, Olga
Published 2020

SwissMTB: Establishing comprehensive molecular cancer diagnostics in Swiss clinics

by Singer, Franziska, Irmisch, Anja, Toussaint, Nora C., Grob, Linda, Singer, Jochen, Thurnherr, Thomas, Beerenwinkel, Niko, Levesque, Mitchell P., Dummer, Reinhard, Quagliata, Luca, Rothschild, Sacha I., Wicki, Andreas, Beisel, Christian, Stekhoven, Daniel J.
Published 2018

miR-181a decelerates proliferation in cutaneous squamous cell carcinoma by targeting the proto-oncogene KRAS

by Neu, Johannes, Dziunycz, Piotr J., Dzung, Andreas, Lefort, Karine, Falke, Martin, Denzler, Rémy C., Freiberger, Sandra N., Iotzova-Weiss, Guergana, Kuzmanov, Aleksandar, Levesque, Mitchell P., Dotto, Gian-Paolo, Hofbauer, Günther F.L.
Published 2017

A fatty acid oxidation-dependent metabolic shift regulates the adaptation of BRAF-mutated melanoma to MAPK inhibitors

by Aloia, Andrea, Müllhaupt, Daniela, Chabbert, Christophe D., Eberhart, Tanja, Flückiger-Mangual, Stefanie, Vukolic, Ana, Eichhoff, Ossia, Irmisch, Anja, Alexander, Leila T., Scibona, Ernesto; id_orcid0000-0002-2012-5674, Frederick, Dennie T., Miao, Benchun, Tian, Tian, Cheng, Chaoran, Kwong, Lawrence N., Sullivan, Ryan J., Boland, Genevieve M., Herlyn, Meenhard, Flaherty, Keith T., Zamboni, Nicola; id_orcid0000-0003-1271-1021, Dummer, Reinhard, Zhang, Gao, Levesque, Mitchell P., Krek, Wilhelm, Kovacs, Werner J.
Published 2019