Core Steps of Membrane-Bound Peptidoglycan Biosynthesis: Recent Advances, Insight and Opportunities

by Alvin C. K. Teo, David I. Roper
Published 2015-11-01

The pH dependence of polymerization and bundling by the essential bacterial cytoskeletal protein FtsZ.

by Raúl Pacheco-Gómez, David I Roper, Timothy R Dafforn, Alison Rodger
Published 2011-01-01

The Pneumococcal Divisome: Dynamic Control of Streptococcus pneumoniae Cell Division

by Nicholas S. Briggs, Kevin E. Bruce, Souvik Naskar, Malcolm E. Winkler, David I. Roper
Published 2021-10-01

Investigating the effect of bacteriophages on bacterial FtsZ localisation

by Gurneet K. Dhanoa, Inbar Kushnir, Udi Qimron, David I. Roper, Antonia P. Sagona
Published 2022-07-01

CO2 directly modulates connexin 26 by formation of carbamate bridges between subunits

by Louise Meigh, Sophie A Greenhalgh, Thomas L Rodgers, Martin J Cann, David I Roper, Nicholas Dale
Published 2013-11-01

The role of the jaw subdomain of peptidoglycan glycosyltransferases for lipid II polymerization

by Avinash S. Punekar, Firdaus Samsudin, Adrian J. Lloyd, Christopher G. Dowson, David J. Scott, Syma Khalid, David I. Roper
Published 2018-06-01

A Dynamic Network of Proteins Facilitate Cell Envelope Biogenesis in Gram-Negative Bacteria

by Chris L. B. Graham, Hector Newman, Francesca N. Gillett, Katie Smart, Nicholas Briggs, Manuel Banzhaf, David I. Roper
Published 2021-11-01

Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing.

by Elena S Lysenko, Thomas B Clarke, Mikhail Shchepetov, Adam J Ratner, David I Roper, Christopher G Dowson, Jeffrey N Weiser
Published 2007-08-01

In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA).

by David Sychantha, Carys S Jones, Dustin J Little, Patrick J Moynihan, Howard Robinson, Nicola F Galley, David I Roper, Christopher G Dowson, P Lynne Howell, Anthony J Clarke
Published 2017-10-01

Bacterial Lipid II Analogs: Novel In Vitro Substrates for Mammalian Oligosaccharyl Diphosphodolichol Diphosphatase (DLODP) Activities

by Ahmad Massarweh, Michael Bosco, Isabelle Chantret, Thibaut Léger, Layla Jamal, David I. Roper, Christopher G. Dowson, Patricia Busca, Ahmed Bouhss, Christine Gravier-Pelletier, Stuart E. H. Moore
Published 2019-06-01

Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine

by Sarah Batson, Cesira de Chiara, Vita Majce, Adrian J. Lloyd, Stanislav Gobec, Dean Rea, Vilmos Fülöp, Christopher W. Thoroughgood, Katie J. Simmons, Christopher G. Dowson, Colin W. G. Fishwick, Luiz Pedro S. de Carvalho, David I. Roper
Published 2017-12-01

Structural basis of peptidoglycan synthesis by E. coli RodA-PBP2 complex

by Rie Nygaard, Chris L. B. Graham, Meagan Belcher Dufrisne, Jonathan D. Colburn, Joseph Pepe, Molly A. Hydorn, Silvia Corradi, Chelsea M. Brown, Khuram U. Ashraf, Owen N. Vickery, Nicholas S. Briggs, John J. Deering, Brian Kloss, Bruno Botta, Oliver B. Clarke, Linda Columbus, Jonathan Dworkin, Phillip J. Stansfeld, David I. Roper, Filippo Mancia
Published 2023-08-01

Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis

by Anh T. Tran, Emma E. Watson, Venugopal Pujari, Trent Conroy, Luke J. Dowman, Andrew M. Giltrap, Angel Pang, Weng Ruh Wong, Roger G. Linington, Sebabrata Mahapatra, Jessica Saunders, Susan A. Charman, Nicholas P. West, Timothy D. H. Bugg, Julie Tod, Christopher G. Dowson, David I. Roper, Dean C. Crick, Warwick J. Britton, Richard J. Payne
Published 2017-03-01

Structure of dual BON-domain protein DolP identifies phospholipid binding as a new mechanism for protein localisation

by Jack Alfred Bryant, Faye C Morris, Timothy J Knowles, Riyaz Maderbocus, Eva Heinz, Gabriela Boelter, Dema Alodaini, Adam Colyer, Peter J Wotherspoon, Kara A Staunton, Mark Jeeves, Douglas F Browning, Yanina R Sevastsyanovich, Timothy J Wells, Amanda E Rossiter, Vassiliy N Bavro, Pooja Sridhar, Douglas G Ward, Zhi-Soon Chong, Emily CA Goodall, Christopher Icke, Alvin CK Teo, Shu-Sin Chng, David I Roper, Trevor Lithgow, Adam F Cunningham, Manuel Banzhaf, Michael Overduin, Ian R Henderson
Published 2020-12-01