Synthesis and Characterization of Partially and Fully Saturated Menaquinone Derivatives

by Jordan T. Koehn, Dean C. Crick, Debbie C. Crans
Published 2018-11-01

Decavanadate Inhibits Mycobacterial Growth More Potently Than Other Oxovanadates

by Nuttaporn Samart, Nuttaporn Samart, Zeyad Arhouma, Zeyad Arhouma, Santosh Kumar, Heide A. Murakami, Dean C. Crick, Dean C. Crick, Debbie C. Crans, Debbie C. Crans
Published 2018-11-01

Pyrazinoic acid, the active form of the anti-tuberculosis drug pyrazinamide, and aromatic carboxylic acid analogs are protonophores

by Fabio L. Fontes, Fabio L. Fontes, Steven A. Rooker, Jamie K. Lynn-Barbe, Michael A. Lyons, Debbie C. Crans, Debbie C. Crans, Dean C. Crick, Dean C. Crick
Published 2024-02-01

Electron Transport Lipids Fold Within Membrane-Like Interfaces

by Margaret M. Braasch-Turi, Jordan T. Koehn, Kateryna Kostenkova, Cameron Van Cleave, Jacob W. Ives, Heide A. Murakami, Dean C. Crick, Dean C. Crick, Debbie C. Crans, Debbie C. Crans
Published 2022-03-01

Lipidomic analyses of Mycobacterium tuberculosis based on accurate mass measurements and the novel “Mtb LipidDB”[S]

by Mark J. Sartain, Donald L. Dick, Christopher D. Rithner, Dean C. Crick, John T. Belisle
Published 2011-05-01

Stearoly-CoA desaturase 1 differentiates early and advanced dengue virus infections and determines virus particle infectivity.

by Rebekah C Gullberg, J Jordan Steel, Venugopal Pujari, Joel Rovnak, Dean C Crick, Rushika Perera
Published 2018-08-01

Characterization of MenA (isoprenyl diphosphate:1,4-dihydroxy-2-naphthoate isoprenyltransferase) from Mycobacterium tuberculosis.

by Rakesh K Dhiman, Venugopal Pujari, James M Kincaid, Melanie A Ikeh, Tanya Parish, Dean C Crick
Published 2019-01-01

Exploring Growth of <i>Mycobacterium smegmatis</i> Treated with Anticarcinogenic Vanadium Compounds

by Zeyad Arhouma, Heide A. Murakami, Jordan T. Koehn, Xiaorong Li, Deborah A. Roess, Dean C. Crick, Debbie C. Crans
Published 2022-04-01

Identification of a novel class of ω,E,E-farnesyl diphosphate synthase from Mycobacterium tuberculosis

by Rakesh K. Dhiman, Mark C. Schulbach, Sebabrata Mahapatra, Alain R. Baulard, Varalakshmi Vissa, Patrick J. Brennan, Dean C. Crick
Published 2004-06-01

Proline Dehydrogenase and Pyrroline 5 Carboxylate Dehydrogenase from <i>Mycobacterium tuberculosis:</i> Evidence for Substrate Channeling

by Santosh Kumar, Steven Sega, Jamie K. Lynn-Barbe, Dannika L. Harris, Jordan T. Koehn, Debbie C. Crans, Dean C. Crick
Published 2023-09-01

Partial Saturation of Menaquinone in Mycobacterium tuberculosis: Function and Essentiality of a Novel Reductase, MenJ

by Ashutosh Upadhyay, Fabio L. Fontes, Mercedes Gonzalez-Juarrero, Michael R. McNeil, Debbie C. Crans, Mary Jackson, Dean C. Crick
Published 2015-08-01

Multiple M. tuberculosis phenotypes in mouse and guinea pig lung tissue revealed by a dual-staining approach.

by Gavin J Ryan, Donald R Hoff, Emily R Driver, Martin I Voskuil, Mercedes Gonzalez-Juarrero, Randall J Basaraba, Dean C Crick, John S Spencer, Anne J Lenaerts
Published 2010-06-01

Interactions of Truncated Menaquinones in Lipid Monolayers and Bilayers

by Cameron Van Cleave, Jordan T. Koehn, Caroline Simões Pereira, Allison A. Haase, Benjamin J. Peters, Seth W. Croslow, Kyle G. McLaughlin, Katarina R. Werst, Audra L. Goach, Dean C. Crick, Guilherme Menegon Arantes, Debbie C. Crans
Published 2021-09-01

Genome-scale analysis of the genes that contribute to Burkholderia pseudomallei biofilm formation identifies a crucial exopolysaccharide biosynthesis gene cluster.

by Grace I Borlee, Brooke A Plumley, Kevin H Martin, Nawarat Somprasong, Mihnea R Mangalea, M Nurul Islam, Mary N Burtnick, Paul J Brett, Ivo Steinmetz, David P AuCoin, John T Belisle, Dean C Crick, Herbert P Schweizer, Bradley R Borlee
Published 2017-06-01

Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis

by Anh T. Tran, Emma E. Watson, Venugopal Pujari, Trent Conroy, Luke J. Dowman, Andrew M. Giltrap, Angel Pang, Weng Ruh Wong, Roger G. Linington, Sebabrata Mahapatra, Jessica Saunders, Susan A. Charman, Nicholas P. West, Timothy D. H. Bugg, Julie Tod, Christopher G. Dowson, David I. Roper, Dean C. Crick, Warwick J. Britton, Richard J. Payne
Published 2017-03-01