Batf3-dependent orchestration of the robust Th1 responses and fungal control during cryptococcal infection, the role of cDC1

by Jintao Xu, Rylan Hissong, Rachel Bareis, Arianna Creech, Kristie D. Goughenour, Christine M. Freeman, Michal A. Olszewski
Published 2024-03-01

Bacterial Topography of the Healthy Human Lower Respiratory Tract

by Robert P. Dickson, John R. Erb-Downward, Christine M. Freeman, Lisa McCloskey, Nicole R. Falkowski, Gary B. Huffnagle, Jeffrey L. Curtis
Published 2017-03-01

Analysis of the Upper Respiratory Tract Microbiotas as the Source of the Lung and Gastric Microbiotas in Healthy Individuals

by Christine M. Bassis, John R. Erb-Downward, Robert P. Dickson, Christine M. Freeman, Thomas M. Schmidt, Vincent B. Young, James M. Beck, Jeffrey L. Curtis, Gary B. Huffnagle
Published 2015-05-01

Changes in the lung microbiome following lung transplantation include the emergence of two distinct Pseudomonas species with distinct clinical associations.

by Robert P Dickson, John R Erb-Downward, Christine M Freeman, Natalie Walker, Brittan S Scales, James M Beck, Fernando J Martinez, Jeffrey L Curtis, Vibha N Lama, Gary B Huffnagle
Published 2014-01-01

Human CD56+ cytotoxic lung lymphocytes kill autologous lung cells in chronic obstructive pulmonary disease.

by Christine M Freeman, Valerie R Stolberg, Sean Crudgington, Fernando J Martinez, MeiLan K Han, Stephen W Chensue, Douglas A Arenberg, Catherine A Meldrum, Lisa McCloskey, Jeffrey L Curtis
Published 2014-01-01

Analysis of the lung microbiome in the "healthy" smoker and in COPD.

by John R Erb-Downward, Deborah L Thompson, Meilan K Han, Christine M Freeman, Lisa McCloskey, Lindsay A Schmidt, Vincent B Young, Galen B Toews, Jeffrey L Curtis, Baskaran Sundaram, Fernando J Martinez, Gary B Huffnagle
Published 2011-02-01

Basal gene expression by lung CD4+ T cells in chronic obstructive pulmonary disease identifies independent molecular correlates of airflow obstruction and emphysema extent.

by Christine M Freeman, Alexandra L McCubbrey, Sean Crudgington, Joshua Nelson, Fernando J Martinez, MeiLan K Han, George R Washko, Stephen W Chensue, Douglas A Arenberg, Catherine A Meldrum, Lisa McCloskey, Jeffrey L Curtis
Published 2014-01-01

Critical Relevance of Stochastic Effects on Low-Bacterial-Biomass 16S rRNA Gene Analysis

by John R. Erb-Downward, Nicole R. Falkowski, Jennifer C. D’Souza, Lisa M. McCloskey, Roderick A. McDonald, Christopher A. Brown, Kerby Shedden, Robert P. Dickson, Christine M. Freeman, Kathleen A. Stringer, Betsy Foxman, Gary B. Huffnagle, Jeffrey L. Curtis, Sara D. Adar
Published 2020-06-01

The matrikine acetyl-proline-glycine-proline and clinical features of COPD: findings from SPIROMICS

by J. Michael Wells, Dongqi Xing, Liliana Viera, Robert M. Burkes, Yixin Wu, Surya P. Bhatt, Mark T. Dransfield, David J. Couper, Wanda O’Neal, Eric A. Hoffman, Amit Gaggar, Igor Barjaktarevic, Jeffrey L. Curtis, Wassim W. Labaki, Mei Lan K. Han, Christine M. Freeman, Nirupama Putcha, Thomas Schlange, J. Edwin Blalock, for the SPIROMICS Investigators
Published 2019-11-01

Black carbon content in airway macrophages is associated with increased severe exacerbations and worse COPD morbidity in SPIROMICS

by Vickram Tejwani, Han Woo, Chen Liu, Anna K. Tillery, Amanda J. Gassett, Richard E. Kanner, Eric A. Hoffman, Fernando J. Martinez, Prescott G. Woodruff, R. Graham Barr, Ashraf Fawzy, Kirsten Koehler, Jeffrey L. Curtis, Christine M. Freeman, Christopher B. Cooper, Alejandro P. Comellas, Cheryl Pirozzi, Robert Paine, Donald Tashkin, Jerry A. Krishnan, Coralynn Sack, Nirupama Putcha, Laura M. Paulin, Marina Zusman, Joel D. Kaufman, Neil E. Alexis, Nadia N. Hansel
Published 2022-11-01

A blood and bronchoalveolar lavage protein signature of rapid FEV1 decline in smoking-associated COPD

by Katarina M. DiLillo, Katy C. Norman, Christine M. Freeman, Stephanie A. Christenson, Neil E. Alexis, Wayne H. Anderson, Igor Z. Barjaktarevic, R. Graham Barr, Alejandro P. Comellas, Eugene R. Bleecker, Richard C. Boucher, David J. Couper, Gerard J. Criner, Claire M. Doerschuk, J. Michael Wells, MeiLan K. Han, Eric A. Hoffman, Nadia N. Hansel, Annette T. Hastie, Robert J. Kaner, Jerry A. Krishnan, Wassim W. Labaki, Fernando J. Martinez, Deborah A. Meyers, Wanda K. O’Neal, Victor E. Ortega, Robert Paine, Stephen P. Peters, Prescott G. Woodruff, Christopher B. Cooper, Russell P. Bowler, Jeffrey L. Curtis, Kelly B. Arnold, SPIROMICS investigators
Published 2023-05-01

Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD.

by Wei Sun, Katerina Kechris, Sean Jacobson, M Bradley Drummond, Gregory A Hawkins, Jenny Yang, Ting-Huei Chen, Pedro Miguel Quibrera, Wayne Anderson, R Graham Barr, Patricia V Basta, Eugene R Bleecker, Terri Beaty, Richard Casaburi, Peter Castaldi, Michael H Cho, Alejandro Comellas, James D Crapo, Gerard Criner, Dawn Demeo, Stephanie A Christenson, David J Couper, Jeffrey L Curtis, Claire M Doerschuk, Christine M Freeman, Natalia A Gouskova, MeiLan K Han, Nicola A Hanania, Nadia N Hansel, Craig P Hersh, Eric A Hoffman, Robert J Kaner, Richard E Kanner, Eric C Kleerup, Sharon Lutz, Fernando J Martinez, Deborah A Meyers, Stephen P Peters, Elizabeth A Regan, Stephen I Rennard, Mary Beth Scholand, Edwin K Silverman, Prescott G Woodruff, Wanda K O'Neal, Russell P Bowler, SPIROMICS Research Group, COPDGene Investigators
Published 2016-08-01