Unmet need in severe, uncontrolled asthma: can anti-TSLP therapy with tezepelumab provide a valuable new treatment option?

by Andrew Menzies-Gow, Michael E. Wechsler, Chris E. Brightling
Published 2020-10-01

Human Lung Mast Cells: Therapeutic Implications in Asthma

by Remo Poto, Gjada Criscuolo, Gianni Marone, Chris E. Brightling, Gilda Varricchi
Published 2022-11-01

CASCADE: a phase 2, randomized, double-blind, placebo-controlled, parallel-group trial to evaluate the effect of tezepelumab on airway inflammation in patients with uncontrolled as...

by Claire Emson, Sarah Diver, Latifa Chachi, Ayman Megally, Cherrie Small, John Downie, Jane R. Parnes, Karin Bowen, Gene Colice, Chris E. Brightling
Published 2020-10-01

Severe exacerbations in moderate-to-severe asthmatics are associated with increased pro-inflammatory and type 1 mediators in sputum and serum

by Michael A. Ghebre, Pee Hwee Pang, Dhananjay Desai, Beverley Hargadon, Chris Newby, Joanne Woods, Laura Rapley, Suzanne E. Cohen, Athula Herath, Erol A. Gaillard, Richard D. May, Chris E. Brightling
Published 2019-08-01

Understanding the burden of interstitial lung disease post-COVID-19: the UK Interstitial Lung Disease-Long COVID Study (UKILD-Long COVID)

by R Gisli Jenkins, A John Simpson, Nicholas D Weatherley, Guilhem Collier, Jim M Wild, David R Thickett, Shaney L Barratt, Nazia Chaudhuri, Ling-Pei Ho, Lisa G Spencer, John F Blaikley, Fasihul Khan, Iain Stewart, John Kenneth Baillie, Rod Lawson, Simon R Johnson, Paul Beirne, Mark Spears, Laura Fabbri, Joseph Jacob, Mark G Jones, Bibek Gooptu, Rachel C Chambers, Philip L Molyneaux, Peter M George, Michael A Gibbons, Emma K Denneny, Joanna C Porter, Manuela Platé, Stephen M Bianchi, Chris E Brightling, Richard James Allen, Annemarie Docherty, Jane A Mitchell, Ian P Hall, Jonathan Brooke, Louise V Wain, Malcolm Semple, Raminder Aul, Neil A Hanley, Krisnah Poinasamy, Pilar Rivera-Ortega, DJF Smith, Stefan C Stanel, A A Roger Thompson, Simon LF Walsh, Mark Everard Weeks, Dan G Wootton, Karen Piper Hanley
Published 2021-11-01