The Induction of Alpha-1 Antitrypsin by Vitamin D in Human T Cells Is TGF-β Dependent: A Proposed Anti-inflammatory Role in Airway Disease

by Yin-Huai Chen, Charlotte E. Cheadle, Charlotte E. Cheadle, Louise V. Rice, Louise V. Rice, Paul E. Pfeffer, Paul E. Pfeffer, Sarah Dimeloe, Atul Gupta, Atul Gupta, Andrew Bush, Bibek Gooptu, Bibek Gooptu, Bibek Gooptu, Catherine M. Hawrylowicz, Catherine M. Hawrylowicz
Published 2021-08-01

In silico assessment of potential druggable pockets on the surface of α1-antitrypsin conformers.

by Anathe O M Patschull, Bibek Gooptu, Paul Ashford, Tina Daviter, Irene Nobeli
Published 2012-01-01

Non-invasive testing for liver pathology in alpha-1 antitrypsin deficiency

by John R Hurst, David A Lomas, Elisha Pickett, Douglas Thorburn, Aileen Marshall, Bibek Gooptu, Syed Hamza Abbas
Published 2020-05-01

Three new alpha1-antitrypsin deficiency variants help to define a C-terminal region regulating conformational change and polymerization.

by Anna M Fra, Bibek Gooptu, Ilaria Ferrarotti, Elena Miranda, Roberta Scabini, Riccardo Ronzoni, Federica Benini, Luciano Corda, Daniela Medicina, Maurizio Luisetti, Luisa Schiaffonati
Published 2012-01-01

Use of peripheral neutrophil to lymphocyte ratio and peripheral monocyte levels to predict survival in fibrotic hypersensitivity pneumonitis (fHP): a multicentre retrospective coho...

by Andrew W Creamer, Shaney L Barratt, Huzaifa I Adamali, Michael Gibbons, Bibek Gooptu, Anna Duckworth, Rebecca Wollerton, Chris Scotton, Janet Fallon, Matthew Steward, Silan Fidan, Tom Nancarrow, Felix Alexander Woodhead
Published 2021-12-01

Reactive centre loop mutants of α-1-antitrypsin reveal position-specific effects on intermediate formation along the polymerization pathway

by Imran Haq, James A. Irving, Sarah V. Faull, Jennifer A. Dickens, Adriana Ordóñez, Didier Belorgey, Bibek Gooptu, David A. Lomas
Published 2013-06-01

Multi-center evaluation of baseline neutrophil-to-lymphocyte (NLR) ratio as an independent predictor of mortality and clinical risk stratifier in idiopathic pulmonary fibrosisResea...

by Theresia A. Mikolasch, Peter M. George, Jagdeep Sahota, Thomas Nancarrow, Shaney L. Barratt, Felix A. Woodhead, Vasilis Kouranos, Victoria S.A. Cope, Andrew W. Creamer, Silan Fidan, Balaji Ganeshan, Luke Hoy, John A. Mackintosh, Robert Shortman, Anna Duckworth, Janet Fallon, Helen Garthwaite, Melissa Heightman, Huzaifa I. Adamali, Sarah Lines, Thida Win, Rebecca Wollerton, Elisabetta A. Renzoni, Matthew Steward, Athol U. Wells, Michael Gibbons, Ashley M. Groves, Bibek Gooptu, Chris J. Scotton, Joanna C. Porter
Published 2023-01-01

Understanding the burden of interstitial lung disease post-COVID-19: the UK Interstitial Lung Disease-Long COVID Study (UKILD-Long COVID)

by R Gisli Jenkins, A John Simpson, Nicholas D Weatherley, Guilhem Collier, Jim M Wild, David R Thickett, Shaney L Barratt, Nazia Chaudhuri, Ling-Pei Ho, Lisa G Spencer, John F Blaikley, Fasihul Khan, Iain Stewart, John Kenneth Baillie, Rod Lawson, Simon R Johnson, Paul Beirne, Mark Spears, Laura Fabbri, Joseph Jacob, Mark G Jones, Bibek Gooptu, Rachel C Chambers, Philip L Molyneaux, Peter M George, Michael A Gibbons, Emma K Denneny, Joanna C Porter, Manuela Platé, Stephen M Bianchi, Chris E Brightling, Richard James Allen, Annemarie Docherty, Jane A Mitchell, Ian P Hall, Jonathan Brooke, Louise V Wain, Malcolm Semple, Raminder Aul, Neil A Hanley, Krisnah Poinasamy, Pilar Rivera-Ortega, DJF Smith, Stefan C Stanel, A A Roger Thompson, Simon LF Walsh, Mark Everard Weeks, Dan G Wootton, Karen Piper Hanley
Published 2021-11-01

Mycophenolate and azathioprine efficacy in interstitial lung disease: a systematic review and meta-analysis

by Sally Singh, Mark Jones, Michael Kreuter, Maria Molina-Molina, Imre Noth, Andrew Wilson, Martin Brutsche, Naftali Kaminski, Gary M Hunninghake, Michael Keane, Nazia Chaudhuri, Ian Forrest, Bruno Crestani, Fernando J Martinez, Mohsen Sadatsafavi, Luca Richeldi, Antje Prasse, Fasihul Khan, Iain Stewart, Steve Jones, Gisli Jenkins, Gauri Saini, David Turner, Killian Hurley, Lucilla Piccari, Andrew Palmer, Joseph A Lasky, Simon Hart, Joyce Lee, Anthony Gordon, John Blaikley, Kirsty Hett, Helmut Prosch, Elisabeth Bendstrup, Christopher Huntley, Helen Parfrey, Huzaifa Adamali, Paul Beirne, Stephen Bianchi, George Chalmers, Sophie Fletcher, Peter George, Michael Gibbons, Mark Spears, Laura Fabbri, Felix Chua, Michael Henry, Cormac McCarthy, Sabrina Paganoni, Joseph Jacob, Mark Toshner, Bibek Gooptu, Andrew Briggs, Philip L Molyneaux, Athol Wells, Charlotte Summers, Leticia Kawano-Dourado, Ian Glaspole, Melanie Quintana, Christopher J Ryerson, Paolo Spagnolo, Francesco Bonella, Carisi Anne Polanczyk, Anjali Crawshaw, Laurence Pearmain, Avinash Anil Nair, Raphaël Borie, Alexandre Biasi Cavalcanti, Emanuela Falaschetti, Jonathan Chung, James Eaden, Kate Johnson, Shaney Barratt, Chris Ryerson, Juergen Behr, Andreas Guenther, Nik Hirani, Karin Storrer, Deepak Talwar, Claudia Ravaglia, Katerina Antoniou, Sara Freitas, Carlo Vancheri, Laura Price, Amanda Goodwin, Daniel Chambers, Gunnar Gudmundsson, Roger Lewis, Ingrid Cox, Anne Holland, Erica Farrand, Argyrios Tzouvelekis, Rui Rolo, Duncan Richards, Larissa Schwarzkopf, Sabina Guler, Devesh Dhasmana, Claudia Valenzuela, John S Kim, Louise Crowley, Lisa Watson, Amanda Bravery, Elisabetta Balestro, Wendy Adams, Francesco Lombardi, Ali Mojibian, Ana Etges, Ana Sousa Marcelino Boshoff, Anne Bergeron Anna-MariaHoffmann-Vold, Athina Trachalaki, Barbara Wendelberger, Bhavika Kaul Ben Hope-Gill, Bruno Baldi, Carlos Robalo, Chris Grainge, Christophe von Garnier, Conal Hayton, Dapeng Wang, Daphne Bablis, David Thicket, Deji Adegunsoye, Devaraj Anand, Dhruv Parek, Diane Griffiths, Eliana Santucci, Eliza Tsitoura, Emma Karlsen, Ena Gupta, Harold Collard, Hernan Fainberg, Iazsmin Bauer-Ventura, Irina Strambu, Jacobo Sellares, Janet Johnston, Jeff Swigris, Karina Negrelli, Katarzyna Lewandowska, Katrin Hostettler, Kerri Johannson, Liam Galvin, Lisa G. Spencer, Manuela Funke Chambour, Marlies Wijsenbeek-Lourens, Martina Vasakova, Milena Man Iuliu Hatieganu, Nick Weatherley, Ovidiu Fira Mladinescu Victor Babes, Peter Bryce, Pilar Rivera Ortega, Radu Crisan-Dabija, Rahul Maida, Sara Piciucchi, Shama Malik, Simone Dal Corso, Stefan Stanel
Published 2024-04-01