A comparison of software for analysis of rare and common short tandem repeat (STR) variation using human genome sequences from clinical and population-based samples

by John W. Oketch, Louise V. Wain, Edward J. Hollox
Published 2024-01-01

Shared genetic risk factors: implications for treatment of idiopathic pulmonary fibrosis and systemic hypertension

by Gina Parcesepe, Richard J. Allen, Beatriz Guillen-Guio, Samuel Moss, R. Gisli Jenkins, Louise V. Wain
Published 2023-11-01

Genome-wide gene-air pollution interaction analysis of lung function in 300,000 individuals

by Carl A. Melbourne, A. Mesut Erzurumluoglu, Nick Shrine, Jing Chen, Martin D. Tobin, Anna L. Hansell, Louise V. Wain
Published 2022-01-01

Exome-wide analysis of copy number variation shows association of the human leukocyte antigen region with asthma in UK Biobank

by Katherine A. Fawcett, German Demidov, Nick Shrine, Megan L. Paynton, Stephan Ossowski, Ian Sayers, Louise V. Wain, Edward J. Hollox
Published 2022-05-01

Shared genetic etiology between idiopathic pulmonary fibrosis and COVID-19 severity

by João Fadista, Luke M. Kraven, Juha Karjalainen, Shea J. Andrews, Frank Geller, J Kenneth Baillie, Louise V. Wain, R.Gisli Jenkins, Bjarke Feenstra
Published 2021-03-01

Targeted Sequencing of Lung Function Loci in Chronic Obstructive Pulmonary Disease Cases and Controls.

by María Soler Artigas, Louise V Wain, Nick Shrine, Tricia M McKeever, UK BiLEVE, Ian Sayers, Ian P Hall, Martin D Tobin
Published 2017-01-01

Mapping brain endophenotypes associated with idiopathic pulmonary fibrosis genetic riskResearch in context

by Ali-Reza Mohammadi-Nejad, Richard J. Allen, Luke M. Kraven, Olivia C. Leavy, R. Gisli Jenkins, Louise V. Wain, Dorothee P. Auer, Stamatios N. Sotiropoulos
Published 2022-12-01

Human CCL3L1 copy number variation, gene expression, and the role of the CCL3L1-CCR5 axis in lung function [version 2; referees: 2 approved]

by Adeolu B. Adewoye, Nick Shrine, Linda Odenthal-Hesse, Samantha Welsh, Anders Malarstig, Scott Jelinsky, Iain Kilty, Martin D. Tobin, Edward J. Hollox, Louise V. Wain
Published 2018-04-01

Human CCL3L1 copy number variation, gene expression, and the role of the CCL3L1-CCR5 axis in lung function [version 1; referees: 2 approved]

by Adeolu B. Adewoye, Nick Shrine, Linda Odenthal-Hesse, Samantha Welsh, Anders Malarstig, Scott Jelinsky, Iain Kilty, Martin D. Tobin, Edward J. Hollox, Louise V. Wain
Published 2018-02-01

The role of copy number variation in susceptibility to amyotrophic lateral sclerosis: genome-wide association study and comparison with published loci.

by Louise V Wain, Inti Pedroso, John E Landers, Gerome Breen, Christopher E Shaw, P Nigel Leigh, Robert H Brown, Martin D Tobin, Ammar Al-Chalabi
Published 2009-12-01

Adjustment for index event bias in genome-wide association studies of subsequent events

by Frank Dudbridge, Richard J. Allen, Nuala A. Sheehan, A. Floriaan Schmidt, James C. Lee, R. Gisli Jenkins, Louise V. Wain, Aroon D. Hingorani, Riyaz S. Patel
Published 2019-04-01

A statistical framework to identify cell types whose genetically regulated proportions are associated with complex diseases.

by Wei Liu, Wenxuan Deng, Ming Chen, Zihan Dong, Biqing Zhu, Zhaolong Yu, Daiwei Tang, Maor Sauler, Chen Lin, Louise V Wain, Michael H Cho, Naftali Kaminski, Hongyu Zhao
Published 2023-07-01

Genetic correlation and causal relationships between cardio-metabolic traits and lung function impairment

by Matthias Wielscher, Andre F. S. Amaral, Diana van der Plaat, Louise V. Wain, Sylvain Sebert, David Mosen-Ansorena, Juha Auvinen, Karl-Heinz Herzig, Abbas Dehghan, Debbie L. Jarvis, Marjo-Riitta Jarvelin
Published 2021-06-01

Novel idiopathic pulmonary fibrosis susceptibility variants revealed by deep sequencing

by Jose M. Lorenzo-Salazar, Shwu-Fan Ma, Jonathan Jou, Pei-Chi Hou, Beatriz Guillen-Guio, Richard J. Allen, R. Gisli Jenkins, Louise V. Wain, Justin M. Oldham, Imre Noth, Carlos Flores
Published 2019-06-01

Prevalence, risk factors and treatments for post-COVID-19 breathlessness: a systematic review and meta-analysis

by Bang Zheng, Luke Daines, Qing Han, John R. Hurst, Paul Pfeffer, Manu Shankar-Hari, Omer Elneima, Samantha Walker, Jeremy S. Brown, Salman Siddiqui, Jennifer K. Quint, Christopher E. Brightling, Rachael A. Evans, Louise V. Wain, Liam G. Heaney, Aziz Sheikh
Published 2022-11-01

Pleiotropic associations of heterozygosity for the SERPINA1 Z allele in the UK Biobank

by Katherine A. Fawcett, Kijoung Song, Guoqing Qian, Aliki-Eleni Farmaki, Richard Packer, Catherine John, Nick Shrine, Raquel Granell, Sue Ring, Nicholas J. Timpson, Laura M. Yerges-Armstrong, Richard Eastell, Louise V. Wain, Robert A. Scott, Martin D. Tobin, Ian P. Hall
Published 2021-05-01

Copy number variation of the beta-defensin genes in europeans: no supporting evidence for association with lung function, chronic obstructive pulmonary disease or asthma.

by Louise V Wain, Linda Odenthal-Hesse, Razan Abujaber, Ian Sayers, Caroline Beardsmore, Erol A Gaillard, Sally Chappell, Cristian M Dogaru, Tricia McKeever, Tamar Guetta-Baranes, Noor Kalsheker, Claudia E Kuehni, Ian P Hall, Martin D Tobin, Edward J Hollox
Published 2014-01-01

GSTCD and INTS12 regulation and expression in the human lung.

by Ma'en Obeidat, Suzanne Miller, Kelly Probert, Charlotte K Billington, Amanda P Henry, Emily Hodge, Carl P Nelson, Ceri E Stewart, Caroline Swan, Louise V Wain, María Soler Artigas, Erik Melén, Kevin Ushey, Ke Hao, Maxime Lamontagne, Yohan Bossé, Dirkje S Postma, Martin D Tobin, Ian Sayers, Ian P Hall
Published 2013-01-01

Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction.

by Louise V Wain, Ian Sayers, María Soler Artigas, Michael A Portelli, Eleftheria Zeggini, Ma'en Obeidat, Don D Sin, Yohan Bossé, David Nickle, Corry-Anke Brandsma, Anders Malarstig, Ciara Vangjeli, Scott A Jelinsky, Sally John, Iain Kilty, Tricia McKeever, Nick R G Shrine, James P Cook, Shrina Patel, Tim D Spector, Edward J Hollox, Ian P Hall, Martin D Tobin
Published 2014-05-01

Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis

by Ryan S. Dhindsa, Johan Mattsson, Abhishek Nag, Quanli Wang, Louise V. Wain, Richard Allen, Eleanor M. Wigmore, Kristina Ibanez, Dimitrios Vitsios, Sri V. V. Deevi, Sebastian Wasilewski, Maria Karlsson, Glenda Lassi, Henric Olsson, Daniel Muthas, Susan Monkley, Alex Mackay, Lynne Murray, Simon Young, Carolina Haefliger, FinnGen Consortium, Toby M. Maher, Maria G. Belvisi, Gisli Jenkins, Philip L. Molyneaux, Adam Platt, Slavé Petrovski
Published 2021-03-01