Regulated aggregative multicellularity in a close unicellular relative of metazoa

by Arnau Sebé-Pedrós, Manuel Irimia, Javier del Campo, Helena Parra-Acero, Carsten Russ, Chad Nusbaum, Benjamin J Blencowe, Iñaki Ruiz-Trillo
Published 2013-12-01

Massively parallel sequencing of human urinary exosome/microvesicle RNA reveals a predominance of non-coding RNA.

by Kevin C Miranda, Daniel T Bond, Joshua Z Levin, Xian Adiconis, Andrey Sivachenko, Carsten Russ, Dennis Brown, Chad Nusbaum, Leileata M Russo
Published 2014-01-01

A Genome-wide CRISPR Screen Identifies ZCCHC14 as a Host Factor Required for Hepatitis B Surface Antigen Production

by Anastasia Hyrina, Christopher Jones, Darlene Chen, Scott Clarkson, Nadire Cochran, Paul Feucht, Gregory Hoffman, Alicia Lindeman, Carsten Russ, Frederic Sigoillot, Tiffany Tsang, Kyoko Uehara, Lili Xie, Don Ganem, Meghan Holdorf
Published 2019-12-01

USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin

by Lei Ji, Bo Lu, Raffaella Zamponi, Olga Charlat, Robert Aversa, Zinger Yang, Frederic Sigoillot, Xiaoping Zhu, Tiancen Hu, John S. Reece-Hoyes, Carsten Russ, Gregory Michaud, Jan S. Tchorz, Xiaomo Jiang, Feng Cong
Published 2019-09-01

TRIAMF: A New Method for Delivery of Cas9 Ribonucleoprotein Complex to Human Hematopoietic Stem Cells

by Jonathan Yen, Michael Fiorino, Yi Liu, Steve Paula, Scott Clarkson, Lisa Quinn, William R. Tschantz, Heath Klock, Ning Guo, Carsten Russ, Vionnie W. C. Yu, Craig Mickanin, Susan C. Stevenson, Cameron Lee, Yi Yang
Published 2018-11-01

Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC

by Hao Zeng, Johnny Castillo-Cabrera, Mika Manser, Bo Lu, Zinger Yang, Vaik Strande, Damien Begue, Raffaella Zamponi, Shumei Qiu, Frederic Sigoillot, Qiong Wang, Alicia Lindeman, John S Reece-Hoyes, Carsten Russ, Debora Bonenfant, Xiaomo Jiang, Youzhen Wang, Feng Cong
Published 2019-11-01

Quantitative deep sequencing reveals dynamic HIV-1 escape and large population shifts during CCR5 antagonist therapy in vivo.

by Athe M N Tsibris, Bette Korber, Ramy Arnaout, Carsten Russ, Chien-Chi Lo, Thomas Leitner, Brian Gaschen, James Theiler, Roger Paredes, Zhaohui Su, Michael D Hughes, Roy M Gulick, Wayne Greaves, Eoin Coakley, Charles Flexner, Chad Nusbaum, Daniel R Kuritzkes
Published 2009-05-01

The Natural Product Cavinafungin Selectively Interferes with Zika and Dengue Virus Replication by Inhibition of the Host Signal Peptidase

by David Estoppey, Chia Min Lee, Marco Janoschke, Boon Heng Lee, Kah Fei Wan, Hongping Dong, Philippe Mathys, Ireos Filipuzzi, Tim Schuhmann, Ralph Riedl, Thomas Aust, Olaf Galuba, Gregory McAllister, Carsten Russ, Martin Spiess, Tewis Bouwmeester, Ghislain M.C. Bonamy, Dominic Hoepfner
Published 2017-04-01

Cell adhesion molecule KIRREL1 is a feedback regulator of Hippo signaling recruiting SAV1 to cell-cell contact sites

by Atanu Paul, Stefano Annunziato, Bo Lu, Tianliang Sun, Olivera Evrova, Lara Planas-Paz, Vanessa Orsini, Luigi M. Terracciano, Olga Charlat, Zinger Yang Loureiro, Lei Ji, Raffaella Zamponi, Frederic Sigoillot, Hong Lei, Alicia Lindeman, Carsten Russ, John S. Reece-Hoyes, Thomas B. Nicholson, Jan S. Tchorz, Feng Cong
Published 2022-02-01

Cancer lineage-specific regulation of YAP responsive elements revealed through large-scale functional epigenomic screens

by Inês A. M. Barbosa, Rajaraman Gopalakrishnan, Samuele Mercan, Thanos P. Mourikis, Typhaine Martin, Simon Wengert, Caibin Sheng, Fei Ji, Rui Lopes, Judith Knehr, Marc Altorfer, Alicia Lindeman, Carsten Russ, Ulrike Naumann, Javad Golji, Kathleen Sprouffske, Louise Barys, Luca Tordella, Dirk Schübeler, Tobias Schmelzle, Giorgio G. Galli
Published 2023-07-01

Genome-wide CRISPR screen identifies protein pathways modulating tau protein levels in neurons

by Carlos G. Sanchez, Christopher M. Acker, Audrey Gray, Malini Varadarajan, Cheng Song, Nadire R. Cochran, Steven Paula, Alicia Lindeman, Shaojian An, Gregory McAllister, John Alford, John Reece-Hoyes, Carsten Russ, Lucas Craig, Ketthsy Capre, Christian Doherty, Gregory R. Hoffman, Sarah J. Luchansky, Manuela Polydoro, Ricardo Dolmetsch, Fiona Elwood
Published 2021-06-01

Genome-Scale CRISPR Screens Identify Human Pluripotency-Specific Genes

by Robert J. Ihry, Max R. Salick, Daniel J. Ho, Marie Sondey, Sravya Kommineni, Steven Paula, Joe Raymond, Beata Henry, Elizabeth Frias, Qiong Wang, Kathleen A. Worringer, Chaoyang Ye, Carsten Russ, John S. Reece-Hoyes, Robert C. Altshuler, Ranjit Randhawa, Zinger Yang, Gregory McAllister, Gregory R. Hoffman, Ricardo Dolmetsch, Ajamete Kaykas
Published 2019-04-01

An iron-dependent metabolic vulnerability underlies VPS34-dependence in RKO cancer cells.

by Marek J Kobylarz, Jonathan M Goodwin, Zhao B Kang, John W Annand, Sarah Hevi, Ellen O'Mahony, Gregory McAllister, John Reece-Hoyes, Qiong Wang, John Alford, Carsten Russ, Alicia Lindeman, Martin Beibel, Guglielmo Roma, Walter Carbone, Judith Knehr, Joseph Loureiro, Christophe Antczak, Dmitri Wiederschain, Leon O Murphy, Suchithra Menon, Beat Nyfeler
Published 2020-01-01

Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62

by Rowena DeJesus, Francesca Moretti, Gregory McAllister, Zuncai Wang, Phil Bergman, Shanming Liu, Elizabeth Frias, John Alford, John S Reece-Hoyes, Alicia Lindeman, Jennifer Kelliher, Carsten Russ, Judith Knehr, Walter Carbone, Martin Beibel, Guglielmo Roma, Aylwin Ng, John A Tallarico, Jeffery A Porter, Ramnik J Xavier, Craig Mickanin, Leon O Murphy, Gregory R Hoffman, Beat Nyfeler
Published 2016-06-01

IRF2 is a master regulator of human keratinocyte stem cell fate

by Nicolas Mercado, Gabi Schutzius, Christian Kolter, David Estoppey, Sebastian Bergling, Guglielmo Roma, Caroline Gubser Keller, Florian Nigsch, Adrian Salathe, Remi Terranova, John Reece-Hoyes, John Alford, Carsten Russ, Judith Knehr, Dominic Hoepfner, Alexandra Aebi, Heinz Ruffner, Tanner C. Beck, Sajjeev Jagannathan, Calla M. Olson, Hadley E. Sheppard, Selma Z. Elsarrag, Tewis Bouwmeester, Mathias Frederiksen, Felix Lohmann, Charles Y. Lin, Susan Kirkland
Published 2019-10-01

Structure of the germline genome of Tetrahymena thermophila and relationship to the massively rearranged somatic genome

by Eileen P Hamilton, Aurélie Kapusta, Piroska E Huvos, Shelby L Bidwell, Nikhat Zafar, Haibao Tang, Michalis Hadjithomas, Vivek Krishnakumar, Jonathan H Badger, Elisabet V Caler, Carsten Russ, Qiandong Zeng, Lin Fan, Joshua Z Levin, Terrance Shea, Sarah K Young, Ryan Hegarty, Riza Daza, Sharvari Gujja, Jennifer R Wortman, Bruce W Birren, Chad Nusbaum, Jainy Thomas, Clayton M Carey, Ellen J Pritham, Cédric Feschotte, Tomoko Noto, Kazufumi Mochizuki, Romeo Papazyan, Sean D Taverna, Paul H Dear, Donna M Cassidy-Hanley, Jie Xiong, Wei Miao, Eduardo Orias, Robert S Coyne
Published 2016-11-01

Distinctive expansion of potential virulence genes in the genome of the oomycete fish pathogen Saprolegnia parasitica.

by Rays H Y Jiang, Irene de Bruijn, Brian J Haas, Rodrigo Belmonte, Lars Löbach, James Christie, Guido van den Ackerveken, Arnaud Bottin, Vincent Bulone, Sara M Díaz-Moreno, Bernard Dumas, Lin Fan, Elodie Gaulin, Francine Govers, Laura J Grenville-Briggs, Neil R Horner, Joshua Z Levin, Marco Mammella, Harold J G Meijer, Paul Morris, Chad Nusbaum, Stan Oome, Andrew J Phillips, David van Rooyen, Elzbieta Rzeszutek, Marcia Saraiva, Chris J Secombes, Michael F Seidl, Berend Snel, Joost H M Stassen, Sean Sykes, Sucheta Tripathy, Herbert van den Berg, Julio C Vega-Arreguin, Stephan Wawra, Sarah K Young, Qiandong Zeng, Javier Dieguez-Uribeondo, Carsten Russ, Brett M Tyler, Pieter van West
Published 2013-06-01

Identification of RNA splicing errors resulting in human ornithine transcarbamylase deficiency

by Carstens, Russ P.
Published 1990

Deep-learning augmented RNA-seq analysis of transcript splicing.

by Zhang, Zijun, Pan, Zhicheng, Ying, Yi, Xie, Zhijie, Adhikari, Samir, Phillips, John, Carstens, Russ P, Black, Douglas L, Wu, Yingnian, Xing, Yi
Published 2019

ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation.

by Bhate, Amruta, Parker, Darren J, Bebee, Thomas W, Ahn, Jaegyoon, Arif, Waqar, Rashan, Edrees H, Chorghade, Sandip, Chau, Anthony, Lee, Jae-Hyung, Anakk, Sayeepriyadarshini, Carstens, Russ P, Xiao, Xinshu, Kalsotra, Auinash
Published 2015