Genome-wide CRISPR-Cas9 screens identify mechanisms of BET bromodomain inhibitor sensitivity

by David Estoppey, Gabi Schutzius, Christian Kolter, Adrian Salathe, Tiffany Wunderlin, Amandine Meyer, Florian Nigsch, Tewis Bouwmeester, Dominic Hoepfner, Susan Kirkland
Published 2021-11-01

R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5.

by Heinz Ruffner, Joëlle Sprunger, Olga Charlat, Juliet Leighton-Davies, Bianka Grosshans, Adrian Salathe, Svenja Zietzling, Valérie Beck, Maxime Therier, Andrea Isken, Yang Xie, Yue Zhang, Huaixiang Hao, Xiaoying Shi, Dong Liu, Qinhui Song, Ieuan Clay, Gabriele Hintzen, Jan Tchorz, Laure C Bouchez, Gregory Michaud, Peter Finan, Vic E Myer, Tewis Bouwmeester, Jeff Porter, Marc Hild, Fred Bassilana, Christian N Parker, Feng Cong
Published 2012-01-01

IRF2 is a master regulator of human keratinocyte stem cell fate

by Nicolas Mercado, Gabi Schutzius, Christian Kolter, David Estoppey, Sebastian Bergling, Guglielmo Roma, Caroline Gubser Keller, Florian Nigsch, Adrian Salathe, Remi Terranova, John Reece-Hoyes, John Alford, Carsten Russ, Judith Knehr, Dominic Hoepfner, Alexandra Aebi, Heinz Ruffner, Tanner C. Beck, Sajjeev Jagannathan, Calla M. Olson, Hadley E. Sheppard, Selma Z. Elsarrag, Tewis Bouwmeester, Mathias Frederiksen, Felix Lohmann, Charles Y. Lin, Susan Kirkland
Published 2019-10-01