Normal and tumor-derived organoids as a drug screening platform for tumor-specific drug vulnerabilities

by Camilla Calandrini, Jarno Drost
Published 2022-03-01

Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors

by Camilla Calandrini, Sander R. van Hooff, Irene Paassen, Dilara Ayyildiz, Sepide Derakhshan, M. Emmy M. Dolman, Karin P.S. Langenberg, Marieke van de Ven, Cecilia de Heus, Nalan Liv, Marcel Kool, Ronald R. de Krijger, Godelieve A.M. Tytgat, Marry M. van den Heuvel-Eibrink, Jan J. Molenaar, Jarno Drost
Published 2021-08-01

Somatic mutations and single-cell transcriptomes reveal the root of malignant rhabdoid tumours

by Lars Custers, Eleonora Khabirova, Tim H. H. Coorens, Thomas R. W. Oliver, Camilla Calandrini, Matthew D. Young, Felipe A. Vieira Braga, Peter Ellis, Lira Mamanova, Heidi Segers, Arie Maat, Marcel Kool, Eelco W. Hoving, Marry M. van den Heuvel-Eibrink, James Nicholson, Karin Straathof, Liz Hook, Ronald R. de Krijger, Claire Trayers, Kieren Allinson, Sam Behjati, Jarno Drost
Published 2021-03-01

An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity

by Camilla Calandrini, Frans Schutgens, Rurika Oka, Thanasis Margaritis, Tito Candelli, Luka Mathijsen, Carola Ammerlaan, Ravian L. van Ineveld, Sepide Derakhshan, Sanne de Haan, Emmy Dolman, Philip Lijnzaad, Lars Custers, Harry Begthel, Hindrik H. D. Kerstens, Lindy L. Visser, Maarten Rookmaaker, Marianne Verhaar, Godelieve A. M. Tytgat, Patrick Kemmeren, Ronald R. de Krijger, Reem Al-Saadi, Kathy Pritchard-Jones, Marcel Kool, Anne C. Rios, Marry M. van den Heuvel-Eibrink, Jan J. Molenaar, Ruben van Boxtel, Frank C. P. Holstege, Hans Clevers, Jarno Drost
Published 2020-03-01

Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes

by Michael T Meister, Marian J A Groot Koerkamp, Terezinha deSouza, Willemijn B Breunis, Ewa Frazer‐Mendelewska, Mariël Brok, Jeff DeMartino, Freek Manders, Camilla Calandrini, Hinri H D Kerstens, Alex Janse, M Emmy M Dolman, Selma Eising, Karin P S Langenberg, Marc vanTuil, Rutger R G Knops, Sheila Terwisscha vanScheltinga, Laura S Hiemcke‐Jiwa, Uta Flucke, Johannes H M Merks, Max M vanNoesel, Bastiaan B J Tops, Jayne Y Hehir‐Kwa, Patrick Kemmeren, Jan J Molenaar, Marc van deWetering, Ruben vanBoxtel, Jarno Drost, Frank C P Holstege
Published 2022-10-01

Variant-specific pathophysiological mechanisms of AFF3 differently influence transcriptome profiles

by Sissy Bassani, Jacqueline Chrast, Giovanna Ambrosini, Norine Voisin, Frédéric Schütz, Alfredo Brusco, Fabio Sirchia, Lydia Turban, Susanna Schubert, Rami Abou Jamra, Jan-Ulrich Schlump, Desiree DeMille, Pinar Bayrak-Toydemir, Gary Rex Nelson, Kristen Nicole Wong, Laura Duncan, Mackenzie Mosera, Christian Gilissen, Lisenka E. L. M. Vissers, Rolph Pfundt, Rogier Kersseboom, Hilde Yttervik, Geir Åsmund Myge Hansen, Marie Falkenberg Smeland, Kameryn M. Butler, Michael J. Lyons, Claudia M. B. Carvalho, Chaofan Zhang, James R. Lupski, Lorraine Potocki, Leticia Flores-Gallegos, Rodrigo Morales-Toquero, Florence Petit, Binnaz Yalcin, Annabelle Tuttle, Houda Zghal Elloumi, Lane McCormick, Mary Kukolich, Oliver Klaas, Judit Horvath, Marcello Scala, Michele Iacomino, Francesca Operto, Federico Zara, Karin Writzl, Aleš Maver, Maria K. Haanpää, Pia Pohjola, Harri Arikka, Anneke J. A. Kievit, Camilla Calandrini, Christian Iseli, Nicolas Guex, Alexandre Reymond
Published 2024-05-01