Bifunctional anti-huntingtin proteasome-directed intrabodies mediate efficient degradation of mutant huntingtin exon 1 protein fragments.

by David C Butler, Anne Messer
Published 2011-01-01

Optimizing intracellular antibodies (intrabodies/nanobodies) to treat neurodegenerative disorders

by Anne Messer, David C. Butler
Published 2020-02-01

Nicotinamide improves motor deficits and upregulates PGC-1α and BDNF gene expression in a mouse model of Huntington's disease

by Tyisha Hathorn, Abigail Snyder-Keller, Anne Messer
Published 2011-01-01

Conformational targeting of fibrillar polyglutamine proteins in live cells escalates aggregation and cytotoxicity.

by Erik Kvam, Brent L Nannenga, Min S Wang, Zongjian Jia, Michael R Sierks, Anne Messer
Published 2009-05-01

Bifunctional Anti-Non-Amyloid Component α-Synuclein Nanobodies Are Protective In Situ.

by David C Butler, Shubhada N Joshi, Erwin De Genst, Ankit S Baghel, Christopher M Dobson, Anne Messer
Published 2016-01-01

A human single-chain Fv intrabody preferentially targets amino-terminal huntingtin fragments in striatal models of Huntington's disease

by Todd W. Miller, Chun Zhou, Silvia Gines, Marcy E. MacDonald, Nicholas D. Mazarakis, Gillian P. Bates, James S. Huston, Anne Messer
Published 2005-06-01

Correction: Sustained AAV9-mediated expression of a non-self protein in the CNS of non-human primates after immunomodulation.

by Arlene I Ramsingh, Steven J Gray, Andrew Reilly, Michael Koday, Debbie Bratt, Merika Treants Koday, Paul Munson, Robert Murnane, Jeremy Smedley, Yuhui Hu, Anne Messer, Deborah Heydenburg Fuller
Published 2018-01-01

Sustained AAV9-mediated expression of a non-self protein in the CNS of non-human primates after immunomodulation.

by Arlene I Ramsingh, Steven J Gray, Andrew Reilly, Michael Koday, Debbie Bratt, Merika Treants Koday, Paul Munson, Robert Murnane, Jeremy Smedley, Yuhui Hu, Anne Messer, Deborah Heydenburg Fuller
Published 2018-01-01

MSH3 polymorphisms and protein levels affect CAG repeat instability in Huntington's disease mice.

by Stéphanie Tomé, Kevin Manley, Jodie P Simard, Greg W Clark, Meghan M Slean, Meera Swami, Peggy F Shelbourne, Elisabeth R M Tillier, Darren G Monckton, Anne Messer, Christopher E Pearson
Published 2013-01-01

The relationship between entomological indicators of Aedes aegypti abundance and dengue virus infection.

by Cromwell, Elizabeth A, Stoddard, Steven T, Barker, Christopher M, Van Rie, Annelies, Messer, William B, Meshnick, Steven R, Morrison, Amy C, Scott, Thomas W
Published 2017