Ketosis versus carbotoxicity – metabolism determines the outcome of cancer immunotherapy

by Aitziber Buqué, Lorenzo Galluzzi, Guido Kroemer
Published 2021-01-01

Nicotinamide drives T cell activation in the mammary tumor microenvironment

by Yang Hu, Norma Bloy, Olivier Elemento, Aitziber Buqué
Published 2022-06-01

PT-112 induces immunogenic cell death and synergizes with immune checkpoint blockers in mouse tumor models

by Takahiro Yamazaki, Aitziber Buqué, Tyler D. Ames, Lorenzo Galluzzi
Published 2020-01-01

Apoptotic caspases cut down the immunogenicity of radiation

by Aitziber Buqué, Maria Esperanza Rodriguez-Ruiz, Jitka Fucikova, Lorenzo Galluzzi
Published 2019-11-01

NK cells beat T cells at early breast cancer control

by Aitziber Buque, Norma Bloy, Giulia Petroni, Guido Kroemer, Lorenzo Galluzzi
Published 2020-01-01

Immunofluorescence microscopy-based assessment of cytosolic DNA accumulation in mammalian cells

by Ai Sato, Aitziber Buque, Takahiro Yamazaki, Norma Bloy, Giulia Petroni, Lorenzo Galluzzi
Published 2021-06-01

733 Immunological mechanisms of resistance to CDK4/CDK6 inhibitors in breast cancer

by Silvia Formenti, Lorenzo Galluzzi, Aitziber Buqué Martinez, Giulia Petroni, Kenneth Gouin, Simon Knott
Published 2021-11-01

1440 Shaping the immunometabolism of HR+ breast cancer with kynurenamines

by Aitziber Buqué Martinez, Ai Sato, Norma Bloy, Laura Santambrogio, Cristina Clement, Madhur Shetty
Published 2023-11-01

858 Breaking through the resistance of breast cancer to immune checkpoint blockers in a unique mouse model of HR+ disease

by Silvia Formenti, Lorenzo Galluzzi, Takahiro Yamazaki, Giulia Petroni, Claudia Galassi, Ai Sato, Norma Bloy, Aitziber Buqué, Cristina Iribarren
Published 2023-11-01

Anticancer effects of anti-CD47 immunotherapy in vivo

by Kristina Iribarren, Aitziber Buque, Laura Mondragon, Wei Xie, Sarah Lévesque, Jonathan Pol, Laurence Zitvogel, Oliver Kepp, Guido Kroemer
Published 2019-03-01

285 Breaking through the resistance of breast cancer to immune checkpoint blockers in a unique mouse model of HR+ disease

by Silvia Formenti, Lorenzo Galluzzi, Takahiro Yamazaki, Aitziber Buqué Martinez, Giulia Petroni, Olivier Elemento, Ai Sato, Norma Bloy, Bhavneet Binder
Published 2021-11-01

Thymidylate synthase expression determines pemetrexed targets and resistance development in tumour cells.

by Aitziber Buqué, Unai Aresti, Begoña Calvo, Jangi Sh Muhialdin, Alberto Muñoz, Sergio Carrera, Eider Azkona, Itziar Rubio, Guillermo López-Vivanco
Published 2013-01-01

Cellular senescence in the response of HR+ breast cancer to radiotherapy and CDK4/6 inhibitors

by Vanessa Klapp, Aitziber Buqué, Norma Bloy, Ai Sato, Takahiro Yamazaki, Xi Kathy Zhou, Silvia C. Formenti, Lorenzo Galluzzi, Giulia Petroni
Published 2023-02-01

Apoptotic caspases inhibit abscopal responses to radiation and identify a new prognostic biomarker for breast cancer patients

by Maria Esperanza Rodriguez-Ruiz, Aitziber Buqué, Michal Hensler, Jonathan Chen, Norma Bloy, Giulia Petroni, Ai Sato, Takahiro Yamazaki, Jitka Fucikova, Lorenzo Galluzzi
Published 2019-11-01

560 Immunotherapeutic and antimetastatic activity of LTX-315 in preclinical models of ICI-resistant breast cancer

by Xi Zhou, Sandra Demaria, Baldur Sveinbjörnsson, Öystein Rekdal, Erik Wennerberg, Lorenzo Galluzzi, Takahiro Yamazaki, Michal Hensler, Jitka Fucikova, Aitziber Buqué Martinez, Jeffrey Kraynak
Published 2021-11-01

LTX-315-enabled, radiotherapy-boosted immunotherapeutic control of breast cancer by NK cells

by Takahiro Yamazaki, Erik Wennerberg, Michal Hensler, Aitziber Buqué, Jeffrey Kraynak, Jitka Fucikova, Xi Kathy Zhou, Baldur Sveinbjørnsson, Øystein Rekdal, Sandra Demaria, Lorenzo Galluzzi
Published 2021-01-01

Estrogen receptor 1 gene expression and its combination with estrogen receptor 2 or aromatase expression predicts survival in non-small cell lung cancer.

by Unai Aresti, Sergio Carrera, Eluska Iruarrizaga, Natalia Fuente, Ines Marrodan, Abigail Ruiz de Lobera, Alberto Muñoz, Aitziber Buque, Elizabeth Condori, Irene Ugalde, Begoña Calvo, Guillermo López Vivanco
Published 2014-01-01

Trial Watch: Immunostimulation with recombinant cytokines for cancer therapy

by Elena García-Martínez, Melody Smith, Aitziber Buqué, Fernando Aranda, Francisco Ayala de la Peña, Alejandra Ivars, Manuel Sanchez Cánovas, Ma Angeles Vicente Conesa, Jitka Fucikova, Radek Spisek, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi
Published 2018-06-01

Leveraging immune resistance archetypes in solid cancer to inform next-generation anticancer therapies

by Fan Zhang, Brendan Horton, Marco Ruella, Vivek Verma, Abigail Overacre-Delgoffe, Kristin G Anderson, Jennifer L Guerriero, Teresa S Kim, David A Braun, Aitziber Buqué, Sarah B Gitto, Bridget P Keenan, Todd A Triplett, Omkara Veeranki
Published 2023-06-01

Publisher Correction: Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer

by Aitziber Buqué, Norma Bloy, Maria Perez-Lanzón, Kristina Iribarren, Juliette Humeau, Jonathan G. Pol, Sarah Levesque, Laura Mondragon, Takahiro Yamazaki, Ai Sato, Fernando Aranda, Sylvère Durand, Alexandre Boissonnas, Jitka Fucikova, Laura Senovilla, David Enot, Michal Hensler, Margerie Kremer, Gautier Stoll, Yang Hu, Chiara Massa, Silvia C. Formenti, Barbara Seliger, Olivier Elemento, Radek Spisek, Fabrice André, Laurence Zitvogel, Suzette Delaloge, Guido Kroemer, Lorenzo Galluzzi
Published 2020-09-01