Multiethnic Genetic Association Studies Improve Power for Locus Discovery

by Pulit, Sara L., Voight, Benjamin F., de Bakker, Paul I Wen
Published 2011

Comparative Modelling by Restraint-Based Conformational Sampling

by Furnham, Nicholas, de Bakker, Paul I Wen, Gore, Swanand, Burke, David F, Blundell, Tom L
Published 2010

Deleterious Alleles in the Human Genome Are on Average Younger Than Neutral Alleles of the Same Frequency

by Kiezun, Adam, Pulit, Sara L., Francioli, Laurent C., van Dijk, Freerk, Swertz, Morris, Boomsma, Dorret I., van Duijn, Cornelia M., Slagboom, P. Eline, van Ommen, G. J. B., Wijmenga, Cisca, de Bakker, Paul I Wen, Sunyaev, Shamil R.
Published 2013

Novel Loci for Metabolic Networks and Multi-Tissue Expression Studies Reveal Genes for Atherosclerosis

by Inouye, Michael, Ripatti, Samuli, Kettunen, Johannes, Lyytikäinen, Leo-Pekka, Oksala, Niku, Laurila, Pirkka-Pekka, Kangas, Antti J., Soininen, Pasi, Savolainen, Markku J., Viikari, Jorma, Kähönen, Mika, Perola, Markus, Salomaa, Veikko, Raitakari, Olli, Lehtimäki, Terho, Taskinen, Marja-Riitta, Järvelin, Marjo-Riitta, Ala-Korpela, Mika, Palotie, Aarno, de Bakker, Paul I Wen
Published 2013

Amino Acid Position 11 of HLA-DRβ1 is a Major Determinant of Chromosome 6p Association with Ulcerative Colitis

by Achkar, Jean-Paul, Klei, Lambertus, de Bakker, Paul I Wen, Bellone, Gaia, Rebert, Nancy, Scott, Regan, Lu, Ying, Regueiro, Miguel, Brzezinski, Aaron, Kamboh, M. Ilyas, Fiocchi, Claudio, Devlin, Bernie, Trucco, Massimo, Ringquist, Steven, Roeder, Kathryn, Duerr, Richard H
Published 2013

Common Variants in 40 Genes Assessed for Diabetes Incidence and Response to Metformin and Lifestyle Intervention in the Diabetes Prevention Program

by Jablonski, Kathleen A., McAteer, Jarred B., Franks, Paul W., Pollin, Toni I., Hanson, Robert L., Fowler, Sarah, Shuldiner, Alan R., Knowler, William C., de Bakker, Paul I Wen, Saxena, Richa, Altshuler, David Matthew, Florez, Jose Carlos
Published 2012

Effective Detection of Human Leukocyte Antigen Risk Alleles in Celiac Disease Using Tag Single Nucleotide Polymorphisms

by Monsuur, Alienke J., Zhernakova, Alexandra, Pinto, Dalila, Verduijn, Willem, Romanos, Jihane, Auricchio, Renata, Lopez, Ana, van Heel, David A., Crusius, J. Bart A, Wijmenga, Cisca, de Bakker, Paul I Wen
Published 2011

Common Genetic Variation Near the Phospholamban Gene Is Associated with Cardiac Repolarisation: Meta-Analysis of Three Genome-Wide Association Studies

by Nolte, Ilja M., Wallace, Chris, Newhouse, Stephen J., Waggott, Daryl, Fu, Jingyuan, Soranzo, Nicole, Gwilliam, Rhian, Deloukas, Panos, Savelieva, Irina, Zheng, Dongling, Dalageorgou, Chrysoula, Farrall, Martin, Samani, Nilesh J., Brown, Morris, Dominiczak, Anna, Lathrop, Mark, Zeggini, Eleftheria, Wain, Louise V., Eijgelsheim, Mark, Pfeufer, Arne, Sanna, Serena, Arking, Dan E., Asselbergs, Folkert W., Spector, Tim D., Carter, Nicholas D., Jeffery, Steve, Tobin, Martin, Caulfield, Mark, Snieder, Harold, Munroe, Patricia B., Jamshidi, Yalda, Connell, John, Newton-Cheh, Christopher Holmes, Rice, Kenneth Robert, de Bakker, Paul I Wen, Paterson, Andrew D.
Published 2012

Common Missense Variant in the Glucokinase Regulatory Protein Gene Is Associated With Increased Plasma Triglyceride and C-Reactive Protein but Lower Fasting Glucose Concentrations

by Orho-Melander, Marju, Melander, Olle, Guiducci, Candace, Perez-Martinez, Pablo, Corella, Dolores, Roos, Charlotta, Tewhey, Ryan, Rieder, Mark J., Hall, Jennifer, Abecasis, Goncalo, Tai, E. Shyong, Welch, Cullan, Arnett, Donna K., Lyssenko, Valeriya, Lindholm, Eero, Burtt, Noel, Voight, Benjamin F., Tucker, Katherine L., Hedner, Thomas, Tuomi, Tiinamaija, Isomaa, Bo, Eriksson, Karl-Fredrik, Taskinen, Marja-Riitta, Wahlstrand, Björn, Hughes, Thomas E., Parnell, Laurence D., Lai, Chao-Qiang, Berglund, Göran, Peltonen, Leena, Vartiainen, Erkki, Jousilahti, Pekka, Havulinna, Aki S., Salomaa, Veikko, Nilsson, Peter, Groop, Leif, Ordovas, Jose M., Kathiresan, Sekar, Saxena, Richa, de Bakker, Paul I Wen, Hirschhorn, Joel Naom, Altshuler, David Matthew
Published 2011

Modeling the Cumulative Genetic Risk for Multiple Sclerosis from Genome-Wide Association Data

by Wang, Joanne H, Pappas, Derek, Pelletier, Daniel, Kappos, Ludwig, Polman, Chris H, Matthews, Paul M, Hauser, Stephen L, Baranzini, Sergio E, Oksenberg, Jorge R, De Jager, Philip Lawrence, de Bakker, Paul I Wen, Chibnik, Lori, Hafler, David A.
Published 2011

Meta-Analysis of Genome-Wide Association Studies in Celiac Disease and Rheumatoid Arthritis Identifies Fourteen Non-HLA Shared Loci

by Zhernakova, Alexandra, Stahl, Eli A., Trynka, Gosia, Festen, Eleanora A., Franke, Lude, Westra, Harm-Jan, Fehrmann, Rudolf S. N., Kurreeman, Fina A. S., Thomson, Brian, Gupta, Namrata, Romanos, Jihane, McManus, Ross, Ryan, Anthony W., Turner, Graham, Brouwer, Elisabeth, Posthumus, Marcel D., Remmers, Elaine F., Tucci, Francesca, Toes, Rene, Grandone, Elvira, Mazzilli, Maria Cristina, Rybak, Anna, Cukrowska, Bozena, Coenen, Marieke J. H., Radstake, Timothy R. D. J., van Riel, Piet L. C. M., Li, Yonghong, Gregersen, Peter K., Worthington, Jane, Siminovitch, Katherine A., Klareskog, Lars, Huizinga, Tom W. J., Wijmenga, Cisca, Raychaudhuri, Soumya, de Bakker, Paul I Wen, Plenge, Robert M.
Published 2011

Concept, Design and Implementation of a Cardiovascular Gene-centric 50 K SNP Array for Large-scale Genomic Association Studies

by Keating, Brendan J., Tischfield, Sam, Murray, Sarah S., Bhangale, Tushar, Price, Thomas S., Glessner, Joseph T., Galver, Luana, Barrett, Jeffrey C., Grant, Struan F. A., Farlow, Deborah N., Chandrupatla, Hareesh R., Ajmal, Saad, Papanicolaou, George J., Guo, Yiran, Li, Mingyao, DerOhannessian, Stephanie, Bailey, Swneke D., Montpetit, Alexandre, Edmondson, Andrew C., Taylor, Kent, Gai, Xiaowu, Wang, Susanna S., Fornage, Myriam, Shaikh, Tamim, Groop, Leif, Boehnke, Michael, Hall, Alistair S., Hattersley, Andrew T., Frackelton, Edward, Patterson, Nick, Chiang, Charleston W. K., Kim, Cecelia E., Fabsitz, Richard R., Ouwehand, Willem, Munroe, Patricia, Caulfield, Mark, Drake, Thomas, Boerwinkle, Eric, Whitehead, A. Stephen, Cappola, Thomas P., Samani, Nilesh J., Lusis, A. Jake, Schadt, Eric, Wilson, James G., Koenig, Wolfgang, McCarthy, Mark I., Kathiresan, Sekar, Gabriel, Stacey B., Hakonarson, Hakon, Anand, Sonia S., Reilly, Muredach, Engert, James C., Nickerson, Deborah A., Rader, Daniel J., FitzGerald, Garret A., Reitsma, Pieter H., Hansen, Mark, de Bakker, Paul I Wen, Price, Alkes, Reich, David Emil, Hirschhorn, Joel Naom
Published 2012

GWAS Identifies Novel Susceptibility Loci on 6p21.32 and 21q21.3 for Hepatocellular Carcinoma in Chronic Hepatitis B Virus Carriers

by Li, Shengping, Qian, Ji, Zhao, Wanting, Dai, Juncheng, Bei, Jin-Xin, Foo, Jia Nee, McLaren, Paul J., Li, Zhiqiang, Yang, Jingmin, Shen, Feng, Yang, Jiamei, Li, Shuhong, Pan, Shandong, Li, Wenjin, Zhai, Xiangjun, Zhou, Boping, Shi, Lehua, Chen, Xinchun, Chu, Minjie, Yan, Yiqun, Cheng, Shuqun, Shen, Jiawei, Jia, Weihua, Liu, Jibin, Yang, Jiahe, Wen, Zujia, Li, Aijun, Zhang, Guoliang, Luo, Xianrong, Qin, Hongbo, Chen, Minshan, Lin, Dongxin, Shen, Hongbing, Wang, Hongyang, Zeng, Yi-Xin, Wu, Mengchao, Hu, Zhibin, Shi, Yongyong, Liu, Jianjun, Zhou, Weiping, Yang, Yuan, Liu, Li, Wang, Yi, Wang, Jun, Zhang, Ying, Wang, Hua, Jin, Li, He, Lin, de Bakker, Paul I. Wen
Published 2013