Deleterious Alleles in the Human Genome Are on Average Younger Than Neutral Alleles of the Same Frequency

by Kiezun, Adam, Pulit, Sara L., Francioli, Laurent C., van Dijk, Freerk, Swertz, Morris, Boomsma, Dorret I., van Duijn, Cornelia M., Slagboom, P. Eline, van Ommen, G. J. B., Wijmenga, Cisca, de Bakker, Paul I Wen, Sunyaev, Shamil R.
Published 2013

A high-quality human reference panel reveals the complexity and distribution of genomic structural variants

by Hehir-Kwa, Jayne Y., Marschall, Tobias, Kloosterman, Wigard P., Francioli, Laurent C., Baaijens, Jasmijn A., Dijkstra, Louis J., Abdellaoui, Abdel, Koval, Vyacheslav, Thung, Djie Tjwan, Wardenaar, René, Renkens, Ivo, Coe, Bradley P., Deelen, Patrick, de Ligt, Joep, Lameijer, Eric-Wubbo, van Dijk, Freerk, Hormozdiari, Fereydoun, Bovenberg, Jasper A., de Craen, Anton J. M., Beekman, Marian, Hofman, Albert, Willemsen, Gonneke, Wolffenbuttel, Bruce, Platteel, Mathieu, Du, Yuanping, Chen, Ruoyan, Cao, Hongzhi, Cao, Rui, Sun, Yushen, Cao, Jeremy Sujie, Neerincx, Pieter B. T., Dijkstra, Martijn, Byelas, George, Kanterakis, Alexandros, Bot, Jan, Vermaat, Martijn, Laros, Jeroen F. J., den Dunnen, Johan T., de Knijff, Peter, Karssen, Lennart C., van Leeuwen, Elisa M., Amin, Najaf, Rivadeneira, Fernando, Estrada, Karol, Hottenga, Jouke-Jan, Kattenberg, V. Mathijs, van Enckevort, David, Mei, Hailiang, Santcroos, Mark, van Schaik, Barbera D. C., Handsaker, Robert E., McCarroll, Steven A., Ko, Arthur, Sudmant, Peter, Nijman, Isaac J., Uitterlinden, André G., van Duijn, Cornelia M., Eichler, Evan E., de Bakker, Paul I. W., Swertz, Morris A., Wijmenga, Cisca, van Ommen, Gert-Jan B., Slagboom, P. Eline, Boomsma, Dorret I., Schönhuth, Alexander, Ye, Kai, Guryev, Victor
Published 2016

Improved imputation quality of low-frequency and rare variants in European samples using the ‘Genome of The Netherlands'

by Deelen, Patrick, Menelaou, Androniki, van Leeuwen, Elisabeth M, Kanterakis, Alexandros, van Dijk, Freerk, Medina-Gomez, Carolina, Francioli, Laurent C, Hottenga, Jouke Jan, Karssen, Lennart C, Estrada, Karol, Kreiner-Møller, Eskil, Rivadeneira, Fernando, van Setten, Jessica, Gutierrez-Achury, Javier, Westra, Harm-Jan, Franke, Lude, van Enckevort, David, Dijkstra, Martijn, Byelas, Heorhiy, van Duijn, Cornelia M, Swertz, Morris A, Neerincx, Pieter B T, Pulit, Sara L, Elbers, Clara C, Francesco Palamara, Pier, Pe'er, Itsik, Abdellaoui, Abdel, Kloosterman, Wigard P, van Oven, Mannis, Vermaat, Martijn, Li, Mingkun, Laros, Jeroen F J, Stoneking, Mark, de Knijff, Peter, Kayser, Manfred, Veldink, Jan H, van den Berg, Leonard H, den Dunnen, Johan T, Amin, Najaf, van der Velde, K Joeri, Jan Hottenga, Jouke, Kattenberg, Mathijs, van Schaik, Barbera D C, Bot, Jan, Nijman, Isaäuc J, Mei, Hailiang, Koval, Vyacheslav, Ye, Kai, Lameijer, Eric-Wubbo, Moed, Matthijs H, Hehir-Kwa, Jayne Y, Handsaker, Robert E, Sunyaev, Shamil R, Sohail, Mashaal, Hormozdiari, Fereydoun, Marschall, Tobias, Marschall, Schönhuth, Guryev, Victor, de Bakker, Paul I W, Slagboom, P Eline, Beekman, Marian B, de Craen, Anton J M, Suchiman, H Eka D, Hofman, Albert, van Duijn, Cornelia, Boomsma, Dorret I, Willemsen, Gonneke, Wolffenbuttel, Bruce H, Platteel, Mathieu, Pitts, Steven J, Potluri, Shobha, Cox, David R, Li, Qibin, Li, Yingrui, Du, Yuanping, Chen, Ruoyan, Cao, Hongzhi, Li, Ning, Cao, Sujie, Wang, Jun, Bovenberg, Jasper A, committee, Steering, Wijmenga, Cisca, van Ommen, Gertjan B
Published 2014

A framework for the detection of de novo mutations in family-based sequencing data

by Francioli, Laurent C, Cretu-Stancu, Mircea, Garimella, Kiran V, Fromer, Menachem, Kloosterman, Wigard P, Wijmenga, Cisca, Investigator, Principal, Swertz, Morris A, van Duijn, Cornelia M, Boomsma, Dorret I, Slagboom, PEline, van Ommen, Gertjan B, de Bakker, Paul IW, van Dijk, Freerk, Menelaou, Androniki, Neerincx, Pieter BT, Pulit, Sara L, Deelen, Patrick, Elbers, Clara C, Francesco Palamara, Pier, Pe'er, Itsik, Abdellaoui, Abdel, van Oven, Mannis, Vermaat, Martijn, Li, Mingkun, Laros, Jeroen FJ, Stoneking, Mark, de Knijff, Peter, Kayser, Manfred, Veldink, Jan H, van den Berg, Leonard H, Byelas, Heorhiy, den Dunnen, Johan T, Dijkstra, Martijn, Amin, Najaf, van der Velde, K Joeri, Hottenga, Jouke Jan, van Setten, Jessica, van Leeuwen, Elisabeth M, Kanterakis, Alexandros, Kattenberg, Mathijs, Karssen, Lennart C, van Schaik, Barbera DC, Bot, Jan, Nijman, Isaäc J, Renkens, Ivo, van Enckevort, David, Mei, Hailiang, Koval, Vyacheslav, Estrada, Karol, Medina-Gomez, Carolina, Ye, Kai, Lameijer, Eric-Wubbo, Moed, Matthijs H, Hehir-Kwa, Jayne Y, Handsaker, Robert E, McCarroll, Steven A, Sunyaev, Shamil R, Polak, Paz, Vuzman, Dana, Sohail, Mashaal, Hormozdiari, Fereydoun, Marschall, Tobias, Schönhuth, Alexander, Guryev, Victor, Slagboom, P Eline, Beekman, Marian B, de Craen, Anton JM, Suchiman, H Eka D, Hofman, Albert, Oostra, Ben, Isaacs, Aaron, Rivadeneira, Fernando, Uitterlinden, André G, Willemsen, Gonneke, Platteel, Mathieu, Pitts, Steven J, Potluri, Shobha, Sundar, Purnima, Cox, David R, Li, Qibin, Li, Yingrui, Du, Yuanping, Chen, Ruoyan, Cao, Hongzhi, Li, Ning, Cao, Sujie, Wang, Jun, Bovenberg, Jasper A, Brandsma, Margreet, Samocha, Kaitlin E, Neale, Benjamin M, Daly, Mark J, Banks, Eric, DePristo, Mark A
Published 2017

Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

by van Leeuwen, Elisabeth M., Karssen, Lennart C., Deelen, Joris, Isaacs, Aaron, Medina-Gomez, Carolina, Mbarek, Hamdi, Kanterakis, Alexandros, Trompet, Stella, Postmus, Iris, Verweij, Niek, van Enckevort, David J., Huffman, Jennifer E., White, Charles C., Feitosa, Mary F., Bartz, Traci M., Manichaikul, Ani, Joshi, Peter K., Peloso, Gina M., Deelen, Patrick, van Dijk, Freerk, Willemsen, Gonneke, de Geus, Eco J., Milaneschi, Yuri, Penninx, Brenda W.J.H., Francioli, Laurent C., Menelaou, Androniki, Pulit, Sara L., Rivadeneira, Fernando, Hofman, Albert, Oostra, Ben A., Franco, Oscar H., Leach, Irene Mateo, Beekman, Marian, de Craen, Anton J.M., Uh, Hae-Won, Trochet, Holly, Hocking, Lynne J., Porteous, David J., Sattar, Naveed, Packard, Chris J., Buckley, Brendan M., Brody, Jennifer A., Bis, Joshua C., Rotter, Jerome I., Mychaleckyj, Josyf C., Campbell, Harry, Duan, Qing, Lange, Leslie A., Wilson, James F., Hayward, Caroline, Polasek, Ozren, Vitart, Veronique, Rudan, Igor, Wright, Alan F., Rich, Stephen S., Psaty, Bruce M., Borecki, Ingrid B., Kearney, Patricia M., Stott, David J., Adrienne Cupples, L., Neerincx, Pieter B.T., Elbers, Clara C., Francesco Palamara, Pier, Pe'er, Itsik, Abdellaoui, Abdel, Kloosterman, Wigard P., van Oven, Mannis, Vermaat, Martijn, Li, Mingkun, Laros, Jeroen F.J., Stoneking, Mark, de Knijff, Peter, Kayser, Manfred, Veldink, Jan H., van den Berg, Leonard H., Byelas, Heorhiy, den Dunnen, Johan T., Dijkstra, Martijn, Amin, Najaf, Joeri van der Velde, K., van Setten, Jessica, Kattenberg, Mathijs, van Schaik, Barbera D.C., Bot, Jan, Nijman, Isaäc J., Mei, Hailiang, Koval, Vyacheslav, Ye, Kai, Lameijer, Eric-Wubbo, Moed, Matthijs H., Hehir-Kwa, Jayne Y., Handsaker, Robert E., Sunyaev, Shamil R., Sohail, Mashaal, Hormozdiari, Fereydoun, Marschall, Tobias, Schönhuth, Alexander, Guryev, Victor, Suchiman, H. Eka D., Wolffenbuttel, Bruce H., Platteel, Mathieu, Pitts, Steven J., Potluri, Shobha, Cox, David R., Li, Qibin, Li, Yingrui, Du, Yuanping, Chen, Ruoyan, Cao, Hongzhi, Li, Ning, Cao, Sujie, Wang, Jun, Bovenberg, Jasper A., Jukema, J. Wouter, van der Harst, Pim, Sijbrands, Eric J., Hottenga, Jouke-Jan, Uitterlinden, Andre G., Swertz, Morris A., van Ommen, Gert-Jan B., de Bakker, Paul I.W., Eline Slagboom, P., Boomsma, Dorret I., Wijmenga, Cisca, van Duijn, Cornelia M.
Published 2015