PI3K/Akt/mTOR inhibitors in breast cancer

by Joycelyn JX Lee, Kiley Loh, Yoon-Sim Yap
Published 2015-12-01

Emerging systemic therapy options beyond CDK4/6 inhibitors for hormone receptor-positive HER2-negative advanced breast cancer

by Jun Ma, Jack Junjie Chan, Ching Han Toh, Yoon-Sim Yap
Published 2023-09-01

Classification of HER2-negative breast cancers by copy number alteration status reveals molecular differences associated with chromosome 17 gene aberrations

by Jui Wan Loh, Abner Herbert Lim, Jason Yongsheng Chan, Yoon-Sim Yap
Published 2023-10-01

Improving indel detection specificity of the Ion Torrent PGM benchtop sequencer.

by Zhen Xuan Yeo, Maurice Chan, Yoon Sim Yap, Peter Ang, Steve Rozen, Ann Siew Gek Lee
Published 2012-01-01

Regulatory and operational challenges in conducting Asian International Academic Trial for expanding the indications of cancer drugs

by Tomomi Hata, Kenichi Nakamura, Kan Yonemori, Emi Noguchi, Makiko Watanabe, Joohyuk Sohn, Yen‐Shen Lu, Yoon‐Sim Yap, Kenji Tamura, Yasuhiro Fujiwara
Published 2021-05-01

Potential value of ctDNA monitoring in metastatic HR + /HER2 − breast cancer: longitudinal ctDNA analysis in the phase Ib MONALEESASIA trial

by Joanne Chiu, Fei Su, Mukta Joshi, Norikazu Masuda, Takashi Ishikawa, Tomoyuki Aruga, Juan Pablo Zarate, Naveen Babbar, O. Alejandro Balbin, Yoon-Sim Yap
Published 2023-08-01

Erratum: Iyer, A., et al. Integrative Analysis and Machine Learning Based Characterization of Single Circulating Tumor Cells. <em>J. Clin. Med.</em> 2020, <em>9</em>, 1206

by Arvind Iyer, Krishan Gupta, Shreya Sharma, Kishore Hari, Yi Fang Lee, Neevan Ramalingam, Yoon Sim Yap, Jay West, Ali Asgar Bhagat, Balaram Vishnu Subramani, Burhanuddin Sabuwala, Tuan Zea Tan, Jean Paul Thiery, Mohit Kumar Jolly, Naveen Ramalingam, Debarka Sengupta
Published 2021-01-01

Integrative Analysis and Machine Learning Based Characterization of Single Circulating Tumor Cells

by Arvind Iyer, Krishan Gupta, Shreya Sharma, Kishore Hari, Yi Fang Lee, Neevan Ramalingam, Yoon Sim Yap, Jay West, Ali Asgar Bhagat, Balaram Vishnu Subramani, Burhanuddin Sabuwala, Tuan Zea Tan, Jean Paul Thiery, Mohit Kumar Jolly, Naveen Ramalingam, Debarka Sengupta
Published 2020-04-01

Clinical validation of an ultra high-throughput spiral microfluidics for the detection and enrichment of viable circulating tumor cells.

by Bee Luan Khoo, Majid Ebrahimi Warkiani, Daniel Shao-Weng Tan, Ali Asgar S Bhagat, Darryl Irwin, Dawn Pingxi Lau, Alvin S T Lim, Kiat Hon Lim, Sai Sakktee Krisna, Wan-Teck Lim, Yoon Sim Yap, Soo Chin Lee, Ross A Soo, Jongyoon Han, Chwee Teck Lim
Published 2014-01-01

Complementary Sequential Circulating Tumor Cell (CTC) and Cell-Free Tumor DNA (ctDNA) Profiling Reveals Metastatic Heterogeneity and Genomic Changes in Lung Cancer and Breast Cance...

by Say Li Kong, Xingliang Liu, Swee Jin Tan, Joyce A. Tai, Ler Yee Phua, Huay Mei Poh, Trifanny Yeo, Yong Wei Chua, Yu Xuan Haw, Wen Huan Ling, Raymond Chee Hui Ng, Raymond Chee Hui Ng, Tira J. Tan, Tira J. Tan, Kiley Wei Jen Loh, Daniel Shao-Weng Tan, Quan Sing Ng, Mei Kim Ang, Chee Keong Toh, Yi Fang Lee, Chwee Teck Lim, Tony Kiat Hon Lim, Axel M. Hillmer, Axel M. Hillmer, Axel M. Hillmer, Yoon Sim Yap, Yoon Sim Yap, Wan-Teck Lim, Wan-Teck Lim, Wan-Teck Lim
Published 2021-07-01

Predictive Factors for BRCA1 and BRCA2 Genetic Testing in an Asian Clinic-Based Population.

by Edward S Y Wong, Sandhya Shekar, Claire H T Chan, Lewis Z Hong, Suk-Yean Poon, Toomas Silla, Clarabelle Lin, Vikrant Kumar, Sonia Davila, Mathijs Voorhoeve, Aye Aye Thike, Gay Hui Ho, Yoon Sim Yap, Puay Hoon Tan, Min-Han Tan, Peter Ang, Ann S G Lee
Published 2015-01-01

Detection and prognostic relevance of circulating tumour cells (CTCs) in Asian breast cancers using a label-free microfluidic platform.

by Yoon-Sim Yap, Man Chun Leong, Yong Wei Chua, Kiley Wei Jen Loh, Guek Eng Lee, Elaine Hsuen Lim, Rebecca Dent, Raymond Chee Hui Ng, John Heng-Chi Lim, Garima Singh, Angela Tan, Guofeng Guan, Andrew Wu, Yi Fang Lee, Ali Asgar S Bhagat, Darren Wan-Teck Lim
Published 2019-01-01

Landscape of germline pathogenic variants in patients with dual primary breast and lung cancer

by Ning-Yuan Lee, Melissa Hum, Sabna Zihara, Lanying Wang, Matthew K. Myint, Darren Wan-Teck Lim, Chee-Keong Toh, Anders Skanderup, Jens Samol, Min-Han Tan, Peter Ang, Soo-Chin Lee, Eng-Huat Tan, Gillianne G. Y. Lai, Daniel S. W. Tan, Yoon-Sim Yap, Ann S. G. Lee
Published 2023-07-01

Correction: Landscape of germline pathogenic variants in patients with dual primary breast and lung cancer

by Ning-Yuan Lee, Melissa Hum, Sabna Zihara, Lanying Wang, Matthew K. Myint, Darren Wan-Teck Lim, Chee-Keong Toh, Anders Skanderup, Jens Samol, Min-Han Tan, Peter Ang, Soo-Chin Lee, Eng-Huat Tan, Gillianne G. Y. Lai, Daniel S. W. Tan, Yoon-Sim Yap, Ann S. G. Lee
Published 2023-08-01

Tissue-specific cell-free DNA degradation quantifies circulating tumor DNA burden

by Guanhua Zhu, Yu A. Guo, Danliang Ho, Polly Poon, Zhong Wee Poh, Pui Mun Wong, Anna Gan, Mei Mei Chang, Dimitrios Kleftogiannis, Yi Ting Lau, Brenda Tay, Wan Jun Lim, Clarinda Chua, Tira J. Tan, Si-Lin Koo, Dawn Q. Chong, Yoon Sim Yap, Iain Tan, Sarah Ng, Anders J. Skanderup
Published 2021-04-01

Effects of housing value and medical subsidy on treatment and outcomes of breast cancer patients in Singapore: A retrospective cohort study

by Fuh Yong Wong, Ru Xin Wong, Siqin Zhou, Whee Sze Ong, Pin Pin Pek, Yoon-Sim Yap, Benita Kiat Tee Tan, Joanne Yuen Yie Ngeow, Veronique Kiak Mien Tan, Yirong Sim, Su-Ming Tan, Swee Ho Lim, Preetha Madhukumar, Tira Jing Ying Tan, Kiley Wei-Jen Loh, Marcus Eng Hock Ong, Ting Hway Wong
Published 2021-01-01

HER2 expression, copy number variation and survival outcomes in HER2-low non-metastatic breast cancer: an international multicentre cohort study and TCGA-METABRIC analysis

by Ryan Shea Ying Cong Tan, Whee Sze Ong, Kyung-Hun Lee, Abner Herbert Lim, Seri Park, Yeon Hee Park, Ching-Hung Lin, Yen-Shen Lu, Makiko Ono, Takayuki Ueno, Yoichi Naito, Tatsuya Onishi, Geok-Hoon Lim, Su-Ming Tan, Han-Byoel Lee, Han Suk Ryu, Wonshik Han, Veronique Kiak Mien Tan, Fuh-Yong Wong, Seock-Ah Im, Puay Hoon Tan, Jason Yongsheng Chan, Yoon-Sim Yap
Published 2022-03-01

Impact of Cryotherapy on Sensory, Motor, and Autonomic Neuropathy in Breast Cancer Patients Receiving Paclitaxel: A Randomized, Controlled Trial

by Ding Quan Ng, Ding Quan Ng, Chia Jie Tan, Boon Chua Soh, Mabel May Leng Tan, Soon Yue Loh, Yam Eng Tan, Hui Hui Ong, Peggy Pei Chee Teng, Jack Junjie Chan, Wen Yee Chay, Joycelyn Lee, Gillianne Lai, Sok Yuen Beh, Tira Jing Ying Tan, Yoon Sim Yap, Guek Eng Lee, Mabel Wong, Rebecca Dent, Rebecca Dent, Yew Long Lo, Yew Long Lo, Yew Long Lo, Alexandre Chan, Alexandre Chan, Alexandre Chan, Kiley Wei-Jen Loh, Kiley Wei-Jen Loh
Published 2020-12-01