Recent advances and challenges of rare variant association analysis in the biobank sequencing era

by Wenan Chen, Brandon J. Coombes, Nicholas B. Larson
Published 2022-10-01

Study on dynamic and static elastic moduli of shale oil by different loading methods

by Huiyuan Bian, Fei Wang, Wenan Chen, Haiwen Wang
Published 2023-01-01

A Review of Single-Cell RNA-Seq Annotation, Integration, and Cell–Cell Communication

by Changde Cheng, Wenan Chen, Hongjian Jin, Xiang Chen
Published 2023-07-01

UMI-count modeling and differential expression analysis for single-cell RNA sequencing

by Wenan Chen, Yan Li, John Easton, David Finkelstein, Gang Wu, Xiang Chen
Published 2018-05-01

A rare variant analysis framework using public genotype summary counts to prioritize disease-predisposition genes

by Wenan Chen, Shuoguo Wang, Saima Sultana Tithi, David W. Ellison, Daniel J. Schaid, Gang Wu
Published 2022-05-01

A comparison of methods accounting for batch effects in differential expression analysis of UMI count based single cell RNA sequencing

by Wenan Chen, Silu Zhang, Justin Williams, Bensheng Ju, Bridget Shaner, John Easton, Gang Wu, Xiang Chen
Published 2020-01-01

Germline landscape of RPA1, RPA2 and RPA3 variants in pediatric malignancies: identification of RPA1 as a novel cancer predisposition candidate gene

by Richa Sharma, Ninad Oak, Wenan Chen, Rose Gogal, Martin Kirschner, Martin Kirschner, Fabian Beier, Fabian Beier, Michael J. Schnieders, Maria Spies, Kim E. Nichols, Marcin Wlodarski
Published 2023-10-01

Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response: Meta-analysis of three treatment cohorts.

by Joey Ward, Nicholas Graham, Rona J Strawbridge, Amy Ferguson, Gregory Jenkins, Wenan Chen, Karen Hodgson, Mark Frye, Richard Weinshilboum, Rudolf Uher, Cathryn M Lewis, Joanna Biernacka, Daniel J Smith
Published 2018-01-01

Protocol for immunophenotyping out-of-hospital cardiac arrest patients

by Kohei Yamada, Jaivardhan A. Menon, Yaunghyun Kim, Changde Cheng, Wenan Chen, Jenny A. Shih, Ana B. Villasenor-Altamirano, Xiang Chen, Tomoyoshi Tamura, Louis T. Merriam, Edy Y. Kim, Alexandra J. Weissman
Published 2024-03-01

S107: IDENTIFICATION AND CHARACTERIZATION OF GERMLINE NBN VARIANTS RELATED TO B-ALL PREDISPOSITION

by Carolin Escherich, Wenan Chen, Wenjian Yang, David T. Teachey, Elizabeth A. Raetz, Meenakshi Devidas, Gang Wu, Kim E. Nichols, Hiroto Inaba, Ching-Hon Pui, Sima Jeha, Stephen P. Hunger, Mignon L. Loh, Jun J. Yang
Published 2023-08-01

Genome-wide mapping of cancer dependency genes and genetic modifiers of chemotherapy in high-risk hepatoblastoma

by Jie Fang, Shivendra Singh, Changde Cheng, Sivaraman Natarajan, Heather Sheppard, Ahmed Abu-Zaid, Adam D. Durbin, Ha Won Lee, Qiong Wu, Jacob Steele, Jon P. Connelly, Hongjian Jin, Wenan Chen, Yiping Fan, Shondra M. Pruett-Miller, Jerold E. Rehg, Selene C. Koo, Teresa Santiago, Joseph Emmons, Stefano Cairo, Ruoning Wang, Evan S. Glazer, Andrew J. Murphy, Taosheng Chen, Andrew M. Davidoff, Carolina Armengol, John Easton, Xiang Chen, Jun Yang
Published 2023-07-01

Machine learning suggests polygenic risk for cognitive dysfunction in amyotrophic lateral sclerosis

by Katerina Placek, Michael Benatar, Joanne Wuu, Evadnie Rampersaud, Laura Hennessy, Vivianna M Van Deerlin, Murray Grossman, David J Irwin, Lauren Elman, Leo McCluskey, Colin Quinn, Volkan Granit, Jeffrey M Statland, Ted M Burns, John Ravits, Andrea Swenson, Jon Katz, Erik P Pioro, Carlayne Jackson, James Caress, Yuen So, Samuel Maiser, David Walk, Edward B Lee, John Q Trojanowski, Philip Cook, James Gee, Jin Sha, Adam C Naj, Rosa Rademakers, The CReATe Consortium, Wenan Chen, Gang Wu, J Paul Taylor, Corey T McMillan
Published 2021-01-01