The Plasmodium falciparum Rh5 invasion protein complex reveals an excess of rare variant mutations

by Leonard Ndwiga, Victor Osoti, Kevin Omondi Ochwedo, Kevin Wamae, Philip Bejon, Julian C. Rayner, George Githinji, Lynette Isabella Ochola-Oyier
Published 2021-06-01

Pyronaridine–artesunate and artemether–lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children: a randomized controlled non-inferiority tri...

by Johanna M. Roth, Patrick Sawa, Nicodemus Makio, George Omweri, Victor Osoti, Selpha Okach, Felix Choy, Henk D. F. H. Schallig, Pètra Mens
Published 2018-05-01

Comparison of home fortification with two iron formulations among Kenyan children: Rationale and design of a placebo-controlled non-inferiority trial

by Emily M. Teshome, Walter Otieno, Sofie R. Terwel, Victor Osoti, Ayşe Y. Demir, Pauline E.A. Andango, Andrew M. Prentice, Hans Verhoef
Published 2017-09-01

Daily home fortification with iron as ferrous fumarate versus NaFeEDTA: a randomised, placebo-controlled, non-inferiority trial in Kenyan children

by Emily M. Teshome, Pauline E. A. Andang’o, Victor Osoti, Sofie R. Terwel, Walter Otieno, Ayşe Y. Demir, Andrew M. Prentice, Hans Verhoef
Published 2017-04-01

Plasmodium falciparum gametocyte dynamics after pyronaridine–artesunate or artemether–lumefantrine treatment

by Johanna M. Roth, Patrick Sawa, George Omweri, Victor Osoti, Nicodemus Makio, John Bradley, Teun Bousema, Henk D. F. H. Schallig, Pètra F. Mens
Published 2018-06-01

Low frequency of Plasmodium falciparum hrp2/3 deletions from symptomatic infections at a primary healthcare facility in Kilifi, Kenya

by Dorcas Okanda, Leonard Ndwiga, Victor Osoti, Nicole Achieng, Juliana Wambua, Caroline Ngetsa, Peter Lubell-Doughtie, Anuraj Shankar, Philip Bejon, Philip Bejon, Lynette Isabella Ochola-Oyier
Published 2023-02-01

Maintenance of high temporal Plasmodium falciparum genetic diversity and complexity of infection in asymptomatic and symptomatic infections in Kilifi, Kenya from 2007 to 2018

by Kelvin M. Kimenyi, Kevin Wamae, Joyce M. Ngoi, Zaydah R. de Laurent, Leonard Ndwiga, Victor Osoti, George Obiero, Abdirahman I. Abdi, Philip Bejon, Lynette Isabella Ochola-Oyier
Published 2022-06-01

Validation of saline, PBS and a locally produced VTM at varying storage conditions to detect the SARS-CoV-2 virus by qRT-PCR

by Caroline Ngetsa, Victor Osoti, Dorcas Okanda, Faith Marura, Krupali Shah, Henry Karanja, Daisy Mugo, John Gitonga, Martin Mutunga, Clement Lewa, Benedict Orindi, Philip Bejon, Lynette Isabella Ochola-Oyier
Published 2023-01-01

Validation of saline, PBS and a locally produced VTM at varying storage conditions to detect the SARS-CoV-2 virus by qRT-PCR.

by Caroline Ngetsa, Victor Osoti, Dorcas Okanda, Faith Marura, Krupali Shah, Henry Karanja, Daisy Mugo, John Gitonga, Martin Mutunga, Clement Lewa, Benedict Orindi, Philip Bejon, Lynette Isabella Ochola-Oyier
Published 2023-01-01

The Impact of Hotspot-Targeted Interventions on Malaria Transmission in Rachuonyo South District in the Western Kenyan Highlands: A Cluster-Randomized Controlled Trial.

by Teun Bousema, Gillian Stresman, Amrish Y Baidjoe, John Bradley, Philip Knight, William Stone, Victor Osoti, Euniah Makori, Chrispin Owaga, Wycliffe Odongo, Pauline China, Shehu Shagari, Ogobara K Doumbo, Robert W Sauerwein, Simon Kariuki, Chris Drakeley, Jennifer Stevenson, Jonathan Cox
Published 2016-04-01

Targeted amplicon deep sequencing of ama1 and mdr1 to track within-host P. falciparum diversity throughout treatment in a clinical drug trial [version 3; peer review: 2 approved, 2...

by Mainga Hamaluba, Juliana Wambua, Arjen M. Dondorp, Jennifer Musyoki, Caroline Ngetsa, Oksana Kharabora, Leonard Ndwiga, Zaydah de Laurent, Kevin Wamae, Kelvin Kimenyi, Gabriel Mwambingu, Peter Kalume, Philip Bejon, Jeffrey Bailey, Rob van der Pluijm, Lynette Ochola-Oyier, Jonathan Juliano, Victor Osoti
Published 2023-10-01

Targeted amplicon deep sequencing of ama1 and mdr1 to track within-host P. falciparum diversity throughout treatment in a clinical drug trial [version 2; peer review: 2 approved, 1...

by Mainga Hamaluba, Juliana Wambua, Arjen M. Dondorp, Jennifer Musyoki, Caroline Ngetsa, Oksana Kharabora, Leonard Ndwiga, Zaydah de Laurent, Kevin Wamae, Kelvin Kimenyi, Gabriel Mwambingu, Peter Kalume, Philip Bejon, Jeffrey Bailey, Rob van der Pluijm, Lynette Ochola-Oyier, Jonathan Juliano, Victor Osoti
Published 2022-12-01

Targeted amplicon deep sequencing of ama1 and mdr1 to track within-host P. falciparum diversity throughout treatment in a clinical drug trial [version 4; peer review: 2 approved, 2...

by Mainga Hamaluba, Juliana Wambua, Arjen M. Dondorp, Jennifer Musyoki, Caroline Ngetsa, Oksana Kharabora, Leonard Ndwiga, Zaydah de Laurent, Kevin Wamae, Kelvin Kimenyi, Gabriel Mwambingu, Peter Kalume, Philip Bejon, Jeffrey Bailey, Rob van der Pluijm, Lynette Ochola-Oyier, Jonathan Juliano, Victor Osoti
Published 2024-03-01

A review of the frequencies of Plasmodium falciparum Kelch 13 artemisinin resistance mutations in Africa

by Leonard Ndwiga, Kelvin M. Kimenyi, Kevin Wamae, Victor Osoti, Mercy Akinyi, Irene Omedo, Deus S. Ishengoma, Nancy Duah-Quashie, Ben Andagalu, Anita Ghansah, Alfred Amambua-Ngwa, Stephen Tukwasibwe, Sofonias K. Tessema, Corine Karema, Abdoulaye A. Djimde, Arjen M. Dondorp, Jaishree Raman, Robert W. Snow, Philip Bejon, Lynette Isabella Ochola-Oyier
Published 2021-08-01

Pooled testing conserves SARS-CoV-2 laboratory resources and improves test turn-around time: experience on the Kenyan Coast [version 2; peer review: 3 approved]

by Charles N. Agoti, Martin Mutunga, Arnold W. Lambisia, Domtila Kimani, Robinson Cheruiyot, Patience Kiyuka, Clement Lewa, Elijah Gicheru, Metrine Tendwa, Khadija Said Mohammed, Victor Osoti, Johnstone Makale, Brian Tawa, Calleb Odundo, Wesley Cheruiyot, Wilfred Nyamu, Wilson Gumbi, Jedidah Mwacharo, Lydia Nyamako, Edward Otieno, David Amadi, Janet Thoya, Angela Karani, Daisy Mugo, Jennifer Musyoki, Horace Gumba, Salim Mwarumba, Bonface M. Gichuki, Susan Njuguna, Debra Riako, Shadrack Mutua, John N. Gitonga, Yiakon Sein, Brian Bartilol, Shaban J. Mwangi, Donwilliams O. Omuoyo, John M. Morobe, Zaydah R. de Laurent, Philip Bejon, Lynette Isabella Ochola-Oyier, Benjamin Tsofa
Published 2021-02-01

Pooled testing conserves SARS-CoV-2 laboratory resources and improves test turn-around time: experience on the Kenyan Coast [version 1; peer review: 3 approved]

by Charles N. Agoti, Martin Mutunga, Arnold W. Lambisia, Domtila Kimani, Robinson Cheruiyot, Patience Kiyuka, Clement Lewa, Elijah Gicheru, Metrine Tendwa, Khadija Said Mohammed, Victor Osoti, Johnstone Makale, Brian Tawa, Calleb Odundo, Wesley Cheruiyot, Wilfred Nyamu, Wilson Gumbi, Jedidah Mwacharo, Lydia Nyamako, Edward Otieno, David Amadi, Janet Thoya, Angela Karani, Daisy Mugo, Jennifer Musyoki, Horace Gumba, Salim Mwarumba, Bonface M. Gichuki, Susan Njuguna, Debra Riako, Shadrack Mutua, John N. Gitonga, Yiakon Sein, Brian Bartilol, Shaban J. Mwangi, Donwilliams O. Omuoyo, John M. Morobe, Zaydah R. de Laurent, Philip Bejon, Lynette Isabella Ochola-Oyier, Benjamin Tsofa
Published 2020-08-01

An optimization of four SARS-CoV-2 qRT-PCR assays in a Kenyan laboratory to support the national COVID-19 rapid response teams [version 2; peer review: 2 approved]

by Shadrack Mutua, Brian Bartilol, Shaban J. Mwangi, Debra Riako, Lydia Nyamako, Bonface M. Gichuki, Henry Karanja, Angela Karani, John N. Gitonga, Daisy Mugo, Brian Tawa, Wilson Gumbi, Wesley Cheruiyot, Metrine Tendwa, John K. Nyambu, Yiakon Sein, Thani Suleiman Thani, Shem O. Patta, Benson Kitole, Eric K. Maitha, Barke S. Muslih, Mohamed S. Mwakinangu, Philip Bejon, Benjamin Tsofa, Joyce U. Nyiro, John Ochieng Otieno, Leonard Ndwiga, Patience Kiyuka, Johnstone Makale, Kevin Wamae, Victor Osoti, John Mwita Morobe, Calleb Odundo, Arnold W. Lambisia, Martin Mutunga, Salim Mwarumba, Lynette Isabella Ochola-Oyier, Charles N. Agoti, Clement Lewa, Elijah Gicheru, Jennifer Musyoki, Susan Njuguna, Horace Gumba, Domtila Kimani, Jedidah Mwacharo, Zaydah R. de Laurent, Khadija Said Mohammed, Robinson Cheruiyot, Donwilliams O. Omuoyo
Published 2022-03-01

Maintaining laboratory quality assurance and safety in a pandemic: Experiences from the KEMRI-Wellcome Trust Research Programme laboratory’s COVID-19 response [version 2; peer revi...

by Shadrack Mutua, Brian Bartilol, Debra Riako, Lydia Nyamako, Angela Karani, Daisy Mugo, Brian Tawa, Michael Opiyo, Wesley Cheruiyot, Metrine Tendwa, Oscar Kai, Caroline Ngetsa, Yiakon Sein, Nelson Ouma, Arnold W. Lambisia, Bonface M. Gichuki, Boniface Karia, John M. Morobe, Shaban Mwangi, Benjamin Tsofa, Philip Bejon, Alfred Mwakubia, Fredrick Mitsanze, Kelly Ominde, Patience Kiyuka, Martin Rono, Johnstone Makale, Agnes Mutiso, Perpetual Wanjiku, Victor Osoti, John N. Gitonga, Alfred Mwanzu, Calleb Odundo, Martin Mutunga, Salim Mwarumba, Donwilliams O. Omuoyo, Amek Nyaguara, Clement Lewa, Elijah Gicheru, Wilson Gumbi, Jennifer Musyoki, Susan Njuguna, Moses Mosobo, Lynette Isabella Ochola-Oyier, Horace Gumba, Wilfred Nyamu, Khadija Said Mohammed, Janet Thoya, Edward Otieno, Domtila Kimani, Jedidah Mwacharo, David Amadi, Charles N. Agoti, Zaydah R. de Laurent, Robinson Cheruiyot
Published 2022-03-01