Antisense-Mediated Down-Regulation of Factor V-Short Splicing in a Liver Cell Line Model

by Alice M. Todaro, Tilman M. Hackeng, Elisabetta Castoldi
Published 2021-10-01

Platelet full length TFPI-α in healthy volunteers is not affected by sex or hormonal use.

by Kristien Winckers, Stella Thomassen, Hugo Ten Cate, Tilman M Hackeng
Published 2017-01-01

Differential Effects of Platelet Factor 4 (CXCL4) and Its Non-Allelic Variant (CXCL4L1) on Cultured Human Vascular Smooth Muscle Cells

by Dawid M. Kaczor, Rafael Kramann, Tilman M. Hackeng, Leon J. Schurgers, Rory R. Koenen
Published 2022-01-01

Vitamin K and Hallmarks of Ageing: Focus on Diet and Gut Microbiome

by Lu Dai, Denise Mafra, Paul G. Shiels, Tilman M. Hackeng, Peter Stenvinkel, Leon J. Schurgers
Published 2023-06-01

Exogenous Integrin αIIbβ3 Inhibitors Revisited: Past, Present and Future Applications

by Danique L. van den Kerkhof, Paola E.J. van der Meijden, Tilman M. Hackeng, Ingrid Dijkgraaf
Published 2021-03-01

New Trends, Advantages and Disadvantages in Anticoagulation and Coating Methods Used in Extracorporeal Life Support Devices

by Anne Willers, Jutta Arens, Silvia Mariani, Helena Pels, Jos G. Maessen, Tilman M. Hackeng, Roberto Lorusso, Justyna Swol
Published 2021-08-01

Similar hypercoagulable state and thrombosis risk in type I and type III protein S-deficient individuals from families with mixed type I/III protein S deficiency

by Elisabetta Castoldi, Lisbeth F.A. Maurissen, Daniela Tormene, Luca Spiezia, Sabrina Gavasso, Claudia Radu, Tilman M. Hackeng, Jan Rosing, Paolo Simioni
Published 2010-09-01

Inhibition of platelet adhesion, thrombus formation, and fibrin formation by a potent αIIbβ3 integrin inhibitor from ticks

by Danique L. van denKerkhof, Magdolna Nagy, Kanin Wichapong, Sanne L.N. Brouns, Johan W. M. Heemskerk, Tilman M. Hackeng, Ingrid Dijkgraaf
Published 2021-01-01

Stimuli of sensory-motor nerves terminate arterial contractile effects of endothelin-1 by CGRP and dissociation of ET-1/ET(A)-receptor complexes.

by Merlijn J P M T Meens, Matthijs G Compeer, Tilman M Hackeng, Marc A van Zandvoort, Ben J A Janssen, Jo G R De Mey
Published 2010-01-01

Thiol-ene conjugation of a VEGF peptide to electrospun scaffolds for potential applications in angiogenesis

by Tianyu Yao, Honglin Chen, Rong Wang, Rebeca Rivero, Fengyu Wang, Lilian Kessels, Stijn M. Agten, Tilman M. Hackeng, Tim G.A.M. Wolfs, Daidi Fan, Matthew B. Baker, Lorenzo Moroni
Published 2023-02-01

Molecular Detection of Venous Thrombosis in Mouse Models Using SPECT/CT

by Annemiek Dickhout, Pieter Van de Vijver, Nicole Bitsch, Stefan J. van Hoof, Stella L. G. D. Thomassen, Steffen Massberg, Peter Timmerman, Frank Verhaegen, Rory R. Koenen, Ingrid Dijkgraaf, Tilman M. Hackeng
Published 2022-06-01

Extracellular vimentin mimics VEGF and is a target for anti-angiogenic immunotherapy

by Judy R. van Beijnum, Elisabeth J. M. Huijbers, Karlijn van Loon, Athanasios Blanas, Parvin Akbari, Arno Roos, Tse J. Wong, Stepan S. Denisov, Tilman M. Hackeng, Connie R. Jimenez, Patrycja Nowak-Sliwinska, Arjan W. Griffioen
Published 2022-05-01

Vaccination with a bacterial peptide conjugated to SARS-CoV-2 receptor-binding domain accelerates immunity and protects against COVID-19

by Athanasios Blanas, Haiko Karsjens, Aafke de Ligt, Elisabeth J.M. Huijbers, Karlijn van Loon, Stepan S. Denisov, Canan Durukan, Diederik J.M. Engbersen, Jan Groen, Sven Hennig, Tilman M. Hackeng, Judy R. van Beijnum, Arjan W. Griffioen
Published 2022-08-01

Mass spectrometry imaging of L-[ring-13C6]-labeled phenylalanine and tyrosine kinetics in non-small cell lung carcinoma

by Jianhua Cao, Benjamin Balluff, Martijn Arts, Ludwig J. Dubois, Luc J. C. van Loon, Tilman M. Hackeng, Hans M. H. van Eijk, Gert Eijkel, Lara R. Heij, Zita Soons, Steven W. M. Olde Damink, Ron M. A. Heeren
Published 2021-06-01

Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear

by Johana Hrdinova, Delia I. Fernández, Bogac Ercig, Bibian M. E. Tullemans, Dennis P. L. Suylen, Stijn M. Agten, Kerstin Jurk, Tilman M. Hackeng, Karen Vanhoorelbeke, Jan Voorberg, Chris P. M. Reutelingsperger, Kanin Wichapong, Johan W. M. Heemskerk, Gerry A. F. Nicolaes
Published 2022-02-01

Genetic and pharmacological modifications of thrombin formation in apolipoprotein e-deficient mice determine atherosclerosis severity and atherothrombosis onset in a neutrophil-dep...

by Julian I Borissoff, Jeroen J T Otten, Sylvia Heeneman, Peter Leenders, René van Oerle, Oliver Soehnlein, Sarah T B G Loubele, Karly Hamulyák, Tilman M Hackeng, Mat J A P Daemen, Jay L Degen, Hartmut Weiler, Charles T Esmon, Joanne van Ryn, Erik A L Biessen, Henri M H Spronk, Hugo ten Cate
Published 2013-01-01

Serial thrombin generation and exploration of alternative anticoagulants in critically ill COVID-19 patients: Observations from Maastricht Intensive Care COVID Cohort

by Tom W. van de Berg, Tom W. van de Berg, Mark M. G. Mulder, Teba Alnima, Magdolna Nagy, Magdolna Nagy, Rene van Oerle, Rene van Oerle, Erik A. M. Beckers, Erik A. M. Beckers, Tilman M. Hackeng, Tilman M. Hackeng, Anne-Marije Hulshof, Jan-Willem E. M. Sels, Jan-Willem E. M. Sels, Yvonne M. C. Henskens, Yvonne M. C. Henskens, Iwan C. C. van der Horst, Iwan C. C. van der Horst, Hugo ten Cate, Hugo ten Cate, Hugo ten Cate, Henri M. H. Spronk, Henri M. H. Spronk, Henri M. H. Spronk, Bas C. T. van Bussel, Bas C. T. van Bussel, MaastrICCht Collaborators
Published 2022-10-01

Coated platelets function in platelet-dependent fibrin formation via integrin αIIbβ3 and transglutaminase factor XIII

by Nadine J.A. Mattheij, Frauke Swieringa, Tom G. Mastenbroek, Michelle A. Berny-Lang, Frauke May, Constance C.F.M.J. Baaten, Paola E.J. van der Meijden, Yvonne M.C. Henskens, Erik A.M. Beckers, Dennis P.L. Suylen, Marc W. Nolte, Tilman M. Hackeng, Owen J.T. McCarty, Johan W.M. Heemskerk, Judith M.E.M. Cosemans
Published 2016-04-01