Chorioamnionitis Causes Kidney Inflammation, Podocyte Damage, and Pro-fibrotic Changes in Fetal Lambs

by Lieke A. Hoogenboom, Lieke A. Hoogenboom, A. Titia Lely, Matthew W. Kemp, Matthew W. Kemp, Matthew W. Kemp, Matthew W. Kemp, Masatoshi Saito, Alan H. Jobe, Tim G. A. M. Wolfs, Tim G. A. M. Wolfs, Michiel F. Schreuder
Published 2022-04-01

Enteral Feeding Interventions in the Prevention of Necrotizing Enterocolitis: A Systematic Review of Experimental and Clinical Studies

by Ilse H. de Lange, Charlotte van Gorp, Laurens D. Eeftinck Schattenkerk, Wim G. van Gemert, Joep P. M. Derikx, Tim G. A. M. Wolfs
Published 2021-05-01

Screening of Chorioamnionitis Using Volatile Organic Compound Detection in Exhaled Breath: A Pre-clinical Proof of Concept Study

by Daan R. M. G. Ophelders, Daan R. M. G. Ophelders, Agnes W. Boots, Agnes W. Boots, Matthias C. Hütten, Salwan Al-Nasiry, Salwan Al-Nasiry, Reint K. Jellema, Owen B. Spiller, Frederik-Jan van Schooten, Frederik-Jan van Schooten, Agnieszka Smolinska, Agnieszka Smolinska, Tim G. A. M. Wolfs, Tim G. A. M. Wolfs
Published 2021-05-01

Prenatal administration of multipotent adult progenitor cells modulates the systemic and cerebral immune response in an ovine model of chorioamnionitis

by Luise Klein, Daan R.M.G. Ophelders, Daniel van den Hove, Maurits Damoiseaux, Bart P.F. Rutten, Chris P.M. Reutelingsperger, Leon J. Schurgers, Tim G.A.M. Wolfs
Published 2022-08-01

Global Hypoxia-Ischemia Induced Inflammation and Structural Changes in the Preterm Ovine Gut Which Were Not Ameliorated by Mesenchymal Stem Cell Treatment

by Maria Nikiforou, Carolin Willburger, Anja E de Jong, Nico Kloosterboer, Reint K Jellema, Daan R M G Ophelders, Harry W M Steinbusch, Boris W Kramer, Tim G A M Wolfs
Published 2016-04-01

Thiol-ene conjugation of a VEGF peptide to electrospun scaffolds for potential applications in angiogenesis

by Tianyu Yao, Honglin Chen, Rong Wang, Rebeca Rivero, Fengyu Wang, Lilian Kessels, Stijn M. Agten, Tilman M. Hackeng, Tim G.A.M. Wolfs, Daidi Fan, Matthew B. Baker, Lorenzo Moroni
Published 2023-02-01

Annexin A1 as Neuroprotective Determinant for Blood-Brain Barrier Integrity in Neonatal Hypoxic-Ischemic Encephalopathy

by Ruth Gussenhoven, Luise Klein, Daan R. M. G. Ophelders, Denise H. J. Habets, Bernd Giebel, Boris W. Kramer, Leon J. Schurgers, Chris P. M. Reutelingsperger, Tim G. A. M. Wolfs
Published 2019-01-01

Umbilical cord-mesenchymal stem cells induce a memory phenotype in CD4+ T cells

by Ezgi Sengun, Tim G. A. M. Wolfs, Valéry L. E. van Bruggen, Bram van Cranenbroek, Elles R. Simonetti, Daan Ophelders, Marien I. de Jonge, Irma Joosten, Renate G. van der Molen
Published 2023-06-01

Preterm Brain Injury, Antenatal Triggers, and Therapeutics: Timing Is Key

by Daan R.M.G. Ophelders, Ruth Gussenhoven, Luise Klein, Reint K. Jellema, Rob J.J. Westerlaken, Matthias C. Hütten, Jeroen Vermeulen, Guido Wassink, Alistair J. Gunn, Tim G.A.M. Wolfs
Published 2020-08-01

Mesenchymal Stromal Cell‐Derived Extracellular Vesicles Protect the Fetal Brain After Hypoxia‐Ischemia

by Daan R.M.G. Ophelders, Tim G.A.M. Wolfs, Reint K. Jellema, Alex Zwanenburg, Peter Andriessen, Tammo Delhaas, Anna-Kristin Ludwig, Stefan Radtke, Vera Peters, Leon Janssen, Bernd Giebel, Boris W. Kramer
Published 2016-06-01

Endotoxin induced chorioamnionitis prevents intestinal development during gestation in fetal sheep.

by Tim G A M Wolfs, Wim A Buurman, Bea Zoer, Rob M J Moonen, Joep P M Derikx, Geertje Thuijls, Eduardo Villamor, Markus Gantert, Yves Garnier, Luc J I Zimmermann, Boris W Kramer
Published 2009-01-01

Time Dependent Changes in the Ovine Neurovascular Unit; A Potential Neuroprotective Role of Annexin A1 in Neonatal Hypoxic-Ischemic Encephalopathy

by Hyun Young Park, Valéry L. E. van Bruggen, Carine J. Peutz-Kootstra, Daan R. M. G. Ophelders, Reint K. Jellema, Chris P. M. Reutelingsperger, Bart P. F. Rutten, Tim G. A. M. Wolfs
Published 2023-03-01

ST waveform analysis for monitoring hypoxic distress in fetal sheep after prolonged umbilical cord occlusion.

by Peter Andriessen, Alex Zwanenburg, Judith O E H van Laar, Rik Vullings, Ben J M Hermans, Hendrik J Niemarkt, Reint K Jellema, Daan R M G Ophelders, Tim G A M Wolfs, Boris W Kramer, Tammo Delhaas
Published 2018-01-01

IL-1α mediated chorioamnionitis induces depletion of FoxP3+ cells and ileal inflammation in the ovine fetal gut.

by Tim G A M Wolfs, Suhas G Kallapur, Graeme R Polglase, J Jane Pillow, Ilias Nitsos, John P Newnham, Claire A Chougnet, Elke Kroon, Julia Spierings, Coen H M P Willems, Alan H Jobe, Boris W Kramer
Published 2011-03-01

Hypoxia-Driven Changes in a Human Intestinal Organoid Model and the Protective Effects of Hydrolyzed Whey

by Ilse H. de Lange, Charlotte van Gorp, Kimberly R. I. Massy, Lilian Kessels, Nico Kloosterboer, Ann Bjørnshave, Marie Stampe Ostenfeld, Jan G. M. C. Damoiseaux, Joep P. M. Derikx, Wim G. van Gemert, Tim G. A. M. Wolfs
Published 2023-01-01

Chorioamnionitis induces hepatic inflammation and time-dependent changes of the enterohepatic circulation in the ovine fetus

by Cathelijne Heymans, Marcel den Dulk, Kaatje Lenaerts, Lara R. Heij, Ilse H. de Lange, Mhamed Hadfoune, Chantal van Heugten, Boris W. Kramer, Alan H. Jobe, Masatoshi Saito, Matthew W. Kemp, Tim G. A. M. Wolfs, Wim G. van Gemert
Published 2021-05-01

Chorioamnionitis, neuroinflammation, and injury: timing is key in the preterm ovine fetus

by Ruth Gussenhoven, Rob J. J. Westerlaken, Daan R. M. G. Ophelders, Alan H. Jobe, Matthew W. Kemp, Suhas G. Kallapur, Luc J. Zimmermann, Per T. Sangild, Stanislava Pankratova, Pierre Gressens, Boris W. Kramer, Bobbi Fleiss, Tim G. A. M. Wolfs
Published 2018-04-01

Mesenchymal stem cells induce T-cell tolerance and protect the preterm brain after global hypoxia-ischemia.

by Reint K Jellema, Tim G A M Wolfs, Valéria Lima Passos, Alex Zwanenburg, Daan R M G Ophelders, Elke Kuypers, Anton H N Hopman, Jeroen Dudink, Harry W Steinbusch, Peter Andriessen, Wilfred T V Germeraad, Joris Vanderlocht, Boris W Kramer
Published 2013-01-01

Ovine fetal thymus response to lipopolysaccharide-induced chorioamnionitis and antenatal corticosteroids.

by Elke Kuypers, Jennifer J P Collins, Reint K Jellema, Tim G A M Wolfs, Matthew W Kemp, Ilias Nitsos, J Jane Pillow, Graeme R Polglase, John P Newnham, Wilfred T V Germeraad, Suhas G Kallapur, Alan H Jobe, Boris W Kramer
Published 2012-01-01

Pulmonary vascular changes in extremely preterm sheep after intra-amniotic exposure to Ureaplasma parvum and lipopolysaccharide.

by Monique G M Willems, Matthew W Kemp, Laura A Fast, Nick M M Wagemaker, Leon E W Janssen, John P Newnham, Matt S Payne, Owen B Spiller, Suhas G Kallapur, Alan H Jobe, Tammo Delhaas, Boris W Kramer, Tim G A M Wolfs
Published 2017-01-01