FGFR2 protein expression in breast cancer: nuclear localisation and correlation with patient genotype

by Thompson Alastair M, Purdie Colin A, Quinlan Philip R, Baker Lee, Palmer Colin N, Ashfield Alison M, Grant Andrew, Martin Amy J, Jordan Lee B, Berg Jonathan N
Published 2011-03-01

MDM2 SNP309 is associated with high grade node positive breast tumours and is in linkage disequilibrium with a novel MDM2 intron 1 polymorphism

by Ali Clinton W, Ashfield Alison, Cassidy Andrew, McGregor Gillian, O'Neill Mary, Paulin Fiona EM, Munro Alastair J, Baker Lee, Purdie Colin A, Lane David P, Thompson Alastair M
Published 2008-10-01

Histological evaluation of AMPK signalling in primary breast cancer

by Purdie Colin A, Jordan Lee B, Kellock David, Thomson George, Bray Susan E, Robertson Katherine E, Quinlan Philip R, Baker Lee, Hadad Sirwan M, Hardie David G, Fleming Stewart, Thompson Alastair M
Published 2009-09-01

Ductal carcinoma in situ: to treat or not to treat, that is the question

by van Seijen, Maartje, Lips, Esther H., Thompson, Alastair M., Nik-Zainal, Serena, Futreal, Andrew, Hwang, E. Shelley, Verschuur, Ellen, Lane, Joanna, Jonkers, Jos, Rea, Daniel W., Wesseling, Jelle
Published 2020

Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin

by Lord, Simon R., Collins, Jennifer M., Cheng, Wei-Chen, Haider, Syed, Wigfield, Simon, Gaude, Edoardo, Fielding, Barbara A., Pinnick, Katherine E., Harjes, Ulrike, Segaran, Ashvina, Jha, Pooja, Hoefler, Gerald, Pollak, Michael N., Thompson, Alastair M., Roy, Pankaj G., English, Ruth., Adams, Rosie F., Frezza, Christian, Buffa, Francesca M., Karpe, Fredrik, Harris, Adrian L.
Published 2020

Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer.

by Lord, Simon R, Cheng, Wei-Chen, Liu, Dan, Gaude, Edoardo, Haider, Syed, Metcalf, Tom, Patel, Neel, Teoh, Eugene J, Gleeson, Fergus, Bradley, Kevin, Wigfield, Simon, Zois, Christos, McGowan, Daniel R, Ah-See, Mei-Lin, Thompson, Alastair M, Sharma, Anand, Bidaut, Luc, Pollak, Michael, Roy, Pankaj G, Karpe, Fredrik, James, Tim, English, Ruth, Adams, Rosie F, Campo, Leticia, Ayers, Lisa, Snell, Cameron, Roxanis, Ioannis, Frezza, Christian, Fenwick, John D, Buffa, Francesca M, Harris, Adrian L
Published 2018

The topography of mutational processes in breast cancer genomes.

by Morganella, Sandro, Alexandrov, Ludmil B, Glodzik, Dominik, Zou, Xueqing, Davies, Helen, Staaf, Johan, Sieuwerts, Anieta M, Brinkman, Arie B, Martin, Sancha, Ramakrishna, Manasa, Butler, Adam, Kim, Hyung-Yong, Borg, Åke, Sotiriou, Christos, Futreal, P Andrew, Campbell, Peter J, Span, Paul N, Van Laere, Steven, Lakhani, Sunil R, Eyfjord, Jorunn E, Thompson, Alastair M, Stunnenberg, Hendrik G, van de Vijver, Marc J, Martens, John WM, Børresen-Dale, Anne-Lise, Richardson, Andrea L, Kong, Gu, Thomas, Gilles, Sale, Julian, Rada, Cristina, Stratton, Michael R, Birney, Ewan, Nik-Zainal, Serena
Published 2018

Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin.

by Lord, Simon R, Collins, Jennifer M, Cheng, Wei-Chen, Haider, Syed, Wigfield, Simon, Gaude, Edoardo, Fielding, Barbara A, Pinnick, Katherine E, Harjes, Ulrike, Segaran, Ashvina, Jha, Pooja, Hoefler, Gerald, Pollak, Michael N, Thompson, Alastair M, Roy, Pankaj G, English, Ruth, Adams, Rosie F, Frezza, Christian, Buffa, Francesca M, Karpe, Fredrik, Harris, Adrian L
Published 2020

Unresected screen-detected ductal carcinoma in situ: Outcomes of 311 women in the Forget-Me-Not 2 study.

by Maxwell, Anthony J, Hilton, Bridget, Clements, Karen, Dodwell, David, Dulson-Cox, Joanne, Kearins, Olive, Kirwan, Cliona, Litherland, Janet, Mylvaganam, Senthurun, Provenzano, Elena, Pinder, Sarah E, Sawyer, Elinor, Shaaban, Abeer M, Sharma, Nisha, Stobart, Hilary, Wallis, Matthew G, Thompson, Alastair M
Published 2022

Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer.

by Lips, Esther H, Kumar, Tapsi, Megalios, Anargyros, Visser, Lindy L, Sheinman, Michael, Fortunato, Angelo, Shah, Vandna, Hoogstraat, Marlous, Sei, Emi, Mallo, Diego, Roman-Escorza, Maria, Ahmed, Ahmed A, Xu, Mingchu, van den Belt-Dusebout, Alexandra W, Brugman, Wim, Casasent, Anna K, Clements, Karen, Davies, Helen R, Fu, Liping, Grigoriadis, Anita, Hardman, Timothy M, King, Lorraine M, Krete, Marielle, Kristel, Petra, de Maaker, Michiel, Maley, Carlo C, Marks, Jeffrey R, Menegaz, Brian A, Mulder, Lennart, Nieboer, Frank, Nowinski, Salpie, Pinder, Sarah, Quist, Jelmar, Salinas-Souza, Carolina, Schaapveld, Michael, Schmidt, Marjanka K, Shaaban, Abeer M, Shami, Rana, Sridharan, Mathini, Zhang, John, Stobart, Hilary, Collyar, Deborah, Nik-Zainal, Serena, Wessels, Lodewyk FA, Hwang, E Shelley, Navin, Nicholas E, Futreal, P Andrew, Grand Challenge PRECISION consortium, Thompson, Alastair M, Wesseling, Jelle, Sawyer, Elinor J
Published 2022

Risk factors for the development of invasive cancer in unresected ductal carcinoma in situ.

by Maxwell, Anthony J, Clements, Karen, Hilton, Bridget, Dodwell, David J, Evans, Andrew, Kearins, Olive, Pinder, Sarah E, Thomas, Jeremy, Wallis, Matthew G, Thompson, Alastair M, Sloane Project Steering Group
Published 2019

Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration.

by Smid, Marcel, Rodríguez-González, F Germán, Sieuwerts, Anieta M, Salgado, Roberto, Prager-Van der Smissen, Wendy JC, Vlugt-Daane, Michelle van der, van Galen, Anne, Nik-Zainal, Serena, Staaf, Johan, Brinkman, Arie B, van de Vijver, Marc J, Richardson, Andrea L, Fatima, Aquila, Berentsen, Kim, Butler, Adam, Martin, Sancha, Davies, Helen R, Debets, Reno, Gelder, Marion E Meijer-Van, van Deurzen, Carolien HM, MacGrogan, Gaëtan, Van den Eynden, Gert GGM, Purdie, Colin, Thompson, Alastair M, Caldas, Carlos, Span, Paul N, Simpson, Peter T, Lakhani, Sunil R, Van Laere, Steven, Desmedt, Christine, Ringnér, Markus, Tommasi, Stefania, Eyford, Jorunn, Broeks, Annegien, Vincent-Salomon, Anne, Futreal, P Andrew, Knappskog, Stian, King, Tari, Thomas, Gilles, Viari, Alain, Langerød, Anita, Børresen-Dale, Anne-Lise, Birney, Ewan, Stunnenberg, Hendrik G, Stratton, Mike, Foekens, John A, Martens, John WM
Published 2018

Pre-operative stromal stiffness measured by shear wave elastography is independently associated with breast cancer-specific survival.

by Evans, Andy, Sim, Yee Ting, Pourreyron, Celine, Thompson, Alastair, Jordan, Lee, Fleming, Dawn, Purdie, Colin, Macaskill, Jane, Vinnicombe, Sarah, Pharoah, Paul
Published 2018

Survival and disease characteristics of de novo versus recurrent metastatic breast cancer in a cohort of young patients

by McKenzie, Hayley S., Maishman, Tom, Simmonds, Peter, Durcan, Lorraine, Eccles, Diana, Copson, Ellen, Altman, Douglas G., Jones, Louise, Evans, Gareth, Thompson, Alastair M., Pharaoh, Paul, Hanby, Andrew, Lakhani, Sunil, Eeles, Ros, Gilbert, Fiona J., Hamed, Hisham, Hodgson, Shirley
Published 2021

Pathological features of 11,337 patients with primary ductal carcinoma in situ (DCIS) and subsequent events: results from the UK Sloane Project.

by Shaaban, Abeer M, Hilton, Bridget, Clements, Karen, Provenzano, Elena, Cheung, Shan, Wallis, Matthew G, Sawyer, Elinor, Thomas, Jeremy S, Hanby, Andrew M, Pinder, Sarah E, Thompson, Alastair M, Sloane Project Steering Committee
Published 2021

Somatic mutations reveal asymmetric cellular dynamics in the early human embryo.

by Ju, Young Seok, Martincorena, Inigo, Gerstung, Moritz, Petljak, Mia, Alexandrov, Ludmil B, Rahbari, Raheleh, Wedge, David C, Davies, Helen R, Ramakrishna, Manasa, Fullam, Anthony, Martin, Sancha, Alder, Christopher, Patel, Nikita, Gamble, Steve, O'Meara, Sarah, Giri, Dilip D, Sauer, Torril, Pinder, Sarah E, Purdie, Colin A, Borg, Åke, Stunnenberg, Henk, van de Vijver, Marc, Tan, Benita KT, Caldas, Carlos, Tutt, Andrew, Ueno, Naoto T, van 't Veer, Laura J, Martens, John WM, Sotiriou, Christos, Knappskog, Stian, Span, Paul N, Lakhani, Sunil R, Eyfjörd, Jórunn Erla, Børresen-Dale, Anne-Lise, Richardson, Andrea, Thompson, Alastair M, Viari, Alain, Hurles, Matthew E, Nik-Zainal, Serena, Campbell, Peter J, Stratton, Michael R
Published 2017

Breast screening atypia and subsequent development of cancer: protocol for an observational analysis of the Sloane database in England (Sloane atypia cohort study).

by Jenkinson, David, Freeman, Karoline, Clements, Karen, Hilton, Bridget, Dulson-Cox, Joanne, Kearins, Olive, Stallard, Nigel, Wallis, Matthew G, Sharma, Nisha, Kirwan, Cliona, Pinder, Sarah, Provenzano, Elena, Shaaban, Abeer M, Stobart, Hilary, McDonnell, Samantha, Thompson, Alastair M, Taylor-Phillips, Sian
Published 2022

Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer.

by Lips, Esther H, Kumar, Tapsi, Megalios, Anargyros, Visser, Lindy L, Sheinman, Michael, Fortunato, Angelo, Shah, Vandna, Hoogstraat, Marlous, Sei, Emi, Mallo, Diego, Roman-Escorza, Maria, Ahmed, Ahmed A, Xu, Mingchu, van den Belt-Dusebout, Alexandra W, Brugman, Wim, Casasent, Anna K, Clements, Karen, Davies, Helen R, Fu, Liping, Grigoriadis, Anita, Hardman, Timothy M, King, Lorraine M, Krete, Marielle, Kristel, Petra, de Maaker, Michiel, Maley, Carlo C, Marks, Jeffrey R, Menegaz, Brian A, Mulder, Lennart, Nieboer, Frank, Nowinski, Salpie, Pinder, Sarah, Quist, Jelmar, Salinas-Souza, Carolina, Schaapveld, Michael, Schmidt, Marjanka K, Shaaban, Abeer M, Shami, Rana, Sridharan, Mathini, Zhang, John, Stobart, Hilary, Collyar, Deborah, Nik-Zainal, Serena, Wessels, Lodewyk FA, Hwang, E Shelley, Navin, Nicholas E, Futreal, P Andrew, Grand Challenge PRECISION consortium, Thompson, Alastair M, Wesseling, Jelle, Sawyer, Elinor J
Published 2022

Somatic mutations reveal asymmetric cellular dynamics in the early human embryo.

by Ju, Young Seok, Martincorena, Inigo, Gerstung, Moritz, Petljak, Mia, Alexandrov, Ludmil B, Rahbari, Raheleh, Wedge, David C, Davies, Helen R, Ramakrishna, Manasa, Fullam, Anthony, Martin, Sancha, Alder, Christopher, Patel, Nikita, Gamble, Steve, O'Meara, Sarah, Giri, Dilip D, Sauer, Torril, Pinder, Sarah E, Purdie, Colin A, Borg, Åke, Stunnenberg, Henk, van de Vijver, Marc, Tan, Benita KT, Caldas, Carlos, Tutt, Andrew, Ueno, Naoto T, van 't Veer, Laura J, Martens, John WM, Sotiriou, Christos, Knappskog, Stian, Span, Paul N, Lakhani, Sunil R, Eyfjörd, Jórunn Erla, Børresen-Dale, Anne-Lise, Richardson, Andrea, Thompson, Alastair M, Viari, Alain, Hurles, Matthew E, Nik-Zainal, Serena, Campbell, Peter J, Stratton, Michael R
Published 2019