Cancer Cells Upregulate Tau to Gain Resistance to DNA Damaging Agents

by Thomas Rico, Marine Denechaud, Raphaelle Caillierez, Thomas Comptdaer, Eric Adriaenssens, Luc Buée, Bruno Lefebvre
Published 2022-12-01

Tau Stabilizes Chromatin Compaction

by Thomas Rico, Melissa Gilles, Alban Chauderlier, Thomas Comptdaer, Romain Magnez, Maggy Chwastyniak, Herve Drobecq, Florence Pinet, Xavier Thuru, Luc Buée, Marie-Christine Galas, Bruno Lefebvre
Published 2021-10-01

Feeding High-Fat Diet Accelerates Development of Peripheral and Central Insulin Resistance and Inflammation and Worsens AD-like Pathology in APP/PS1 Mice

by Anna Mengr, Veronika Strnadová, Štěpán Strnad, Vladimír Vrkoslav, Helena Pelantová, Marek Kuzma, Thomas Comptdaer, Blanka Železná, Jaroslav Kuneš, Marie-Christine Galas, Andrea Pačesová, Lenka Maletínská
Published 2023-08-01

RNA-binding disturbances as a continuum from spinocerebellar ataxia type 2 to Parkinson disease

by Aurore Nkiliza, Eugénie Mutez, Clémence Simonin, Frédéric Leprêtre, Aurélie Duflot, Martin Figeac, Céline Villenet, Pierre Semaille, Thomas Comptdaer, Alexandre Genet, Bernard Sablonnière, David Devos, Luc Defebvre, Alain Destée, Marie-Christine Chartier-Harlin
Published 2016-12-01

Involvement of the immune system, endocytosis and EIF2 signaling in both genetically determined and sporadic forms of Parkinson's disease

by Eugénie Mutez, Aurore Nkiliza, Karim Belarbi, Amélie de Broucker, Christel Vanbesien-Mailliot, Séverine Bleuse, Aurélie Duflot, Thomas Comptdaer, Pierre Semaille, Renaud Blervaque, David Hot, Frederic Leprêtre, Martin Figeac, Alain Destée, Marie-Christine Chartier-Harlin
Published 2014-03-01

Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta resp...

by Caroline Manet, Zeyni Mansuroglu, Laurine Conquet, Violaine Bortolin, Thomas Comptdaer, Helena Segrt, Marie Bourdon, Reyene Menidjel, Nicolas Stadler, Guanfang Tian, Floriane Herit, Florence Niedergang, Sylvie Souès, Luc Buée, Marie-Christine Galas, Xavier Montagutelli, Eliette Bonnefoy
Published 2022-12-01

Overexpression of Wild-Type Human Alpha-Synuclein Causes Metabolism Abnormalities in Thy1-aSYN Transgenic Mice

by Elodie Cuvelier, Mathieu Méquinion, Coline Leghay, William Sibran, Aliçia Stievenard, Alessia Sarchione, Marie-Amandine Bonte, Christel Vanbesien-Mailliot, Odile Viltart, Kevin Saitoski, Emilie Caron, Alexandra Labarthe, Thomas Comptdaer, Pierre Semaille, Hélène Carrié, Eugénie Mutez, Bernard Gressier, Alain Destée, Marie-Christine Chartier-Harlin, Karim Belarbi
Published 2018-10-01

Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation

by Jesús Madero-Pérez, Elena Fdez, Belén Fernández, Antonio J. Lara Ordóñez, Marian Blanca Ramírez, Patricia Gómez-Suaga, Dieter Waschbüsch, Evy Lobbestael, Veerle Baekelandt, Angus C. Nairn, Javier Ruiz-Martínez, Ana Aiastui, Adolfo López de Munain, Pawel Lis, Thomas Comptdaer, Jean-Marc Taymans, Marie-Christine Chartier-Harlin, Alexandria Beilina, Adriano Gonnelli, Mark R. Cookson, Elisa Greggio, Sabine Hilfiker
Published 2018-01-01

Transcriptomic signatures of brain regional vulnerability to Parkinson’s disease

by Keo, D.L. (author), Mahfouz, A.M.E.T.A. (author), Ingrassia, Angela M.T. (author), Meneboo, Jean Pascal (author), Villenet, Celine (author), Mutez, Eugénie (author), Comptdaer, Thomas (author), Lelieveldt, B.P.F. (author), Reinders, M.J.T. (author)
Published 2020