Susceptibility to Zika virus in a Collaborative Cross mouse strain is induced by Irf3 deficiency in vitro but requires other variants in vivo.

by Marie Bourdon, Caroline Manet, Laurine Conquet, Corentin Ramaugé Parra, Etienne Kornobis, Eliette Bonnefoy, Xavier Montagutelli
Published 2023-09-01

Intranasal Exposure to Rift Valley Fever Virus Live-Attenuated Strains Leads to High Mortality Rate in Immunocompetent Mice

by Sandra Lacote, Carole Tamietti, Mehdi Chabert, Marie-Pierre Confort, Laurine Conquet, Coralie Pulido, Noémie Aurine, Camille Baquerre, Adrien Thiesson, Bertrand Pain, Marcelo De Las Heras, Marie Flamand, Xavier Montagutelli, Philippe Marianneau, Maxime Ratinier, Frédérick Arnaud
Published 2022-11-01

Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta resp...

by Caroline Manet, Zeyni Mansuroglu, Laurine Conquet, Violaine Bortolin, Thomas Comptdaer, Helena Segrt, Marie Bourdon, Reyene Menidjel, Nicolas Stadler, Guanfang Tian, Floriane Herit, Florence Niedergang, Sylvie Souès, Luc Buée, Marie-Christine Galas, Xavier Montagutelli, Eliette Bonnefoy
Published 2022-12-01

A mRNA Vaccine Encoding for a RBD 60-mer Nanoparticle Elicits Neutralizing Antibodies and Protective Immunity Against the SARS-CoV-2 Delta Variant in Transgenic K18-hACE2 Mice

by Pascal Brandys, Xavier Montagutelli, Irena Merenkova, Güliz T. Barut, Güliz T. Barut, Volker Thiel, Volker Thiel, Volker Thiel, Nicholas J. Schork, Bettina Trüeb, Bettina Trüeb, Laurine Conquet, Aihua Deng, Aleksandar Antanasijevic, Hyun-Ku Lee, Martine Valière, Anoop Sindhu, Gita Singh, Jens Herold
Published 2022-07-01

A live measles-vectored COVID-19 vaccine induces strong immunity and protection from SARS-CoV-2 challenge in mice and hamsters

by Phanramphoei N. Frantz, Aleksandr Barinov, Claude Ruffié, Chantal Combredet, Valérie Najburg, Guilherme Dias de Melo, Florence Larrous, Lauriane Kergoat, Samaporn Teeravechyan, Anan Jongkaewwattana, Emmanuelle Billon-Denis, Jean-Nicolas Tournier, Matthieu Prot, Laurine Levillayer, Laurine Conquet, Xavier Montagutelli, Magali Tichit, David Hardy, Priyanka Fernandes, Hélène Strick-Marchand, James Di Santo, Etienne Simon-Lorière, Hervé Bourhy, Frédéric Tangy
Published 2021-11-01