Mutations in epigenetic regulators including SETD2 are gained during relapse in pediatric acute lymphoblastic leukemia

by Mar, Brenton G, Bullinger, Lars B, McLean, Kathleen M, Grauman, Peter V, Harris, Marian H, Stevenson, Kristen, Neuberg, Donna S, Sinha, Amit U, Sallan, Stephen E, Silverman, Lewis B, Kung, Andrew L, Nigro, Luca Lo, Ebert, Benjamin L, Armstrong, Scott A
Published 2014

MYBL2 is a sub-haploinsufficient tumor suppressor gene in myeloid malignancy.

by Heinrichs, Stefan, Conover, Lillian F, Bueso-Ramos, Carlos E, Kilpivaara, Outi, Stevenson, Kristen, Neuberg, Donna, Loh, Mignon L, Wu, Wen-Shu, Rodig, Scott J, Garcia-Manero, Guillermo, Kantarjian, Hagop M, Look, A Thomas
Published 2013

PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA

by Day, Tovah A., Layer, Jacob V., Cleary, J. Patrick, Guha, Srijoy, Stevenson, Kristen E., Tivey, Trevor, Kim, Sunhee, Schinzel, Anna C., Izzo, Francesca, Doench, John, Root, David E., Hahn, William C., Price, Brendan D., Weinstock, David M.
Published 2017

PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia.

by Ariës, Ingrid M, Bodaar, Kimberly, Karim, Salmaan A, Chonghaile, Triona Ni, Hinze, Laura, Burns, Melissa A, Pfirrmann, Maren, Degar, James, Landrigan, Jack T, Balbach, Sebastian, Peirs, Sofie, Menten, Björn, Isenhart, Randi, Stevenson, Kristen E, Neuberg, Donna S, Devidas, Meenakshi, Loh, Mignon L, Hunger, Stephen P, Teachey, David T, Rabin, Karen R, Winter, Stuart S, Dunsmore, Kimberly P, Wood, Brent L, Silverman, Lewis B, Sallan, Stephen E, Van Vlierberghe, Pieter, Orkin, Stuart H, Knoechel, Birgit, Letai, Anthony G, Gutierrez, Alejandro
Published 2018

Locally Disordered Methylation Forms the Basis of Intratumor Methylome Variation in Chronic Lymphocytic Leukemia

by Landau, Dan A., Clement, Kendell, Ziller, Michael J., Boyle, Patrick, Fan, Jean, Gu, Hongcang, Stevenson, Kristen, Sougnez, Carrie, Wang, Lili, Li, Shuqiang, Kotliar, Dylan, Zhang, Wandi, Ghandi, Mahmoud, Garraway, Levi, Fernandes, Stacey M., Livak, Kenneth J., Gabriel, Stacey, Gnirke, Andreas, Brown, Jennifer R., Neuberg, Donna, Kharchenko, Peter V., Hacohen, Nir, Getz, Gad, Meissner, Alexander, Wu, Catherine J., Lander, Eric Steven
Published 2017

Locally Disordered Methylation Forms the Basis of Intratumor Methylome Variation in Chronic Lymphocytic Leukemia

by Landau, Dan Avi, Clement, Kendell, Ziller, Michael Johannes, Boyle, Patrick, Fan, Jean, Gu, Hongcang, Stevenson, Kristen, Sougnez, Carrie, Wang, Lili, Li, Shuqiang, Kotliar, Dylan, Zhang, Wandi, Ghandi, Mahmoud, Garraway, Levi Alexander, Fernandes, Stacey M., Livak, Kenneth J., Gabriel, Stacey, Gnirke, Andreas, Lander, Eric Steven, Brown, Jennifer Ruth, Neuberg, Donna S., Kharchenko, Peter Vasili, Hacohen, Nir, Getz, Gad A, Meissner, Alexander, Wu, Catherine J.
Published 2017

Polymerase δ promotes chromosomal rearrangements and imprecise double-strand break repair

by Layer, Jacob V, Debaize, Lydie, Van Scoyk, Alexandria, House, Nealia C, Brown, Alexander J, Liu, Yunpeng, Stevenson, Kristen E, Hemann, Michael, Roberts, Steven A, Price, Brendan D, Weinstock, David M, Day, Tovah A
Published 2021

Mechanisms of lymphoma clearance induced by high-dose alkylating agents

by Lossos, Chen, Liu, Yunpeng, Kolb, Kellie E, Christie, Amanda L, van Scoyk, Alexandria, Prakadan, Sanjay M, Shigemori, Kay, Stevenson, Kristen E, Morrow, Sara, Plana, Olivia D, Fraser, Cameron, Jones, Kristen L, Liu, Huiyun, Pallasch, Christian P, Modiste, Rebecca, Nguyen, Quang-De, Craig, Jeffrey W, Morgan, Elizabeth A, Vega, Francisco, Aster, Jon C, Sarosiek, Kristopher A, Shalek, Alex K, Hemann, Michael T, Weinstock, David M
Published 2021

Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia

by Reynolds, Christine, Roderick, Justine E., LaBelle, James L., Bird, Gregory, Mathieu, Ronald, Bodaar, Kimberly, Colon, Diana, Pyati, Ujwal, Stevenson, Kristen E., Qi, Jun, Harris, Marian, Silverman, Lewis B., Sallan, Stephen E., Bradner, James E., Neuberg, Donna S., Look, A. Thomas, Walensky, Loren D., Kelliher, Michelle A., Gutierrez, Alejandro
Published 2015

Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models

by Ng, Samuel Y., Yoshida, Noriaki, Christie, Amanda L., Ghandi, Mahmoud, Dharia, Neekesh V., Dempster, Joshua, Murakami, Mark, Shigemori, Kay, Morrow, Sara N., Van Scoyk, Alexandria, Cordero, Nicolas A., Stevenson, Kristen E., Puligandla, Maneka, Haas, Brian, Lo, Christopher, Meyers, Robin, Gao, Galen, Cherniack, Andrew, Louissaint, Abner, Nardi, Valentina, Thorner, Aaron R., Long, Henry, Qiu, Xintao, Morgan, Elizabeth A., Dorfman, David M., Fiore, Danilo, Jang, Julie, Epstein, Alan L., Dogan, Ahmet, Zhang, Yanming, Horwitz, Steven M., Jacobsen, Eric D., Santiago, Solimar, Ren, Jian-Guo, Guerlavais, Vincent, Annis, D. Allen, Aivado, Manuel, Saleh, Mansoor N., Mehta, Amitkumar, Tsherniak, Aviad, Root, David, Vazquez, Francisca, Hahn, William C., Inghirami, Giorgio, Aster, Jon C., Weinstock, David M., Koch, Raphael
Published 2018

Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia

by Landau, Dan A., Carter, Scott L., Stojanov, Petar, McKenna, Aaron, Stevenson, Kristen, Lawrence, Michael S., Sougnez, Carrie, Stewart, Chip, Sivachenko, Andrey, Wang, Lili, Wan, Youzhong, Zhang, Wandi, Shukla, Sachet A., Vartanov, Alexander, Fernandes, Stacey M., Saksena, Gordon, Cibulskis, Kristian, Tesar, Bethany, Gabriel, Stacey B., Hacohen, Nir, Meyerson, Matthew L., Neuberg, Donna S., Brown, Jennifer R., Getz, Gad, Wu, Catherine J., Lander, Eric Steven
Published 2014

Reduced Expression of Ribosomal Proteins Relieves MicroRNA-Mediated Repression

by Janas, Maja M., Love, Tara, Harris, Abigail S., Stevenson, Kristen, Semmelmann, Karlheinz, Shaffer, Jonathan M., Chen, Po-Hao, Doench, John G., Yerramilli, Subrahmanyam V.B.K., Neuberg, Donna S., Iliopoulos, Dimitrios, Novina, Carl D., Wang, Eric T, Housman, David E, Burge, Christopher B
Published 2014

Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 lysine 27 trimethylation

by Lane, Andrew A., Chapuy, Bjoern, Lin, Charles Y., Tivey, Trevor, Li, Hubo, Townsend, Elizabeth C., van Bodegom, Diederik, Day, Tovah A., Wu, Shuo-Chieh, Liu, Huiyun, Yoda, Akinori, Alexe, Gabriela, Schinzel, Anna C., Sullivan, Timothy J., Malinge, Sébastien, Taylor, Jordan E., Stegmaier, Kimberly, Jaffe, Jacob D., Bustin, Michael, te Kronnie, Geertruy, Izraeli, Shai, Harris, Marian, Stevenson, Kristen E., Neuberg, Donna, Silverman, Lewis B., Sallan, Stephen E., Bradner, James E., Hahn, William C., Crispino, John D., Pellman, David, Weinstock, David M.
Published 2015

CD40L-Tri, a novel formulation of recombinant human CD40L that effectively activates B cells

by Naito, Masayasu, Hainz, Ursula, Burkhardt, Ute E., Fu, Buyin, Ahove, Deborah, Stevenson, Kristen E., Rajasagi, Mohini, Zhu, Baogong, Alonso, Anselmo, Witten, Elizabeth, Matsuoka, Ken-ichi, Neuberg, Donna, Duke-Cohan, Jonathan S., Wu, Cathy Ju-Ying, Freeman, Gordon James
Published 2013

TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups.

by Haase, Detlef, Stevenson, Kristen E, Neuberg, Donna, Maciejewski, Jaroslaw P, Nazha, Aziz, Sekeres, Mikkael A, Ebert, Benjamin L, Garcia-Manero, Guillermo, Haferlach, Claudia, Haferlach, Torsten, Kern, Wolfgang, Ogawa, Seishi, Nagata, Yasunobu, Yoshida, Kenichi, Graubert, Timothy A, Walter, Matthew J, List, Alan F, Komrokji, Rami S, Padron, Eric, Sallman, David, Papaemmanuil, Elli, Campbell, Peter J, Savona, Michael R, Seegmiller, Adam, Adès, Lionel, Fenaux, Pierre, Shih, Lee-Yung, Bowen, David, Groves, Michael J, Tauro, Sudhir, Fontenay, Michaela, Kosmider, Olivier, Bar-Natan, Michal, Steensma, David, Stone, Richard, Heuser, Michael, Thol, Felicitas, Cazzola, Mario, Malcovati, Luca, Karsan, Aly, Ganster, Christina, Hellström-Lindberg, Eva, Boultwood, Jacqueline, Pellagatti, Andrea, Santini, Valeria, Quek, Lynn, Vyas, Paresh, Tüchler, Heinz, Greenberg, Peter L, Bejar, Rafael, International Working Group for MDS Molecular Prognostic Committee
Published 2019

Bone marrow transplantation for adolescents and young adults with sickle cell disease: Results of a prospective multicenter pilot study.

by Krishnamurti, Lakshmanan, Neuberg, Donna S, Sullivan, Keith M, Kamani, Naynesh R, Abraham, Allistair, Campigotto, Federico, Zhang, Wandi, Dahdoul, Thabat, De Castro, Laura, Parikh, Suhag, Bakshi, Nitya, Haight, Ann, Hassell, Kathryn L, Loving, Rebekah, Rosenthal, Joseph, Smith, Shannon L, Smith, Wally, Spearman, Marcus, Stevenson, Kristen, Wu, Catherine J, Wiedl, Christina, Waller, Edmund K, Walters, Mark C
Published 2019

SF3B1 and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia

by Wang, Lili, Lawrence, Michael S., Wan, Youzhong, Stojanov, Petar, Sougnez, Carrie, Stevenson, Kristen, Werner, Lillian, Sivachenko, Andrey, DeLuca, David S., Zhang, Li, Zhang, Wandi, Vartanov, Alexander R., Fernandes, Stacey M., Goldstein, Natalie R., Folco, Eric G., Cibulskis, Kristian, Tesar, Bethany, Sievers, Quinlan L., Shefler, Erica, Gabriel, Stacey B., Hacohen, Nir, Reed, Robin, Meyerson, Matthew L., Golub, Todd R., Neuberg, Donna S., Brown, Jennifer R., Getz, Gad, Wu, Catherine J., Lander, Eric S., Lander, Eric Steven
Published 2014