CHK1 inhibition as a strategy for targeting fanconi anemia (FA) DNA repair pathway deficient tumors

by Look A Thomas, Sidi Samuel, Kennedy Richard D, Chen Clark C, D'Andrea Alan
Published 2009-04-01

ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry

by Wang, Lu, Tan, Tze King, Durbin, Adam D, Zimmerman, Mark W, Abraham, Brian J, Tan, Shi Hao, Ngoc, Phuong Cao Thi, Weichert-Leahey, Nina, Akahane, Koshi, Lawton, Lee N, Rokita, Jo Lynne, Maris, John M, Young, Richard A, Look, A Thomas, Sanda, Takaomi
Published 2021

Correction: Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma.

by Prutsch, Nicole, Gurnhofer, Elisabeth, Suske, Tobias, Liang, Huan Chang, Schlederer, Michaela, Roos, Simone, Wu, Lawren C, Simonitsch-Klupp, Ingrid, Alvarez-Hernandez, Andrea, Kornauth, Christoph, Leone, Dario A, Svinka, Jasmin, Eferl, Robert, Limberger, Tanja, Aufinger, Astrid, Shirsath, Nitesh, Wolf, Peter, Hielscher, Thomas, Sternberg, Christina, Aberger, Fritz, Schmoellerl, Johannes, Stoiber, Dagmar, Strobl, Birgit, Jäger, Ulrich, Staber, Philipp B, Grebien, Florian, Moriggl, Richard, Müller, Mathias, Inghirami, Giorgio G, Sanda, Takaomi, Look, A Thomas, Turner, Suzanne D, Kenner, Lukas, Merkel, Olaf
Published 2021

Correction: Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma

by Prutsch, Nicole, Gurnhofer, Elisabeth, Suske, Tobias, Liang, Huan Chang, Schlederer, Michaela, Roos, Simone, Wu, Lawren C., Simonitsch-Klupp, Ingrid, Alvarez-Hernandez, Andrea, Kornauth, Christoph, Leone, Dario A., Svinka, Jasmin, Eferl, Robert, Limberger, Tanja, Aufinger, Astrid, Shirsath, Nitesh, Wolf, Peter, Hielscher, Thomas, Sternberg, Christina, Aberger, Fritz, Schmoellerl, Johannes, Stoiber, Dagmar, Strobl, Birgit, Jäger, Ulrich, Staber, Philipp B., Grebien, Florian, Moriggl, Richard, Müller, Mathias, Inghirami, Giorgio G., Sanda, Takaomi, Look, A. Thomas, Turner, Suzanne D., Kenner, Lukas, Merkel, Olaf
Published 2020

Small genomic insertions form enhancers that misregulate oncogenes

by Abraham, Brian J., Hnisz, Denes, Weintraub, Abraham S., Kwiatkowski, Nicholas, Li, Charles H., Li, Zhaodong, Weichert-Leahey, Nina, Rahman, Sunniyat, Liu, Yu, Etchin, Julia, Li, Benshang, Shen, Shuhong, Lee, Tong Ihn, Zhang, Jinghui, Look, A. Thomas, Mansour, Marc R., Young, Richard A.
Published 2017

T-Lymphoblastic Lymphoma Cells Express High Levels of BCL2, S1P1, and ICAM1, Leading to a Blockade of Tumor Cell Intravasation

by Feng, Hui, Stachura, David L., White, Richard, Gutierrez, Alejandro, Zhang, Lu, Sanda, Takaomi, Jette, Cicely A., Testa, Joseph R., Neuberg, Donna S., Langenau, David M., Kutok, Jeffery Lorne, Zon, Leonard Ira, Traver, David, Fleming, Mark Daniel, Kanki, John P., Look, A. Thomas
Published 2014

Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish

by Tang, Qin, Moore, John C., Ignatius, Myron S., Tenente, Inês M., Hayes, Madeline N., Garcia, Elaine G., Torres Yordán, Nora, Bourque, Caitlin, He, Shuning, Blackburn, Jessica S., Look, A. Thomas, Houvras, Yariv, Langenau, David M.
Published 2016

Regulation of Neural Crest Development by Chemically Targetable Pathways

by Ciarlo, Christie
Published 2019

ATM-deficient Thymic Lymphoma is Associated with Aberrant tcrd Rearrangement and Gene Amplification

by Bassing, Craig H., Brush, James W., Patel, Harin, Goff, Peter H., Gatti, Richard A., Zha, Shan, Sanda, Takaomi, Murphy, Michael M., Tepsuporn, Suprawee, Look, A. Thomas, Alt, Frederick W.
Published 2011

LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors

by Tao, Ting, Shi, Hui, Mariani, Luca, Abraham, Brian J., Durbin, Adam D., Zimmerman, Mark W., Powers, John T., Missios, Pavlos, Ross, Kenneth N., Perez-Atayde, Antonio R., Bulyk, Martha L., Young, Richard A., Daley, George Q., Look, A. Thomas
Published 2022

LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors

by Tao, Ting, Shi, Hui, Mariani, Luca, Abraham, Brian J, Durbin, Adam D, Zimmerman, Mark W, Powers, John T, Missios, Pavlos, Ross, Kenneth N, Perez-Atayde, Antonio R, Bulyk, Martha L, Young, Richard A, Daley, George Q, Look, A Thomas
Published 2021

HSP90 inhibition leads to degradation of the TYK2 kinase and apoptotic cell death in T-cell acute lymphoblastic leukemia

by Akahane, Koshi, Sanda, Takaomi, Mansour, Marc R., Radimerski, Thomas, DeAngelo, Daniel J., Weinstock, David M., Look, A. Thomas
Published 2016

The Chromatin Remodeling Factor CHD5 Is a Transcriptional Repressor of WEE1

by Quan, Jinhua, Adelmant, Guillaume, Marto, Jarrod A., Look, A. Thomas, Yusufzai, Timur
Published 2014

A Zebrafish Model of Myelodysplastic Syndrome Produced through tet2 Genomic Editing

by Gjini, Evisa, Mansour, Marc, Sander, Jeffry, Moritz, Nadine, Nguyen, Ashley, Kesarsing, Michiel, Gans, Emma, He, Shuning, Chen, Si, Ko, Myunggon, Kuang, You-Yi, Yang, Song, Zhou, Yi, Rodig, Scott, Zon, Leonard, Joung, J. Keith, Rao, Anjana, Look, A. Thomas
Published 2019

Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP-related domain

by He, Shuning, Mansour, Marc R, Zimmerman, Mark W, Ki, Dong Hyuk, Layden, Hillary M, Akahane, Koshi, Gjini, Evisa, de Groh, Eric D, Perez-Atayde, Antonio R, Zhu, Shizhen, Epstein, Jonathan A, Look, A Thomas
Published 2016

CHK1 Inhibition as a Strategy for Targeting Fanconi Anemia (FA) DNA Repair Pathway Deficient Tumors

by Chen, Clark C, Kennedy, Richard D, Sidi, Samuel, Look, A. Thomas, D'Andrea, Alan David
Published 2012

Antileukemic Activity of Nuclear Export Inhibitors that Spare Normal Hematopoietic Cells

by Etchin, Julia, Sun, Q, Kentsis, Alex, Farmer, A, Zhang, Z C, Sanda, Takaomi, Mansour, M R, Barcelo, C, McCauley, D, Kauffman, M, Shacham, S, Christie, A L, Kung, A L, Rodig, Scott J., Chook, Y M, Look, A. Thomas
Published 2013

Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency

by Blackburn, Jessica S., Liu, Sali, Raiser, Dave Michael, Martinez, Sarah A., Feng, Hui, Meeker, Nathan D., Gentry, Jeffery, Neuberg, Donna S., Look, A. Thomas, Ramaswamy, Sridhar, Bernards, Andre, Trede, Nikolaus S., Langenau, David M.
Published 2013

Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia

by Reynolds, Christine, Roderick, Justine E., LaBelle, James L., Bird, Gregory, Mathieu, Ronald, Bodaar, Kimberly, Colon, Diana, Pyati, Ujwal, Stevenson, Kristen E., Qi, Jun, Harris, Marian, Silverman, Lewis B., Sallan, Stephen E., Bradner, James E., Neuberg, Donna S., Look, A. Thomas, Walensky, Loren D., Kelliher, Michelle A., Gutierrez, Alejandro
Published 2015

Hematopoietic gene expression profile in zebrafish kidney marrow

by Song, Huai-Dong, Sun, Xiao-Jian, Deng, Min, Zhang, Guo-Wei, Zhou, Yi, Wu, Xin-Yan, Sheng, Yan, Chen, Yi, Ruan, Zheng, Jiang, Chun-Lei, Fan, Hui-Yong, Zon, Leonard I., Kanki, John P., Liu, Ting Xi, Look, A. Thomas, Chen, Zhu
Published 2019