Function, Regulation, and Dysfunction of Intrinsically Disordered Proteins

by Giuliana Fusco, Stefano Gianni
Published 2021-02-01

An Outlook on the Complexity of Protein Morphogenesis in Health and Disease

by Maurizio Brunori, Maurizio Brunori, Stefano Gianni
Published 2022-06-01

Modulation of Measles Virus NTAIL Interactions through Fuzziness and Sequence Features of Disordered Binding Sites

by Christophe Bignon, Francesca Troilo, Stefano Gianni, Sonia Longhi
Published 2018-12-01

InSiDDe: A Server for Designing Artificial Disordered Proteins

by Antoine Schramm, Philippe Lieutaud, Stefano Gianni, Sonia Longhi, Christophe Bignon
Published 2017-12-01

The Effect of Proline <i>cis</i>-<i>trans</i> Isomerization on the Folding of the C-Terminal SH2 Domain from p85

by Francesca Troilo, Francesca Malagrinò, Lorenzo Visconti, Angelo Toto, Stefano Gianni
Published 2019-12-01

Experimental Characterization of the Interaction between the N-Terminal SH3 Domain of Crkl and C3G

by Livia Pagano, Francesca Malagrinò, Caterina Nardella, Stefano Gianni, Angelo Toto
Published 2021-12-01

Unveiling the Molecular Basis of the Noonan Syndrome-Causing Mutation T42A of SHP2

by Angelo Toto, Francesca Malagrinò, Lorenzo Visconti, Francesca Troilo, Stefano Gianni
Published 2020-01-01

Emerging Therapeutic Agents for Colorectal Cancer

by Marianna Nalli, Michela Puxeddu, Giuseppe La Regina, Stefano Gianni, Romano Silvestri
Published 2021-12-01

Understanding the Binding Induced Folding of Intrinsically Disordered Proteins by Protein Engineering: Caveats and Pitfalls

by Francesca Malagrinò, Lorenzo Visconti, Livia Pagano, Angelo Toto, Francesca Troilo, Stefano Gianni
Published 2020-05-01

Double Mutant Cycles as a Tool to Address Folding, Binding, and Allostery

by Livia Pagano, Angelo Toto, Francesca Malagrinò, Lorenzo Visconti, Per Jemth, Stefano Gianni
Published 2021-01-01

Demonstration of Binding Induced Structural Plasticity in a SH2 Domain

by Lorenzo Visconti, Angelo Toto, James A. Jarvis, Francesca Troilo, Francesca Malagrinò, Alfonso De Simone, Stefano Gianni
Published 2020-05-01

On the Effects of Disordered Tails, Supertertiary Structure and Quinary Interactions on the Folding and Function of Protein Domains

by Francesca Malagrinò, Valeria Pennacchietti, Daniele Santorelli, Livia Pagano, Caterina Nardella, Awa Diop, Angelo Toto, Stefano Gianni
Published 2022-01-01

Tolerance of protein folding to a circular permutation in a PDZ domain.

by Greta Hultqvist, Avinash S Punekar, Angela Morrone, Celestine N Chi, Ake Engström, Maria Selmer, Stefano Gianni, Per Jemth
Published 2012-01-01

Folding and Binding Kinetics of the Tandem of SH2 Domains from SHP2

by Livia Pagano, Valeria Pennacchietti, Francesca Malagrinò, Mariana Di Felice, Julian Toso, Elena Puglisi, Stefano Gianni, Angelo Toto
Published 2024-06-01

Regulation of the Human Phosphatase PTPN4 by the inter-domain linker connecting the PDZ and the phosphatase domains

by Célia Caillet-Saguy, Angelo Toto, Raphael Guerois, Pierre Maisonneuve, Eva di Silvio, Kristi Sawyer, Stefano Gianni, Nicolas Wolff
Published 2017-08-01

Investigating the Molecular Basis of the Aggregation Propensity of the Pathological D76N Mutant of Beta-2 Microglobulin: Role of the Denatured State

by Lorenzo Visconti, Francesca Malagrinò, Luca Broggini, Chiara Maria Giulia De Luca, Fabio Moda, Stefano Gianni, Stefano Ricagno, Angelo Toto
Published 2019-01-01

Patient hesitancy in perioperative clinical trial enrollment during the COVID-19 pandemic.

by Josue D Chirinos, Isabella S Turco, Raffaele Di Fenza, Stefano Gianni, Grant M Larson, Joseph F Swingle, Oluwaseun Akeju, Lorenzo Berra
Published 2023-01-01

SH2 Domains: Folding, Binding and Therapeutical Approaches

by Awa Diop, Daniele Santorelli, Francesca Malagrinò, Caterina Nardella, Valeria Pennacchietti, Livia Pagano, Lucia Marcocci, Paola Pietrangeli, Stefano Gianni, Angelo Toto
Published 2022-12-01

Folding and Binding Mechanisms of the SH2 Domain from Crkl

by Caterina Nardella, Angelo Toto, Daniele Santorelli, Livia Pagano, Awa Diop, Valeria Pennacchietti, Paola Pietrangeli, Lucia Marcocci, Francesca Malagrinò, Stefano Gianni
Published 2022-07-01

Addressing the Binding Mechanism of the Meprin and TRAF-C Homology Domain of the Speckle-Type POZ Protein Using Protein Engineering

by Awa Diop, Paola Pietrangeli, Valeria Pennacchietti, Livia Pagano, Angelo Toto, Mariana Di Felice, Sara Di Matteo, Lucia Marcocci, Francesca Malagrinò, Stefano Gianni
Published 2023-12-01