Little ones can do big things: Small molecule inhibitors target PTPN2/PTPN1 for tumor immunotherapy

by Junyu Wang, Shugang Qin, Anren Zhang
Published 2024-06-01

Manipulating mitochondrial electron flow: a novel approach to enhance tumor immunogenicity

by Junyu Wang, Anren Zhang, Min Wu, Shugang Qin
Published 2024-03-01

SHIP-1 Regulates Phagocytosis and M2 Polarization Through the PI3K/Akt–STAT5–Trib1 Circuit in Pseudomonas aeruginosa Infection

by Shugang Qin, Shugang Qin, Jiaxin Li, Jiaxin Li, Chuanmin Zhou, Breanna Privratsky, Jacob Schettler, Xin Deng, Zhenwei Xia, Yong Zeng, Hong Wu, Min Wu
Published 2020-03-01

Prenatal Exposure to Lipopolysaccharide Results in Myocardial Fibrosis in Rat Offspring

by Xin Chen, Yujie Tang, Meng Gao, Shugang Qin, Jianzhi Zhou, Xiaohui Li
Published 2015-05-01

oprC Impairs Host Defense by Increasing the Quorum-Sensing-Mediated Virulence of Pseudomonas aeruginosa

by Pan Gao, Pan Gao, Kai Guo, Qinqin Pu, Qinqin Pu, Zhihan Wang, Zhihan Wang, Ping Lin, Shugang Qin, Shugang Qin, Nadeem Khan, Junguk Hur, Haihua Liang, Min Wu
Published 2020-08-01

Herbal Medicine Nanocrystals: A Potential Novel Therapeutic Strategy

by Mengran Guo, Shugang Qin, Shiyan Wang, Min Sun, Huiling Yang, Xinchun Wang, Ping Fan, Zhaohui Jin
Published 2023-08-01

Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics

by Shugang Qin, Wen Xiao, Chuanmin Zhou, Qinqin Pu, Xin Deng, Lefu Lan, Haihua Liang, Xiangrong Song, Min Wu
Published 2022-06-01

Bitter receptor TAS2R138 facilitates lipid droplet degradation in neutrophils during Pseudomonas aeruginosa infection

by Qinqin Pu, Kai Guo, Ping Lin, Zhihan Wang, Shugang Qin, Pan Gao, Colin Combs, Nadeem Khan, Zhenwei Xia, Min Wu
Published 2021-06-01

mRNA-based therapeutics: powerful and versatile tools to combat diseases

by Shugang Qin, Xiaoshan Tang, Yuting Chen, Kepan Chen, Na Fan, Wen Xiao, Qian Zheng, Guohong Li, Yuqing Teng, Min Wu, Xiangrong Song
Published 2022-05-01

Sodium alginate coating simultaneously increases the biosafety and immunotherapeutic activity of the cationic mRNA nanovaccine

by Xing Duan, Yi Zhang, Mengran Guo, Na Fan, Kepan Chen, Shugang Qin, Wen Xiao, Qian Zheng, Hai Huang, Xiawei Wei, Yuquan Wei, Xiangrong Song
Published 2023-03-01

High-throughput screen reveals sRNAs regulating crRNA biogenesis by targeting CRISPR leader to repress Rho termination

by Ping Lin, Qinqin Pu, Qun Wu, Chuanmin Zhou, Biao Wang, Jacob Schettler, Zhihan Wang, Shugang Qin, Pan Gao, Rongpeng Li, Guoping Li, Zhenyu Cheng, Lefu Lan, Jianxin Jiang, Min Wu
Published 2019-08-01

Dual-targeting tigecycline nanoparticles for treating intracranial infections caused by multidrug-resistant Acinetobacter baumannii

by Xing Lan, Shugang Qin, Huan Liu, Mengran Guo, Yupei Zhang, Xinyang Jin, Xing Duan, Min Sun, Zhenjun Liu, Wenyan Wang, Qian Zheng, Xuelian Liao, Jinpeng Chen, Yan Kang, Yongmei Xie, Xiangrong Song
Published 2024-03-01

A novel heterologous receptor-binding domain dodecamer universal mRNA vaccine against SARS-CoV-2 variants

by Shugang Qin, Hai Huang, Wen Xiao, Kepan Chen, Xi He, Xiaoshan Tang, Zhiying Huang, Yupei Zhang, Xing Duan, Na Fan, Qian Zheng, Min Wu, Guangwen Lu, Yuquan Wei, Xiawei Wei, Xiangrong Song
Published 2023-10-01

Efficient signal sequence of mRNA vaccines enhances the antigen expression to expand the immune protection against viral infection

by Yupei Zhang, Songhui Zhai, Hai Huang, Shugang Qin, Min Sun, Yuting Chen, Xing Lan, Guohong Li, Zhiying Huang, Denggang Wang, Yaoyao Luo, Wen Xiao, Hao Li, Xi He, Meiwan Chen, Xingchen Peng, Xiangrong Song
Published 2024-05-01

Engineered Bacteriophages Containing Anti-CRISPR Suppress Infection of Antibiotic-Resistant P. aeruginosa

by Shugang Qin, Yongan Liu, Yuting Chen, Jinrong Hu, Wen Xiao, Xiaoshan Tang, Guohong Li, Ping Lin, Qinqin Pu, Qun Wu, Chuanmin Zhou, Biao Wang, Pan Gao, Zhihan Wang, Aixin Yan, Khan Nadeem, Zhenwei Xia, Min Wu
Published 2022-10-01

A novel deep generative model for mRNA vaccine development: Designing 5′ UTRs with N1-methyl-pseudouridine modification

by Xiaoshan Tang, Miaozhe Huo, Yuting Chen, Hai Huang, Shugang Qin, Jiaqi Luo, Zeyi Qin, Xin Jiang, Yongmei Liu, Xing Duan, Ruohan Wang, Lingxi Chen, Hao Li, Na Fan, Zhongshan He, Xi He, Bairong Shen, Shuai Cheng Li, Xiangrong Song
Published 2024-04-01