Integrative genome-wide expression profiling identifies three distinct molecular subgroups of renal cell carcinoma with different patient outcome

by Beleut Manfred, Zimmermann Philip, Baudis Michael, Bruni Nicole, Bühlmann Peter, Laule Oliver, Luu Van-Duc, Gruissem Wilhelm, Schraml Peter, Moch Holger
Published 2012-07-01

Periostin is up-regulated in high grade and high stage prostate cancer

by Schraml Peter, Gerhardt Josefine, Mortezavi Ashkan, Hermanns Thomas, Riener Marc-Oliver, Seifert Hans-Helge, Stephan Carsten, Wild Peter J, Fritzsche Florian R, Tischler Verena, Jung Klaus, Moch Holger, Soltermann Alex, Kristiansen Glen
Published 2010-06-01

Von-Hippel-Lindau-Gen-Mutationstypen: Assoziation mit Genexpressionssignaturen in klarzelligen Nierenzellkarzinomen

by Luu, Van Duc, Fischer, Bernd, Teichman, Adriana von, Boysen, Gunter, Mertz, Kirsten, Zimmermann, Philip, Moch, Holger, Schraml, Peter
Published 2008

Three-dimensional imaging mass cytometry for highly multiplexed molecular and cellular mapping of tissues and the tumor microenvironment

by Kuett, Laura, Catena, Raúl, Özcan, Alaz, Plüss, Alex, Cancer Grand Challenges IMAXT Consortium, Schraml, Peter, Moch, Holger, de Souza, Natalie, Bodenmiller, Bernd
Published 2022

Combined mutation of Vhl and Trp53 causes renal cysts and tumours in mice

by Albers, Joachim, Rajski, Michal, Schönenberger, Désirée, Harlander, Sabine, Schraml, Peter, von Teichman, Adriana, Georgiev, Strahil, Wild, Peter J., Moch, Holger, Krek, Wilhelm, Frew, Ian J.
Published 2013

IL-8 and CXCR1 expression is associated with cancer stem cell-like properties of clear cell renal cancer

by Corrò, Claudia, Healy, Marc E., Engler, Stefanie, Bodenmiller, Bernd, Li, Zhe, Schraml, Peter, Weber, Achim, Frew, Ian J., Rechsteiner, Markus, Moch, Holger
Published 2019

Statistical tests for intra-tumour clonal co-occurrence and exclusivity

by Kuipers, Jack, Moore, Ariane L., Jahn, Katharina, Schraml, Peter, Wang, Feng, Morita, Kiyomi, Futreal, P. Andrew, Takahashi, Koichi, Beisel, Christian, Moch, Holger, Beerenwinkel, Niko; id_orcid0000-0002-0573-6119
Published 2021

Opposing effects of cancer type-specific SPOP mutations on BET protein degradation and sensitivity to BET inhibitors

by Janouskova, Hana, Tekle, Geniver El, Bellini, Elisa, Udeshi, Namrata D., Rinaldi, Anna, Ulbricht, Anna, Bernasocchi, Tiziano, Civenni, Gianluca, Losa, Marco, Svinkina, Tanya, Bielski, Craig M., Kryukov, Gregory V., Cascione, Luciano, Napoli, Sara, Enchev, Radoslav I., Mutch, David G., Carney, Michael E., Berchuck, Andrew, Winterhoff, Boris J.N., Broaddus, Russell R., Schraml, Peter, Moch, Holger, Bertoni, Francesco, Catapano, Carlo V., Peter, Matthias, Carr, Steven A., Garraway, Levi A., Wild, Peter J., Theurillat, Jean-Philippe P.
Published 2018

Expression and Mutation Patterns of PBRM1, BAP1 and SETD2 Mirror Specific Evolutionary Subtypes in Clear Cell Renal Cell Carcinoma

by Bihr, Svenja, Ohashi, Riuko, Moore, Ariane L., Rüschoff, Jan H., Beisel, Christian, Hermanns, Thomas, Mischo, Axel, Corro, Claudia, Beyer, Jorg, Beerenwinkel, Niko; id_orcid0000-0002-0573-6119, Moch, Holger, Schraml, Peter
Published 2019

Functional characterization of BC039389-GATM and KLK4-KRSP1 chimeric read-through transcripts which are up-regulated in renal cell cancer

by Pflueger, Dorothee, Mittmann, Christiane, Dehler, Silvia, Rubin, Mark A., Moch, Holger, Schraml, Peter
Published 2015

Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer

by Bernasocchi, Tiziano, El Tekle, Geniver, Bolis, Marco, Mutti, Azzurra, Vallerga, Arianna, Brandt, Laura P., Spriano, Filippo, Svinkina, Tanya, Zoma, Marita, Ceserani, Valentina, Rinaldi, Anna, Janouskova, Hana, Bossi, Daniela, Cavalli, Manuela, Mosole, Simone, Geiger, Roger, Dong, Ze, Yang, Cai-Guang, Albino, Domenico, Rinaldi, Andrea, Schraml, Peter, Linder, Simon, Carbone, Giuseppina M., Alimonti, Andrea; id_orcid0000-0002-9362-2313, Bertoni, Francesco, Moch, Holger, Carr, Steven A., Zwart, Wilbert, Kruithof‑de Julio, Marianna, Rubin, Mark A., Udeshi, Namrata D., Theurillat, Jean-Philippe P.
Published 2021

MiR-99b-5p expression and response to tyrosine kinase inhibitor treatment in clear cell renal cell carcinoma patients

by Lukamowicz-Rajska, Magdalena, Mittmann, Christiane, Prummer, Michael; id_orcid0000-0001-9896-3929, Zhong, Qing, Bedke, Jens, Hennenlotter, Jörg, Stenzl, Arnulf, Mischo, Axel, Bihr, Svenja, Schmidinger, Manuela, Vogl, Ursula, Blume, Iris, Karlo, Christoph, Schraml, Peter, Moch, Holger
Published 2016

Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling

by Wollenick, Kristin, Hu, Jun, Kristiansen, Glen, Schraml, Peter, Rehrauer, Hubert; id_orcid0000-0001-7612-9394, Berchner-Pfannschmidt, Utta, Fandrey, Joachim, Wenger, Roland H., Stiehl, Daniel P.
Published 2012

Integrative genome-wide expression profiling identifies three distinct molecular subgroups of renal cell carcinoma with different patient outcome

by Beleut, Manfred, Zimmermann, Philip, Baudis, Michael, Bruni, Nicole, Bühlmann, Peter, Laule, Oliver, Luu, Van-Duc, Gruissem, Wilhelm; id_orcid0000-0002-1872-2998, Schraml, Peter, Moch, Holger
Published 2012

Classic chromophobe renal cell carcinoma incur a larger number of chromosomal losses than seen in the eosinophilic subtype

by Ohashi, Riuko, Schraml, Peter, Angori, Silvia, Batavia, Aashil A., Rupp, Niels J., Ohe, Chisato, Otsuki, Yoshiro, Kawasaki, Takashi, Kobayashi, Hiroshi, Kobayashi, Kazuhiro, Miyazaki, Tatsuhiko, Shibuya, Hiroyuki, Usuda, Hiroyuki, Umezu, Hajime, Fujishima, Fumiyoshi, Furusato, Bungo, Osakabe, Mitsumasa, Sugai, Tamotsu, Kuroda, Naoto, Tsuzuki, Toyonori, Nagashima, Yoji, Ajioka, Yoichi, Moch, Holger
Published 2019

Identification and Functional Characterization of pVHL-Dependent Cell Surface Proteins in Renal Cell Carcinoma

by Boysen, Gunther, Bausch-Fluck, Damaris; id_orcid0000-0002-7593-2262, Thoma, Claudio R., Nowicka, Anna M., Stiehl, Daniel P., Cima, Igor, Luu, Van-Duc, Teichman, Adriana von, Hermanns, Thomas, Sulser, Tullio, Ingold-Heppner, Barbara, Fankhauser, Niklaus, Wenger, Roland H., Krek, Wilhelm, Schraml, Peter, Wollscheid, Bernd; id_orcid0000-0002-3923-1610, Moch, Holger
Published 2012

Allele Loss and Reduced Expression of CYCLOPS Genes is a Characteristic Feature of Chromophobe Renal Cell Carcinoma

by Ohashi, Riuko, Schraml, Peter, Batavia, Aashil, Angori, Silvia, Simmler, Patrik, Rupp, Niels, Ajioka, Yoichi, Oliva, Esther, Moch, Holger
Published 2019

Detailed simulation of cancer exome sequencing data reveals differences and common limitations of variant callers

by Hofmann, Ariane L., Behr, Jonas, Singer, Jochen, Kuipers, Jack, Beisel, Christian, Schraml, Peter, Moch, Holger, Beerenwinkel, Niko
Published 2017

Tracing Clonal Dynamics Reveals that Two- and Three-dimensional Patient-derived Cell Models Capture Tumor Heterogeneity of Clear Cell Renal Cell Carcinoma

by Bolck, Hella A., Corrò, Claudia, Kahraman, Abdullah, von Teichman, Adriana, Toussaint, Nora C., Kuipers, Jack, Chiovaro, Francesca, Koelzer, Viktor H., Pauli, Chantal, Moritz, Wolfgang, Bode, Peter K., Rechsteiner, Markus, Beerenwinkel, Niko; id_orcid0000-0002-0573-6119, Schraml, Peter, Moch, Holger
Published 2021