Single-cell transcriptomics identifies Mcl-1 as a target for senolytic therapy in cancer

by Troiani, Martina, Colucci, Manuel, D’Ambrosio, Mariantonietta, Guccini, Ilaria, Pasquini, Emiliano, Varesi, Angelica, Valdata, Aurora, Mosole, Simone, Revandkar, Ajinkya, Attanasio, Giuseppe, Rinaldi, Andrea, Rinaldi, Anna, Bolis, Marco, Cippà, Pietro, Alimonti, Andrea; id_orcid0000-0002-9362-2313
Published 2022

How phosphorylation influences E1 subunit pyruvate dehydrogenase: A computational study

by Sgrignani, Jacopo, Chen, Jingjing, Alimonti, Andrea; id_orcid0000-0002-9362-2313, Cavalli, Andrea
Published 2018

Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence

by Revandkar, Ajinkya, Perciato, Maria Luna, Toso, Alberto, Alajati, Abdullah, Chen, Jingjing, Gerber, Hermeto, Dimitrov, Mitko, Rinaldi, Andrea, Delaleu, Nicolas, Pasquini, Emiliano, D'Antuono, Rocco, Pinton, Sandra, Losa, Marco, Gnetti, Letizia, Arribas, Alberto, Fraering, Patrick, Bertoni, Francesco, Nepveu, Alain, Alimonti, Andrea; id_orcid0000-0002-9362-2313
Published 2016

Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer

by Bernasocchi, Tiziano, El Tekle, Geniver, Bolis, Marco, Mutti, Azzurra, Vallerga, Arianna, Brandt, Laura P., Spriano, Filippo, Svinkina, Tanya, Zoma, Marita, Ceserani, Valentina, Rinaldi, Anna, Janouskova, Hana, Bossi, Daniela, Cavalli, Manuela, Mosole, Simone, Geiger, Roger, Dong, Ze, Yang, Cai-Guang, Albino, Domenico, Rinaldi, Andrea, Schraml, Peter, Linder, Simon, Carbone, Giuseppina M., Alimonti, Andrea; id_orcid0000-0002-9362-2313, Bertoni, Francesco, Moch, Holger, Carr, Steven A., Zwart, Wilbert, Kruithof‑de Julio, Marianna, Rubin, Mark A., Udeshi, Namrata D., Theurillat, Jean-Philippe P.
Published 2021

Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer

by Di Mitri, Diletta, Mirenda, Michela, Vasilevska, Jelena, Calcinotto, Arianna, Delaleu, Nicolas, Revandkar, Ajinkya, Gil, Veronica, Boysen, Gunther, Losa, Marco, Mosole, Simone, Pasquini, Emiliano, D’Antuono, Rocco, Masetti, Michela, Zagato, Elena, Chiorino, Giovanna, Ostano, Paola, Rinaldi, Andrea, Gnetti, Letizia, Graupera, Mariona, Martins Figueiredo Fonseca, Ana R., Pereira Mestre, Ricardo, Waugh, David, Barry, Simon, De Bono, Johann, Alimonti, Andrea; id_orcid0000-0002-9362-2313
Published 2019

Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

by Nava Rodrigues, Daniel, Alimonti, Andrea; id_orcid0000-0002-9362-2313, et al.
Published 2018

Targeting PML in triple negative breast cancer elicits growth suppression and senescence

by Arreal, Leire, Piva, Marco, Fernández, Sonia, Revandkar, Ajinkya, Schaub-Clerigué, Ariane, Villanueva, Josep, Zabala-Letona, Amaia, Pujana, Mikel, Astobiza, Ianire, Cortazar, Ana R., Hermanova, Ivana, Bozal-Basterra, Laura, Arruabarrena-Aristorena, Amaia, Crespo, Jana R., Valcarcel-Jimenez, Lorea, Zuñiga-García, Patricia, Canals, Francesc, Torrano, Verónica, Barrio, Rosa, Sutherland, James D., Alimonti, Andrea; id_orcid0000-0002-9362-2313, Martín-Martín, Natalia, Carracedo, Arkaitz
Published 2020

CDCP1 overexpression drives prostate cancer progression and can be targeted in vivo

by Alajati, Abdullah, D’Ambrosio, Mariantonietta, Troiani, Martina, Mosole, Simone, Pellegrini, Laura, Chen, Jingjing, Revandkar, Ajinkya, Bolis, Marco, Theurillat, Jean-Philippe, Guccini, Ilaria, Losa, Marco, Calcinotto, Arianna, de Bernardis, Gaston, Pasquini, Emiliano, D'Antuono, Rocco, Sharp, Adam, Figueiredo, Ines, Nava Rodrigues, Daniel, Welti, Jonathan, Gil, Veronica, Yuan, Wei, Vlajnic, Tatjana, Bubendorf, Lukas, Chiorino, Giovanna, Gnetti, Letizia, Torrano, Verónica, Carracedo, Arkaitz, Camplese, Laura, Hirabayashi, Susumu, Canato, Elena, Pasut, Gianfranco, Montopoli, Monica, Rüschoff, Jan Hendrik, Wild, Peter, Moch, Holger, De Bono, Johann, Alimonti, Andrea; id_orcid0000-0002-9362-2313
Published 2020

Pharmacological Comparative Characterization of REL-1017 (Esmethadone-HCl) and Other NMDAR Channel Blockers in Human Heterodimeric N-Methyl-D-Aspartate Receptors

by Bettini, Ezio, Stahl, Stephen M., De Martin, Sara, Mattarei, Andrea, Sgrignani, Jacopo, Carignani, Corrado, Nola, Selena, Locatelli, Patrizia, Pappagallo, Marco, Inturrisi, Charles E., Bifari, Francesco, Cavalli, Andrea, Alimonti, Andrea; id_orcid0000-0002-9362-2313, Pani, Luca, Fava, Maurizio, Traversa, Sergio, Folli, Franco, Manfredi, Paolo L.
Published 2022

CD38 in Advanced Prostate Cancers

by Drake, Charles G, Guo, Christina, Crespo, Mateus, Gurel, Bora, Dolling, David, Rekowski, Jan, Sharp, Adam, Petremolo, Antonella, Sumanasuriya, Semini, Rodrigues, Daniel N., Ferreira, Ana, Pereira, Rita, Figueiredo, Ines, Mehra, Niven, Lambros, Maryou B.K., Neeb, Antje, Gil, Veronica, Seed, George, Terstappen, Leon, Alimonti, Andrea; id_orcid0000-0002-9362-2313, Drake, Charles G., Yuan, Wei, de Bono, Johann S.
Published 2021