A mutation (−49C>T) in the promoter of the low density lipoprotein receptor gene associated with familial hypercholesterolemia

by Pilar Mozas, Román Galetto, Marta Albajar, Emilio Ros, Miguel Pocoví, José C. Rodríguez-Rey
Published 2002-01-01

Pre-TCRα supports CD3-dependent reactivation and expansion of TCRα-deficient primary human T-cells

by Román Galetto, Celine Lebuhotel, Laurent Poirot, Agnès Gouble, Maria L Toribio, Julianne Smith, Andrew Scharenberg
Published 2014-01-01

Meganuclease targeting HSV-1 protects against herpetic keratitis: Application to corneal transplants

by Benoit Chapellier, Damien Guindolet, Daniel Pereira, Roman Galetto, José-Alain Sahel, Marc Labetoulle, Eric E. Gabison
Published 2022-12-01

143 Mesothelin (MSLN) targeting allogeneic CAR T cells engineered to overcome tumor immunosuppressive microenvironment

by Agnes Gouble, Roman Galetto, Cécile Schiffer-Mannioui, Sophie Leduc, Isabelle Chion-Sotinel, Diane le Clerre, Valérie Guyot, Marco Rotondi
Published 2021-11-01

Molecular mechanisms of recombination restriction in the envelope gene of the human immunodeficiency virus.

by Etienne Simon-Loriere, Roman Galetto, Meriem Hamoudi, John Archer, Pierre Lefeuvre, Darren P Martin, David L Robertson, Matteo Negroni
Published 2009-05-01

Targeted gene therapy of xeroderma pigmentosum cells using meganuclease and TALEN™.

by Aurélie Dupuy, Julien Valton, Sophie Leduc, Jacques Armier, Roman Galetto, Agnès Gouble, Céline Lebuhotel, Anne Stary, Frédéric Pâques, Philippe Duchateau, Alain Sarasin, Fayza Daboussi
Published 2013-01-01

In vitro Inactivation of Latent HSV by Targeted Mutagenesis Using an HSV-specific Homing Endonuclease

by Martine Aubert, Nicole M Boyle, Daniel Stone, Laurence Stensland, Meei-Li Huang, Amalia S Magaret, Roman Galetto, David J Rawlings, Andrew M Scharenberg, Keith R Jerome
Published 2014-01-01

Allogeneic TCRαβ deficient CAR T-cells targeting CD123 in acute myeloid leukemia

by Mayumi Sugita, Roman Galetto, Hongliang Zong, Nathan Ewing-Crystal, Vicenta Trujillo-Alonso, Nuria Mencia-Trinchant, Winnie Yip, Stephanie Filipe, Celine Lebuhotel, Agnès Gouble, Duane C. Hassane, Julianne Smith, Gail J. Roboz, Monica L. Guzman
Published 2022-04-01

Gene editing and elimination of latent herpes simplex virus in vivo

by Martine Aubert, Daniel E. Strongin, Pavitra Roychoudhury, Michelle A. Loprieno, Anoria K. Haick, Lindsay M. Klouser, Laurence Stensland, Meei-Li Huang, Negar Makhsous, Alexander Tait, Harshana S. De Silva Feelixge, Roman Galetto, Philippe Duchateau, Alexander L. Greninger, Daniel Stone, Keith R. Jerome
Published 2020-08-01

Endowing universal CAR T-cell with immune-evasive properties using TALEN-gene editing

by Sumin Jo, Shipra Das, Alan Williams, Anne-Sophie Chretien, Thomas Pagliardini, Aude Le Roy, Jorge Postigo Fernandez, Diane Le Clerre, Billal Jahangiri, Isabelle Chion-Sotinel, Sandra Rozlan, Emilie Dessez, Agnes Gouble, Mathilde Dusséaux, Roman Galetto, Aymeric Duclert, Emanuela Marcenaro, Raynier Devillier, Daniel Olive, Philippe Duchateau, Laurent Poirot, Julien Valton
Published 2022-06-01

Non-viral DNA delivery and TALEN editing correct the sickle cell mutation in hematopoietic stem cells

by Arianna Moiani, Gil Letort, Sabrina Lizot, Anne Chalumeau, Chloe Foray, Tristan Felix, Diane Le Clerre, Sonal Temburni-Blake, Patrick Hong, Sophie Leduc, Noemie Pinard, Alan Marechal, Eduardo Seclen, Alex Boyne, Louisa Mayer, Robert Hong, Sylvain Pulicani, Roman Galetto, Agnès Gouble, Marina Cavazzana, Alexandre Juillerat, Annarita Miccio, Aymeric Duclert, Philippe Duchateau, Julien Valton
Published 2024-06-01

Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells

by Zita Garate, Oscar Quintana-Bustamante, Ana M. Crane, Emmanuel Olivier, Laurent Poirot, Roman Galetto, Penelope Kosinski, Collin Hill, Charles Kung, Xabi Agirre, Israel Orman, Laura Cerrato, Omaira Alberquilla, Fatima Rodriguez-Fornes, Noemi Fusaki, Felix Garcia-Sanchez, Tabita M. Maia, Maria L. Ribeiro, Julian Sevilla, Felipe Prosper, Shengfang Jin, Joanne Mountford, Guillermo Guenechea, Agnes Gouble, Juan A. Bueren, Brian R. Davis, Jose C. Segovia
Published 2015-12-01

Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells

by Tianyu Cai, Agnès Gouble, Kathryn L. Black, Anna Skwarska, Ammar S. Naqvi, Deanne Taylor, Ming Zhao, Qi Yuan, Mayumi Sugita, Qi Zhang, Roman Galetto, Stéphanie Filipe, Antonio Cavazos, Lina Han, Vinitha Kuruvilla, Helen Ma, Connie Weng, Chang-Gong Liu, Xiuping Liu, Sergej Konoplev, Jun Gu, Guilin Tang, Xiaoping Su, Gheath Al-Atrash, Stefan Ciurea, Sattva S. Neelapu, Andrew A. Lane, Hagop Kantarjian, Monica L. Guzman, Naveen Pemmaraju, Julianne Smith, Andrei Thomas-Tikhonenko, Marina Konopleva
Published 2022-04-01