IL-12 Expands and Differentiates Human Vγ2Vδ2 T Effector Cells Producing Antimicrobial Cytokines and Inhibiting Intracellular Mycobacterial Growth

by Rui Yang, Lan Yao, Ling Shen, Wei Sha, Robert L. Modlin, Robert L. Modlin, Hongbo Shen, Zheng W. Chen
Published 2019-04-01

Corrigendum: IL-12 Expands and Differentiates Human Vγ2Vδ2 T Effector Cells Producing Antimicrobial Cytokines and Inhibiting Intracellular Mycobacterial Growth

by Rui Yang, Lan Yao, Ling Shen, Wei Sha, Robert L. Modlin, Robert L. Modlin, Hongbo Shen, Zheng W. Chen
Published 2019-07-01

Impact of vitamin D on immune function: lessons learned from genome-wide analysis

by Rene F Chun, Philip T Liu, Robert L Modlin, John S Adams, Martin eHewison
Published 2014-04-01

Vitamin D status contributes to the antimicrobial activity of macrophages against Mycobacterium leprae.

by Elliot W Kim, Rosane M B Teles, Salem Haile, Philip T Liu, Robert L Modlin
Published 2018-07-01

SaVanT: a web-based tool for the sample-level visualization of molecular signatures in gene expression profiles

by David Lopez, Dennis Montoya, Michael Ambrose, Larry Lam, Leah Briscoe, Claire Adams, Robert L. Modlin, Matteo Pellegrini
Published 2017-10-01

Intrinsic activation of the vitamin D antimicrobial pathway by M. leprae infection is inhibited by type I IFN.

by Kathryn Zavala, Carter A Gottlieb, Rosane M Teles, John S Adams, Martin Hewison, Robert L Modlin, Philip T Liu
Published 2018-10-01

Identification of Genes Encoding Antimicrobial Proteins in Langerhans Cells

by Aislyn Oulee, Feiyang Ma, Feiyang Ma, Feiyang Ma, Rosane M. B. Teles, Bruno J. de Andrade Silva, Matteo Pellegrini, Eynav Klechevsky, Andrew N. Harman, Andrew N. Harman, Jake W. Rhodes, Jake W. Rhodes, Robert L. Modlin, Robert L. Modlin
Published 2021-08-01

IFN-γ-mediated control of SARS-CoV-2 infection through nitric oxide

by Bruno J. de Andrade Silva, Paul A. Krogstad, Paul A. Krogstad, Rosane M. B. Teles, Priscila R. Andrade, Jacob Rajfer, Monica G. Ferrini, Monica G. Ferrini, Otto O. Yang, Otto O. Yang, Barry R. Bloom, Robert L. Modlin, Robert L. Modlin
Published 2023-12-01

Jagged1 Instructs Macrophage Differentiation in Leprosy.

by Jon Kibbie, Rosane M B Teles, Zhiming Wang, Patrick Hong, Dennis Montoya, Stephan Krutzik, Seung Lee, Ohyun Kwon, Robert L Modlin, Daniel Cruz
Published 2016-08-01

ER Stress Regulates Immunosuppressive Function of Myeloid Derived Suppressor Cells in Leprosy that Can Be Overcome in the Presence of IFN-γ

by Kindra M. Kelly-Scumpia, Aaron Choi, Roksana Shirazi, Hannah Bersabe, Esther Park, Philip O. Scumpia, Maria T. Ochoa, Jing Yu, Feiyang Ma, Matteo Pellegrini, Robert L. Modlin
Published 2020-05-01

A CD4+CD161+ T-Cell Subset Present in Unexposed Humans, Not Tb Patients, Are Fast Acting Cells That Inhibit the Growth of Intracellular Mycobacteria Involving CD161 Pathway, Perfor...

by Rui Yang, Rui Yang, Ying Peng, Jiang Pi, Yidian Liu, Enzhuo Yang, Xiaona Shen, Lan Yao, Ling Shen, Robert L. Modlin, Hongbo Shen, Wei Sha, Zheng W. Chen
Published 2021-02-01

Opposing roles of Toll-like receptor and cytosolic DNA-STING signaling pathways for Staphylococcus aureus cutaneous host defense.

by Philip O Scumpia, Giovanni A Botten, Joshua S Norman, Kindra M Kelly-Scumpia, Roberto Spreafico, Amber R Ruccia, Prabhat K Purbey, Brandon J Thomas, Robert L Modlin, Stephen T Smale
Published 2017-07-01

The cell fate regulator NUPR1 is induced by Mycobacterium leprae via type I interferon in human leprosy.

by Priscila R Andrade, Manali Mehta, Jing Lu, Rosane M B Teles, Dennis Montoya, Phillip O Scumpia, Euzenir Nunes Sarno, Maria Teresa Ochoa, Feiyang Ma, Matteo Pellegrini, Robert L Modlin
Published 2019-07-01

Identification of a systemic interferon-γ inducible antimicrobial gene signature in leprosy patients undergoing reversal reaction.

by Rosane M B Teles, Jing Lu, Maria Tió-Coma, Isabela M B Goulart, Sayera Banu, Deanna Hagge, Kidist Bobosha, Tom H M Ottenhoff, Matteo Pellegrini, Annemieke Geluk, Robert L Modlin
Published 2019-10-01

Vitamin A Metabolism by Dendritic Cells Triggers an Antimicrobial Response against <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

by Elliot W. Kim, Avelino De Leon, Zhichun Jiang, Roxana A. Radu, Adrian R. Martineau, Edward D. Chan, Xiyuan Bai, Wen-Lin Su, Dennis J. Montoya, Robert L. Modlin, Philip T. Liu
Published 2019-06-01

Convergence of IL-1beta and VDR activation pathways in human TLR2/1-induced antimicrobial responses.

by Philip T Liu, Mirjam Schenk, Valencia P Walker, Paul W Dempsey, Melissa Kanchanapoomi, Matthew Wheelwright, Aria Vazirnia, Xiaoran Zhang, Andreas Steinmeyer, Ulrich Zügel, Bruce W Hollis, Genhong Cheng, Robert L Modlin
Published 2009-06-01

Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis

by Bryan D. Bryson, Tracy R. Rosebrock, Fikadu G. Tafesse, Christopher Y. Itoh, Armel Nibasumba, Gregory H. Babunovic, Bjorn Corleis, Constance Martin, Caroline Keegan, Priscila Andrade, Susan Realegeno, Douglas Kwon, Robert L. Modlin, Sarah M. Fortune
Published 2019-05-01

Human lung-resident mucosal-associated invariant T cells are abundant, express antimicrobial proteins, and are cytokine responsive

by Erin W. Meermeier, Christina L. Zheng, Jessica G. Tran, Shogo Soma, Aneta H. Worley, David I. Weiss, Robert L. Modlin, Gwendolyn Swarbrick, Elham Karamooz, Sharon Khuzwayo, Emily B. Wong, Marielle C. Gold, David M. Lewinsohn
Published 2022-09-01

<named-content content-type="genus-species">Propionibacterium acnes</named-content> Bacteriophages Display Limited Genetic Diversity and Broad Killing Activity against Bacterial Sk...

by Laura J. Marinelli, Sorel Fitz-Gibbon, Clarmyra Hayes, Charles Bowman, Megan Inkeles, Anya Loncaric, Daniel A. Russell, Deborah Jacobs-Sera, Shawn Cokus, Matteo Pellegrini, Jenny Kim, Jeff F. Miller, Graham F. Hatfull, Robert L. Modlin
Published 2012-11-01

IL-32γ potentiates tumor immunity in melanoma

by Thomas Gruber, Mirela Kremenovic, Hassan Sadozai, Nives Rombini, Lukas Baeriswyl, Fabienne Maibach, Robert L. Modlin, Michel Gilliet, Diego von Werdt, Robert E. Hunger, S. Morteza Seyed Jafari, Giulia Parisi, Gabriel Abril-Rodriguez, Antoni Ribas, Mirjam Schenk
Published 2020-09-01