Multiplexed capture of spatial configuration and temporal dynamics of locus-specific 3D chromatin by biotinylated dCas9

by Xin Liu, Yong Chen, Yuannyu Zhang, Yuxuan Liu, Nan Liu, Giovanni A. Botten, Hui Cao, Stuart H. Orkin, Michael Q. Zhang, Jian Xu
Published 2020-03-01

Inner nuclear protein Matrin-3 coordinates cell differentiation by stabilizing chromatin architecture

by Hye Ji Cha, Özgün Uyan, Yan Kai, Tianxin Liu, Qian Zhu, Zuzana Tothova, Giovanni A. Botten, Jian Xu, Guo-Cheng Yuan, Job Dekker, Stuart H. Orkin
Published 2021-10-01

Opposing roles of Toll-like receptor and cytosolic DNA-STING signaling pathways for Staphylococcus aureus cutaneous host defense.

by Philip O Scumpia, Giovanni A Botten, Joshua S Norman, Kindra M Kelly-Scumpia, Roberto Spreafico, Amber R Ruccia, Prabhat K Purbey, Brandon J Thomas, Robert L Modlin, Stephen T Smale
Published 2017-07-01

Cell Surface N-Glycans Influence Electrophysiological Properties and Fate Potential of Neural Stem Cells

by Andrew R. Yale, Jamison L. Nourse, Kayla R. Lee, Syed N. Ahmed, Janahan Arulmoli, Alan Y.L. Jiang, Lisa P. McDonnell, Giovanni A. Botten, Abraham P. Lee, Edwin S. Monuki, Michael Demetriou, Lisa A. Flanagan
Published 2018-10-01

Pathogenic human variant that dislocates GATA2 zinc fingers disrupts hematopoietic gene expression and signaling networks

by Mabel Minji Jung, Siqi Shen, Giovanni A. Botten, Thomas Olender, Koichi R. Katsumura, Kirby D. Johnson, Alexandra A. Soukup, Peng Liu, Qingzhou Zhang, Zena D. Jensvold, Peter W. Lewis, Robert A. Beagrie, Jason K.K. Low, Lihua Yang, Joel P. Mackay, Lucy A. Godley, Marjorie Brand, Jian Xu, Sunduz Keles, Emery H. Bresnick
Published 2023-04-01