Mendelian randomization and genetic colocalization infer the effects of the multi-tissue proteome on 211 complex disease-related phenotypes

by Chengran Yang, Anne M. Fagan, Richard J. Perrin, Herve Rhinn, Oscar Harari, Carlos Cruchaga
Published 2022-12-01

Neuroinflammation and Myelin Status in Alzheimer’s Disease, Parkinson’s Disease, and Normal Aging Brains: A Small Sample Study

by Fei Han, Richard J. Perrin, Qing Wang, Yong Wang, Joel S. Perlmutter, John C. Morris, Tammie L. S. Benzinger, Jinbin Xu
Published 2019-01-01

Regional correlation of biochemical measures of amyloid and tau phosphorylation in the brain

by Kanta Horie, Nicolas R. Barthélemy, Nipun Mallipeddi, Yan Li, Erin E. Franklin, Richard J. Perrin, Randall J. Bateman, Chihiro Sato
Published 2020-08-01

Flortaucipir (tau) PET in LGI1 antibody encephalitis

by Gregory S. Day, Brian A. Gordon, Austin McCullough, Robert C. Bucelli, Richard J. Perrin, Tammie L. S. Benzinger, Beau M. Ances
Published 2021-02-01

Translocator protein in late stage Alzheimer’s disease and Dementia with Lewy bodies brains

by Jinbin Xu, Jianjun Sun, Richard J. Perrin, Robert H. Mach, Kelly R. Bales, John C. Morris, Tammie L. S. Benzinger, David M. Holtzman
Published 2019-08-01

Calvarial Langerhans cell histiocytosis in an Adult: Typical imaging findings in an atypical age group

by Amjad Samara, MD, Jordan Nepute, MD, Hsiang-Chih Lu, MD, PhD, Richard J. Perrin, MD, PhD, Rami W. Eldaya, MD, MBA
Published 2019-12-01

Quantitative label-free proteomics for discovery of biomarkers in cerebrospinal fluid: assessment of technical and inter-individual variation.

by Richard J Perrin, Jacqueline E Payton, James P Malone, Petra Gilmore, Alan E Davis, Chengjie Xiong, Anne M Fagan, R Reid Townsend, David M Holtzman
Published 2013-01-01

Multiplexed immunoassay panel identifies novel CSF biomarkers for Alzheimer's disease diagnosis and prognosis.

by Rebecca Craig-Schapiro, Max Kuhn, Chengjie Xiong, Eve H Pickering, Jingxia Liu, Thomas P Misko, Richard J Perrin, Kelly R Bales, Holly Soares, Anne M Fagan, David M Holtzman
Published 2011-04-01

Non-beta-amyloid/tau cerebrospinal fluid markers inform staging and progression in Alzheimer’s disease

by Umesh Gangishetti, J. Christina Howell, Richard J. Perrin, Natalia Louneva, Kelly D. Watts, Alexander Kollhoff, Murray Grossman, David A. Wolk, Leslie M. Shaw, John C. Morris, John Q. Trojanowski, Anne M. Fagan, Steven E. Arnold, William T. Hu
Published 2018-09-01

Quantifying regional α ‐synuclein, amyloid β, and tau accumulation in lewy body dementia

by Rebecca L. Miller, Dhruva D. Dhavale, Jennifer Y. O’Shea, Kristin M. Andruska, Jialu Liu, Erin E. Franklin, Chandana Buddhala, Susan K. Loftin, John R. Cirrito, Richard J. Perrin, Nigel J. Cairns, Meghan C. Campbell, Joel S. Perlmutter, Paul T. Kotzbauer
Published 2022-02-01

TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers

by Jorge L. Del-Aguila, Bruno A. Benitez, Zeran Li, Umber Dube, Kathie A. Mihindukulasuriya, John P. Budde, Fabiana H. G. Farias, Maria Victoria Fernández, Laura Ibanez, Shan Jiang, Richard J. Perrin, Nigel J. Cairns, John C. Morris, Oscar Harari, Carlos Cruchaga
Published 2019-05-01

A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain

by Jorge L. Del-Aguila, Zeran Li, Umber Dube, Kathie A. Mihindukulasuriya, John P. Budde, Maria Victoria Fernandez, Laura Ibanez, Joseph Bradley, Fengxian Wang, Kristy Bergmann, Richard Davenport, John C. Morris, David M. Holtzman, Richard J. Perrin, Bruno A. Benitez, Joseph Dougherty, Carlos Cruchaga, Oscar Harari
Published 2019-08-01

Detection of emerging neurodegeneration using Bayesian linear mixed-effect modeling

by Yann Cobigo, Matthew S. Goh, Amy Wolf, Adam M. Staffaroni, John Kornak, Bruce L. Miller, Gil D. Rabinovici, William W. Seeley, Salvatore Spina, Adam L. Boxer, Bradley F. Boeve, Lei Wang, Ricardo Allegri, Marty Farlow, Hiroshi Mori, Richard J. Perrin, Joel Kramer, Howard J. Rosen
Published 2022-01-01

A peptide-centric quantitative proteomics dataset for the phenotypic assessment of Alzheimer’s disease

by Gennifer E. Merrihew, Jea Park, Deanna Plubell, Brian C. Searle, C. Dirk Keene, Eric B. Larson, Randall Bateman, Richard J. Perrin, Jasmeer P. Chhatwal, Martin R. Farlow, Catriona A. McLean, Bernardino Ghetti, Kathy L. Newell, Matthew P. Frosch, Thomas J. Montine, Michael J. MacCoss
Published 2023-04-01

Detection of neoantigen-specific T cells following a personalized vaccine in a patient with glioblastoma

by Tanner M. Johanns, Christopher A. Miller, Connor J. Liu, Richard J. Perrin, Diane Bender, Dale K. Kobayashi, Jian L. Campian, Michael R. Chicoine, Ralph G. Dacey, Jiayi Huang, Edward F. Fritsch, William E. Gillanders, Maxim N. Artyomov, Elaine R. Mardis, Robert D. Schreiber, Gavin P. Dunn
Published 2019-04-01

Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease.

by Richard J Perrin, Rebecca Craig-Schapiro, James P Malone, Aarti R Shah, Petra Gilmore, Alan E Davis, Catherine M Roe, Elaine R Peskind, Ge Li, Douglas R Galasko, Christopher M Clark, Joseph F Quinn, Jeffrey A Kaye, John C Morris, David M Holtzman, R Reid Townsend, Anne M Fagan
Published 2011-01-01

Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer's disease.

by Abdallah M Eteleeb, Brenna C Novotny, Carolina Soriano Tarraga, Christopher Sohn, Eliza Dhungel, Logan Brase, Aasritha Nallapu, Jared Buss, Fabiana Farias, Kristy Bergmann, Joseph Bradley, Joanne Norton, Jen Gentsch, Fengxian Wang, Albert A Davis, John C Morris, Celeste M Karch, Richard J Perrin, Bruno A Benitez, Oscar Harari
Published 2024-04-01

Multimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages: a cross-sectional observational study

by Peter R Millar, Brian A Gordon, Patrick H Luckett, Tammie LS Benzinger, Carlos Cruchaga, Anne M Fagan, Jason J Hassenstab, Richard J Perrin, Suzanne E Schindler, Ricardo F Allegri, Gregory S Day, Martin R Farlow, Hiroshi Mori, Georg Nübling, The Dominantly Inherited Alzheimer Network, Randall J Bateman, John C Morris, Beau M Ances
Published 2023-01-01

Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease

by Hsiang-Han Chen, Abdallah Eteleeb, Ciyang Wang, Maria Victoria Fernandez, John P. Budde, Kristy Bergmann, Joanne Norton, Fengxian Wang, Curtis Ebl, John C. Morris, Richard J. Perrin, Randall J. Bateman, Eric McDade, Chengjie Xiong, Alison Goate, Martin Farlow, Jasmeer Chhatwal, Peter R. Schofield, Helena Chui, Oscar Harari, Carlos Cruchaga, Laura Ibanez, Dominantly Inherited Alzheimer Network
Published 2022-03-01

Covariance-based vs. correlation-based functional connectivity dissociates healthy aging from Alzheimer disease

by Jeremy F. Strain, Matthew R. Brier, Aaron Tanenbaum, Brian A. Gordon, John E. McCarthy, Aylin Dincer, Daniel S. Marcus, Jasmeer P. Chhatwal, Neill R. Graff-Radford, Gregory S. Day, Christian la Fougère, Richard J. Perrin, Stephen Salloway, Peter R. Schofield, Igor Yakushev, Takeshi Ikeuchi, Jonathan Vöglein, John C. Morris, Tammie L.S. Benzinger, Randall J. Bateman, Beau M. Ances, Abraham Z. Snyder
Published 2022-11-01