Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain.

by Nina Geidenstam, Yu-Han H Hsu, Christina M Astley, Josep M Mercader, Martin Ridderstråle, Maria E Gonzalez, Clicerio Gonzalez, Joel N Hirschhorn, Rany M Salem
Published 2019-01-01

Causal association of cognitive reserve on Alzheimer's disease with putative sex difference

by Hao Wang, Brin Sara Rosenthal, Carolina Makowski, Min‐Tzu Lo, Ole A. Andreassen, Rany M. Salem, Linda K. McEvoy, Mark Fiecas, Chi‐Hua Chen
Published 2021-01-01

Similar Genetic Architecture of Alzheimer’s Disease and Differential APOE Effect Between Sexes

by Hao Wang, Min-Tzu Lo, Sara Brin Rosenthal, Carolina Makowski, Ole A. Andreassen, Rany M. Salem, Linda K. McEvoy, Linda K. McEvoy, Mark Fiecas, Chi-Hua Chen
Published 2021-05-01

Markers of kidney function, genetic variation related to cognitive function, and cognitive performance in the UK Biobank

by Erin L. Richard, Linda K. McEvoy, Ian J. Deary, Gail Davies, Steven Y. Cao, Eyal Oren, John E. Alcaraz, Andrea Z. LaCroix, Jan Bressler, Rany M. Salem
Published 2022-04-01

Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study.

by Erin N Smith, Wei Chen, Mika Kähönen, Johannes Kettunen, Terho Lehtimäki, Leena Peltonen, Olli T Raitakari, Rany M Salem, Nicholas J Schork, Marian Shaw, Sathanur R Srinivasan, Eric J Topol, Jorma S Viikari, Gerald S Berenson, Sarah S Murray
Published 2010-09-01

Differential Methylation of Telomere-Related Genes Is Associated with Kidney Disease in Individuals with Type 1 Diabetes

by Claire Hill, Seamus Duffy, Laura M. Kettyle, Liane McGlynn, Niina Sandholm, Rany M. Salem, Alex Thompson, Elizabeth J. Swan, Jill Kilner, Peter Rossing, Paul G. Shiels, Maria Lajer, Per-Henrik Groop, Alexander Peter Maxwell, Amy Jayne McKnight, on behalf of the GENIE Consortium
Published 2023-04-01

Effects of genetically predicted posttraumatic stress disorder on autoimmune phenotypes

by Adam X. Maihofer, Andrew Ratanatharathorn, Sian M. J. Hemmings, Karen H. Costenbader, Vasiliki Michopoulos, Renato Polimanti, Alex O. Rothbaum, Soraya Seedat, Elizabeth A. Mikita, CHARGE Inflammation Working Group, Psychiatric Genomics Consortium PTSD Working Group, Alicia K. Smith, Rany M. Salem, Richard A. Shaffer, Tianying Wu, Jonathan Sebat, Kerry J. Ressler, Murray B. Stein, Karestan C. Koenen, Erika J. Wolf, Jennifer A. Sumner, Caroline M. Nievergelt
Published 2024-04-01

Epigenome-wide meta-analysis identifies DNA methylation biomarkers associated with diabetic kidney disease

by Laura J. Smyth, Emma H. Dahlström, Anna Syreeni, Katie Kerr, Jill Kilner, Ross Doyle, Eoin Brennan, Viji Nair, Damian Fermin, Robert G. Nelson, Helen C. Looker, Christopher Wooster, Darrell Andrews, Kerry Anderson, Gareth J. McKay, Joanne B. Cole, Rany M. Salem, Peter J. Conlon, Matthias Kretzler, Joel N. Hirschhorn, Denise Sadlier, Catherine Godson, Jose C. Florez, GENIE consortium, Carol Forsblom, Alexander P. Maxwell, Per-Henrik Groop, Niina Sandholm, Amy Jayne McKnight
Published 2022-12-01

Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response

by Meghana Pagadala, Timothy J. Sears, Victoria H. Wu, Eva Pérez-Guijarro, Hyo Kim, Andrea Castro, James V. Talwar, Cristian Gonzalez-Colin, Steven Cao, Benjamin J. Schmiedel, Shervin Goudarzi, Divya Kirani, Jessica Au, Tongwu Zhang, Teresa Landi, Rany M. Salem, Gerald P. Morris, Olivier Harismendy, Sandip Pravin Patel, Ludmil B. Alexandrov, Jill P. Mesirov, Maurizio Zanetti, Chi-Ping Day, Chun Chieh Fan, Wesley K. Thompson, Glenn Merlino, J. Silvio Gutkind, Pandurangan Vijayanand, Hannah Carter
Published 2023-05-01

Distribution and medical impact of loss-of-function variants in the Finnish founder population.

by Elaine T Lim, Peter Würtz, Aki S Havulinna, Priit Palta, Taru Tukiainen, Karola Rehnström, Tõnu Esko, Reedik Mägi, Michael Inouye, Tuuli Lappalainen, Yingleong Chan, Rany M Salem, Monkol Lek, Jason Flannick, Xueling Sim, Alisa Manning, Claes Ladenvall, Suzannah Bumpstead, Eija Hämäläinen, Kristiina Aalto, Mikael Maksimow, Marko Salmi, Stefan Blankenberg, Diego Ardissino, Svati Shah, Benjamin Horne, Ruth McPherson, Gerald K Hovingh, Muredach P Reilly, Hugh Watkins, Anuj Goel, Martin Farrall, Domenico Girelli, Alex P Reiner, Nathan O Stitziel, Sekar Kathiresan, Stacey Gabriel, Jeffrey C Barrett, Terho Lehtimäki, Markku Laakso, Leif Groop, Jaakko Kaprio, Markus Perola, Mark I McCarthy, Michael Boehnke, David M Altshuler, Cecilia M Lindgren, Joel N Hirschhorn, Andres Metspalu, Nelson B Freimer, Tanja Zeller, Sirpa Jalkanen, Seppo Koskinen, Olli Raitakari, Richard Durbin, Daniel G MacArthur, Veikko Salomaa, Samuli Ripatti, Mark J Daly, Aarno Palotie, Sequencing Initiative Suomi (SISu) Project
Published 2014-07-01

New susceptibility loci associated with kidney disease in type 1 diabetes.

by Niina Sandholm, Rany M Salem, Amy Jayne McKnight, Eoin P Brennan, Carol Forsblom, Tamara Isakova, Gareth J McKay, Winfred W Williams, Denise M Sadlier, Ville-Petteri Mäkinen, Elizabeth J Swan, Cameron Palmer, Andrew P Boright, Emma Ahlqvist, Harshal A Deshmukh, Benjamin J Keller, Huateng Huang, Aila J Ahola, Emma Fagerholm, Daniel Gordin, Valma Harjutsalo, Bing He, Outi Heikkilä, Kustaa Hietala, Janne Kytö, Päivi Lahermo, Markku Lehto, Raija Lithovius, Anne-May Osterholm, Maija Parkkonen, Janne Pitkäniemi, Milla Rosengård-Bärlund, Markku Saraheimo, Cinzia Sarti, Jenny Söderlund, Aino Soro-Paavonen, Anna Syreeni, Lena M Thorn, Heikki Tikkanen, Nina Tolonen, Karl Tryggvason, Jaakko Tuomilehto, Johan Wadén, Geoffrey V Gill, Sarah Prior, Candace Guiducci, Daniel B Mirel, Andrew Taylor, S Mohsen Hosseini, DCCT/EDIC Research Group, Hans-Henrik Parving, Peter Rossing, Lise Tarnow, Claes Ladenvall, François Alhenc-Gelas, Pierre Lefebvre, Vincent Rigalleau, Ronan Roussel, David-Alexandre Tregouet, Anna Maestroni, Silvia Maestroni, Henrik Falhammar, Tianwei Gu, Anna Möllsten, Danut Cimponeriu, Mihai Ioana, Maria Mota, Eugen Mota, Cristian Serafinceanu, Monica Stavarachi, Robert L Hanson, Robert G Nelson, Matthias Kretzler, Helen M Colhoun, Nicolae Mircea Panduru, Harvest F Gu, Kerstin Brismar, Gianpaolo Zerbini, Samy Hadjadj, Michel Marre, Leif Groop, Maria Lajer, Shelley B Bull, Daryl Waggott, Andrew D Paterson, David A Savage, Stephen C Bain, Finian Martin, Joel N Hirschhorn, Catherine Godson, Jose C Florez, Per-Henrik Groop, Alexander P Maxwell
Published 2012-09-01

Recurring exon deletions in the haptoglobin (HP) gene associate with lower blood cholesterol levels

by Boettger, Linda M., Salem, Rany M., Handsaker, Robert E., Peloso, Gina, Kathiresan, Sekar, Hirschhorn, Joel, McCarroll, Steven A.
Published 2016

Efficient Bayesian mixed-model analysis increases association power in large cohorts

by Loh, Po-Ru, Bulik-Sullivan, Brendan K, Vilhjálmsson, Bjarni J, Salem, Rany M, Chasman, Daniel I, Ridker, Paul M, Neale, Benjamin M, Patterson, Nick, Price, Alkes L, Tucker, George Jay, Finucane, Hilary Kiyo, Berger Leighton, Bonnie
Published 2017

New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes

by Sandholm, Niina, Salem, Rany M., McKnight, Amy Jayne, Brennan, Eoin P., Forsblom, Carol, Isakova, Tamara, McKay, Gareth J., Williams, Winfred Woodrow, Sadlier, Denise M., Mäkinen, Ville-Petteri, Swan, Elizabeth J., Palmer, Cameron Douglas, Boright, Andrew P., Ahlqvist, Emma, Deshmukh, Harshal A., Keller, Benjamin J., Huang, Huateng, Ahola, Aila J., Fagerholm, Emma, Gordin, Daniel, Harjutsalo, Valma, He, Bing, Heikkilä, Outi, Hietala, Kustaa, Kytö, Janne, Lahermo, Päivi, Lehto, Markku, Lithovius, Raija, Österholm, Anne-May, Parkkonen, Maija, Pitkäniemi, Janne, Rosengård-Bärlund, Milla, Saraheimo, Markku, Sarti, Cinzia, Söderlund, Jenny, Soro-Paavonen, Aino, Syreeni, Anna, Thorn, Lena M., Tikkanen, Heikki, Tolonen, Nina, Tryggvason, Karl, Tuomilehto, Jaakko, Wadén, Johan, Gill, Geoffrey V., Prior, Sarah Virginie, Guiducci, Candace, Mirel, Daniel B., Taylor, Andrew, Hosseini, S. Mohsen, Parving, Hans-Henrik, Rossing, Peter, Tarnow, Lise, Ladenvall, Claes, Alhenc-Gelas, François, Lefebvre, Pierre, Rigalleau, Vincent, Roussel, Ronan, Tregouet, David-Alexandre, Maestroni, Anna, Maestroni, Silvia, Falhammar, Henrik, Gu, Tianwei, Möllsten, Anna, Cimponeriu, Danut, Ioana, Mihai, Mota, Maria, Mota, Eugen, Serafinceanu, Cristian, Stavarachi, Monica, Hanson, Robert L., Nelson, Robert G., Kretzler, Matthias, Colhoun, Helen M., Panduru, Nicolae Mircea, Gu, Harvest F., Brismar, Kerstin, Zerbini, Gianpaolo, Hadjadj, Samy, Marre, Michel, Groop, Leif, Lajer, Maria, Bull, Shelley B., Waggott, Daryl, Paterson, Andrew D., Savage, David A., Bain, Stephen C., Martin, Finian, Hirschhorn, Joel Naom, Godson, Catherine, Florez, Jose Carlos, Groop, Per-Henrik, Maxwell, Alexander P.
Published 2013