Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis

by Debra Van Egeren, Khushi Kohli, Jeremy L. Warner, Philippe L. Bedard, Gregory Riely, Eva Lepisto, Deborah Schrag, Michele LeNoue-Newton, Paul Catalano, Kenneth L. Kehl, Franziska Michor, for the AACR Project GENIE Consortium represented by Shawn Sweeney
Published 2022-11-01

Differential Methylation of Telomere-Related Genes Is Associated with Kidney Disease in Individuals with Type 1 Diabetes

by Claire Hill, Seamus Duffy, Laura M. Kettyle, Liane McGlynn, Niina Sandholm, Rany M. Salem, Alex Thompson, Elizabeth J. Swan, Jill Kilner, Peter Rossing, Paul G. Shiels, Maria Lajer, Per-Henrik Groop, Alexander Peter Maxwell, Amy Jayne McKnight, on behalf of the GENIE Consortium
Published 2023-04-01

Epigenome-wide meta-analysis identifies DNA methylation biomarkers associated with diabetic kidney disease

by Laura J. Smyth, Emma H. Dahlström, Anna Syreeni, Katie Kerr, Jill Kilner, Ross Doyle, Eoin Brennan, Viji Nair, Damian Fermin, Robert G. Nelson, Helen C. Looker, Christopher Wooster, Darrell Andrews, Kerry Anderson, Gareth J. McKay, Joanne B. Cole, Rany M. Salem, Peter J. Conlon, Matthias Kretzler, Joel N. Hirschhorn, Denise Sadlier, Catherine Godson, Jose C. Florez, GENIE consortium, Carol Forsblom, Alexander P. Maxwell, Per-Henrik Groop, Niina Sandholm, Amy Jayne McKnight
Published 2022-12-01

Genome-wide meta-analysis and omics integration identifies novel genes associated with diabetic kidney disease.

by Sandholm, Niina, Cole, Joanne B, Nair, Viji, Sheng, Xin, Liu, Hongbo, Ahlqvist, Emma, van Zuydam, Natalie, Dahlström, Emma H, Fermin, Damian, Smyth, Laura J, Salem, Rany M, Forsblom, Carol, Valo, Erkka, Harjutsalo, Valma, Brennan, Eoin P, McKay, Gareth J, Andrews, Darrell, Doyle, Ross, Looker, Helen C, Nelson, Robert G, Palmer, Colin, McKnight, Amy Jayne, Godson, Catherine, Maxwell, Alexander P, Groop, Leif, McCarthy, Mark I, Kretzler, Matthias, Susztak, Katalin, Hirschhorn, Joel N, Florez, Jose C, Groop, Per-Henrik, GENIE Consortium
Published 2022

Genetic risk factors affecting mitochondrial function are associated with kidney disease in people with Type 1 diabetes.

by Swan, EJ, Salem, RM, Sandholm, N, Tarnow, L, Rossing, P, Lajer, M, Groop, PH, Maxwell, AP, McKnight, AJ, GENIE Consortium
Published 2015

Association Testing of Previously Reported Variants in a Large Case-Control Meta-analysis of Diabetic Nephropathy

by Williams, Winfred W., Salem, Rany M., McKnight, Amy Jayne, Sandholm, Niina, Forsblom, Carol, Taylor, Andrew, Guiducci, Candace, McAteer, Jarred B., McKay, Gareth J., Isakova, Tamara, Brennan, Eoin P., Sadlier, Denise M., Palmer, Cameron, Söderlund, Jenny, Fagerholm, Emma, Harjutsalo, Valma, Lithovius, Raija, Gordin, Daniel, Hietala, Kustaa, Kytö, Janne, Parkkonen, Maija, Rosengård-Bärlund, Milla, Thorn, Lena, Syreeni, Anna, Tolonen, Nina, Saraheimo, Markku, Wadén, Johan, Pitkäniemi, Janne, Sarti, Cinzia, Tuomilehto, Jaakko, Tryggvason, Karl, Österholm, Anne-May, He, Bing, Bain, Steve, Martin, Finian, Godson, Catherine, Hirschhorn, Joel N., Maxwell, Alexander P., Groop, Per-Henrik, Florez, Jose C.
Published 2014

New genetic loci link adipose and insulin biology to body fat distribution.

by Shungin, Dmitry, Winkler, Thomas W, Croteau-Chonka, Damien C, Ferreira, Teresa, Locke, Adam E, Mägi, Reedik, Strawbridge, Rona J, Pers, Tune H, Fischer, Krista, Justice, Anne E, Workalemahu, Tsegaselassie, Wu, Joseph MW, Buchkovich, Martin L, Heard-Costa, Nancy L, Roman, Tamara S, Drong, Alexander W, Song, Ci, Gustafsson, Stefan, Day, Felix R, Esko, Tonu, Fall, Tove, Kutalik, Zoltán, Luan, Jian'an, Randall, Joshua C, Scherag, André, Vedantam, Sailaja, Wood, Andrew R, Chen, Jin, Fehrmann, Rudolf, Karjalainen, Juha, Kahali, Bratati, Liu, Ching-Ti, Schmidt, Ellen M, Absher, Devin, Amin, Najaf, Anderson, Denise, Beekman, Marian, Bragg-Gresham, Jennifer L, Buyske, Steven, Demirkan, Ayse, Ehret, Georg B, Feitosa, Mary F, Goel, Anuj, Jackson, Anne U, Johnson, Toby, Kleber, Marcus E, Kristiansson, Kati, Mangino, Massimo, Leach, Irene Mateo, Medina-Gomez, Carolina, Palmer, Cameron D, Pasko, Dorota, Pechlivanis, Sonali, Peters, Marjolein J, Prokopenko, Inga, Stančáková, Alena, Sung, Yun Ju, Tanaka, Toshiko, Teumer, Alexander, Van Vliet-Ostaptchouk, Jana V, Yengo, Loïc, Zhang, Weihua, Albrecht, Eva, Ärnlöv, Johan, Arscott, Gillian M, Bandinelli, Stefania, Barrett, Amy, Bellis, Claire, Bennett, Amanda J, Berne, Christian, Blüher, Matthias, Böhringer, Stefan, Bonnet, Fabrice, Böttcher, Yvonne, Bruinenberg, Marcel, Carba, Delia B, Caspersen, Ida H, Clarke, Robert, Daw, E Warwick, Deelen, Joris, Deelman, Ewa, Delgado, Graciela, Doney, Alex Sf, Eklund, Niina, Erdos, Michael R, Estrada, Karol, Eury, Elodie, Friedrich, Nele, Garcia, Melissa E, Giedraitis, Vilmantas, Gigante, Bruna, Go, Alan S, Golay, Alain, Grallert, Harald, Grammer, Tanja B, Gräßler, Jürgen, Grewal, Jagvir, Groves, Christopher J, Haller, Toomas, Hallmans, Goran
Published 2015

New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes

by Sandholm, Niina, Salem, Rany M., McKnight, Amy Jayne, Brennan, Eoin P., Forsblom, Carol, Isakova, Tamara, McKay, Gareth J., Williams, Winfred Woodrow, Sadlier, Denise M., Mäkinen, Ville-Petteri, Swan, Elizabeth J., Palmer, Cameron Douglas, Boright, Andrew P., Ahlqvist, Emma, Deshmukh, Harshal A., Keller, Benjamin J., Huang, Huateng, Ahola, Aila J., Fagerholm, Emma, Gordin, Daniel, Harjutsalo, Valma, He, Bing, Heikkilä, Outi, Hietala, Kustaa, Kytö, Janne, Lahermo, Päivi, Lehto, Markku, Lithovius, Raija, Österholm, Anne-May, Parkkonen, Maija, Pitkäniemi, Janne, Rosengård-Bärlund, Milla, Saraheimo, Markku, Sarti, Cinzia, Söderlund, Jenny, Soro-Paavonen, Aino, Syreeni, Anna, Thorn, Lena M., Tikkanen, Heikki, Tolonen, Nina, Tryggvason, Karl, Tuomilehto, Jaakko, Wadén, Johan, Gill, Geoffrey V., Prior, Sarah Virginie, Guiducci, Candace, Mirel, Daniel B., Taylor, Andrew, Hosseini, S. Mohsen, Parving, Hans-Henrik, Rossing, Peter, Tarnow, Lise, Ladenvall, Claes, Alhenc-Gelas, François, Lefebvre, Pierre, Rigalleau, Vincent, Roussel, Ronan, Tregouet, David-Alexandre, Maestroni, Anna, Maestroni, Silvia, Falhammar, Henrik, Gu, Tianwei, Möllsten, Anna, Cimponeriu, Danut, Ioana, Mihai, Mota, Maria, Mota, Eugen, Serafinceanu, Cristian, Stavarachi, Monica, Hanson, Robert L., Nelson, Robert G., Kretzler, Matthias, Colhoun, Helen M., Panduru, Nicolae Mircea, Gu, Harvest F., Brismar, Kerstin, Zerbini, Gianpaolo, Hadjadj, Samy, Marre, Michel, Groop, Leif, Lajer, Maria, Bull, Shelley B., Waggott, Daryl, Paterson, Andrew D., Savage, David A., Bain, Stephen C., Martin, Finian, Hirschhorn, Joel Naom, Godson, Catherine, Florez, Jose Carlos, Groop, Per-Henrik, Maxwell, Alexander P.
Published 2013