Canagliflozin Ameliorates Oxidative Stress and Autistic-like Features in Valproic-Acid-Induced Autism in Rats: Comparison with Aripiprazole Action

by Mohammed Moutaz Nakhal, Petrilla Jayaprakash, Salahdein Aburuz, Bassem Sadek, Amal Akour
Published 2023-05-01

Curcumin Potentiates α7 Nicotinic Acetylcholine Receptors and Alleviates Autistic-Like Social Deficits and Brain Oxidative Stress Status in Mice

by Petrilla Jayaprakash, Dmytro Isaev, Waheed Shabbir, Dietrich E. Lorke, Bassem Sadek, Murat Oz
Published 2021-07-01

Simultaneous Blockade of Histamine H₃ Receptors and Inhibition of Acetylcholine Esterase Alleviate Autistic-Like Behaviors in BTBR T+ tf/J Mouse Model of Autism

by Nermin Eissa, Petrilla Jayaprakash, Holger Stark, Dorota Łażewska, Katarzyna Kieć-Kononowicz, Bassem Sadek
Published 2020-08-01

Experimental Studies Indicate That ST-2223, the Antagonist of Histamine H3 and Dopamine D2/D3 Receptors, Restores Social Deficits and Neurotransmission Dysregulation in Mouse Model...

by Nermin Eissa, Karthikkumar Venkatachalam, Petrilla Jayaprakash, Priya Yuvaraju, Markus Falkenstein, Holger Stark, Bassem Sadek
Published 2022-07-01

Apigenin Alleviates Autistic-like Stereotyped Repetitive Behaviors and Mitigates Brain Oxidative Stress in Mice

by Petrilla Jayaprakash, Dmytro Isaev, Keun-Hang Susan Yang, Rami Beiram, Murat Oz, Bassem Sadek
Published 2024-04-01

The histamine H3R and dopamine D2R/D3R antagonist ST-713 ameliorates autism-like behavioral features in BTBR T+tf/J mice by multiple actions

by Karthikkumar Venkatachalam, Nermin Eissa, Mohamed Al Awad, Petrilla Jayaprakash, Sicheng Zhong, Frauke Stölting, Holger Stark, Bassem Sadek
Published 2021-06-01

Enhanced Glucose Tolerance and Pancreatic Beta Cell Function by Low Dose Aspirin in Hyperglycemic Insulin-Resistant Type 2 Diabetic Goto-Kakizaki (GK) Rats

by Layla Amiri, Annie John, Jasmin Shafarin, Ernest Adeghate, Petrilla Jayaprakash, Javed Yasin, Frank Christopher Howarth, Haider Raza
Published 2015-07-01

The Potent and Selective Histamine H3 Receptor Antagonist E169 Counteracts Cognitive Deficits and Mitigates Disturbances in the PI3K/AKT/GSK-3β Signaling Pathway in MK801-Induced A...

by Sabna Abdalla, Nermin Eissa, Petrilla Jayaprakash, Rami Beiram, Kamil J. Kuder, Dorota Łażewska, Katarzyna Kieć-Kononowicz, Bassem Sadek
Published 2023-08-01

Simultaneous Antagonism at H3R/D2R/D3R Reduces Autism-like Self-Grooming and Aggressive Behaviors by Mitigating MAPK Activation in Mice

by Nermin Eissa, Mohamed Al Awad, Shilu Deepa Thomas, Karthikkumar Venkatachalam, Petrilla Jayaprakash, Sicheng Zhong, Holger Stark, Bassem Sadek
Published 2022-12-01

Vitamin E ameliorates the decremental effect of paraquat on cardiomyocyte contractility in rats.

by Mohamed Abdelmonem Fahim, Frank Christopher Howarth, Abderrahim Nemmar, Mohamed Anwar Qureshi, Mohamed Shafiullah, Petrilla Jayaprakash, Mohamed Yousif Hasan
Published 2013-01-01

The Multi-Targeting Ligand ST-2223 with Histamine H₃ Receptor and Dopamine D₂/D₃ Receptor Antagonist Properties Mitigates Autism-Like Repetitive Be...

by Nermin Eissa, Karthikkumar Venkatachalam, Petrilla Jayaprakash, Markus Falkenstein, Mariam Dubiel, Annika Frank, David Reiner-Link, Holger Stark, Bassem Sadek
Published 2021-02-01

Different Profile of mRNA Expression in Sinoatrial Node from Streptozotocin-Induced Diabetic Rat.

by Zannatul Ferdous, Muhammad Anwar Qureshi, Petrilla Jayaprakash, Khatija Parekh, Annie John, Murat Oz, Haider Raza, Halina Dobrzynski, Thomas Edward Adrian, Frank Christopher Howarth
Published 2016-01-01

The Dual-Active Histamine H₃ Receptor Antagonist and Acetylcholine Esterase Inhibitor E100 Alleviates Autistic-Like Behaviors and Oxidative Stress in Valproic Acid Induc...

by Nermin Eissa, Sheikh Azimullah, Petrilla Jayaprakash, Richard L. Jayaraj, David Reiner, Shreesh K. Ojha, Rami Beiram, Holger Stark, Dorota Łażewska, Katarzyna Kieć-Kononowicz, Bassem Sadek
Published 2020-06-01