Local tissue development of type 1 innate lymphoid cells: guided by interferon-gamma

by Thomas M. Conlon, Percy A. Knolle, Ali Önder Yildirim
Published 2021-07-01

Improving Therapeutic Vaccination against Hepatitis B—Insights from Preclinical Models of Immune Therapy against Persistent Hepatitis B Virus Infection

by Percy A. Knolle, Li-Rung Huang, Anna Kosinska, Dirk Wohlleber, Ulrike Protzer
Published 2021-11-01

TIMP-1 signaling via CD63 triggers granulopoiesis and neutrophilia in mice

by Julia Kobuch, Haissi Cui, Barbara Grünwald, Paul Saftig, Percy A. Knolle, Achim Krüger
Published 2015-08-01

Linear B-Cell Epitopes in Human Norovirus GII.4 Capsid Protein Elicit Blockade Antibodies

by Hassan Moeini, Suliman Qadir Afridi, Sainitin Donakonda, Percy A. Knolle, Ulrike Protzer, Dieter Hoffmann
Published 2021-01-01

Montelukast is a dual-purpose inhibitor of SARS-CoV-2 infection and virus-induced IL-6 expression identified by structure-based drug repurposing

by Max Luedemann, Daniela Stadler, Cho-Chin Cheng, Ulrike Protzer, Percy A. Knolle, Sainitin Donakonda
Published 2022-01-01

Hepatitis B Vaccine Non-Responders Show Higher Frequencies of CD24highCD38high Regulatory B Cells and Lower Levels of IL-10 Expression Compared to Responders

by Nina Körber, Nina Körber, Laureen Pohl, Birgit Weinberger, Beatrix Grubeck-Loebenstein, Andrea Wawer, Percy A. Knolle, Percy A. Knolle, Hedwig Roggendorf, Hedwig Roggendorf, Ulrike Protzer, Ulrike Protzer, Ulrike Protzer, Tanja Bauer, Tanja Bauer
Published 2021-09-01

In Vivo Bioluminescence Imaging of HBV Replicating Hepatocytes Allows for the Monitoring of Anti-Viral Immunity

by Katrin Manske, Annika Schneider, Chunkyu Ko, Percy A. Knolle, Katja Steiger, Ulrike Protzer, Dirk Wohlleber
Published 2021-11-01

Liver sinusoidal endothelial cell-mediated CD8 T cell priming depends on co-inhibitory signal integration over time.

by Julita Kaczmarek, Yahya Homsi, Jan van Üüm, Christina Metzger, Percy A Knolle, Waldemar Kolanus, Thorsten Lang, Linda Diehl
Published 2014-01-01

Comparative Approach to Define Increased Regulatory T Cells in Different Cancer Subtypes by Combined Assessment of CD127 and FOXP3

by Marc Beyer, Sabine Classen, Elmar Endl, Matthias Kochanek, Martin R. Weihrauch, Svenja Debey-Pascher, Percy A. Knolle, Joachim L. Schultze
Published 2011-01-01

In vivo expansion of naïve CD4+ CD25(high) FOXP3+ regulatory T cells in patients with colorectal carcinoma after IL-2 administration.

by Marc Beyer, Beatrix Schumak, Martin R Weihrauch, Bettina Andres, Thomas Giese, Elmar Endl, Percy A Knolle, Sabine Classen, Andreas Limmer, Joachim L Schultze
Published 2012-01-01

Inflammatory Cues Direct Skin-Resident Type 1 Innate Lymphoid Cells to Adopt a Psoriasis-Promoting Identity

by Beatrix D.G. Evers, Miriam Hils, Christoph Heuser, Inga M. Hölge, Désirée Argiriu, Yuliya Skabytska, Susanne Kaesler, Christian Posch, Percy A. Knolle, Tilo Biedermann
Published 2023-07-01

Improved detection of infection with SARS-CoV-2 Omicron variants of concern in healthcare workers by a second-generation rapid antigen test

by Jochen M. Wettengel, Katharina Strehle, Catharina von Lucke, Hedwig Roggendorf, Samuel D. Jeske, Catharina Christa, Otto Zelger, Bernhard Haller, Ulrike Protzer, Percy A. Knolle
Published 2023-12-01

High precision-cut liver slice model to study cell-autonomous antiviral defense of hepatocytes within their microenvironment

by Marcus Brugger, Melanie Laschinger, Sandra Lampl, Annika Schneider, Katrin Manske, Dena Esfandyari, Norbert Hüser, Daniel Hartmann, Katja Steiger, Stefan Engelhardt, Dirk Wohlleber, Percy A. Knolle
Published 2022-05-01

IL-6 trans-Signaling-Dependent Rapid Development of Cytotoxic CD8+ T Cell Function

by Jan P. Böttcher, Oliver Schanz, Christoph Garbers, Anne Zaremba, Silke Hegenbarth, Christian Kurts, Marc Beyer, Joachim L. Schultze, Wolfgang Kastenmüller, Stefan Rose-John, Percy A. Knolle
Published 2014-09-01

Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells.

by Sören V Siegmund, Monika Schlosser, Frank A Schildberg, Ekihiro Seki, Samuele De Minicis, Hiroshi Uchinami, Christian Kuntzen, Percy A Knolle, Christian P Strassburg, Robert F Schwabe
Published 2016-01-01

Pioglitazone-Mediated Peroxisome Proliferator-Activated Receptor γ Activation Aggravates Murine Immune-Mediated Hepatitis

by Rike Schulte, Dirk Wohlleber, Ludmilla Unrau, Bernd Geers, Christina Metzger, Annette Erhardt, Gisa Tiegs, Nico van Rooijen, Lukas C. Heukamp, Luisa Klotz, Percy A. Knolle, Linda Diehl
Published 2020-04-01

Targeting myeloid derived suppressor cells with all-trans retinoic acid is highly time-dependent in therapeutic tumor vaccination

by Annkristin Heine, Chrystel Flores, Heidrun Gevensleben, Linda Diehl, Mathias Heikenwalder, Marc Ringelhan, Klaus-Peter Janssen, Ulrich Nitsche, Natalio Garbi, Peter Brossart, Percy A. Knolle, Christian Kurts, Bastian Höchst
Published 2017-08-01

mRNA 3’UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus

by Valter Bergant, Daniel Schnepf, Niklas de Andrade Krätzig, Philipp Hubel, Christian Urban, Thomas Engleitner, Ronald Dijkman, Bernhard Ryffel, Katja Steiger, Percy A. Knolle, Georg Kochs, Roland Rad, Peter Staeheli, Andreas Pichlmair
Published 2023-08-01

T-Cell-Dominated Immune Response Resolves Protracted SARS-CoV-2 Infection in the Absence of Neutralizing Antibodies in an Immunocompromised Individual

by Till Bunse, Nina Koerber, Hannah Wintersteller, Jochen Schneider, Alexander Graf, Aleksandar Radonic, Andrea Thuermer, Max von Kleist, Helmut Blum, Christoph D. Spinner, Tanja Bauer, Percy A. Knolle, Ulrike Protzer, Eva C. Schulte
Published 2023-06-01

STAT5 is an ambivalent regulator of neutrophil homeostasis.

by Laurence Fiévez, Christophe Desmet, Emmanuelle Henry, Bernard Pajak, Silke Hegenbarth, Virginie Garzé, Françoise Bex, Fabrice Jaspar, Philippe Boutet, Laurent Gillet, Alain Vanderplasschen, Percy A Knolle, Oberdan Leo, Muriel Moser, Pierre Lekeux, Fabrice Bureau
Published 2007-01-01